公开(公告)号：US20240141049A1

公开(公告)日：2024-05-02

申请号：US18361782

申请日：2023-07-28

Applicant: Surrozen Operating, Inc.

Inventor： Yang LI ,  Tom Zhiye YUAN ,  Aaron Ken SATO ,  Wen-Chen YEH ,  Claudia Yvonne JANDA ,  Tristan William FOWLER ,  Helene BARIBAULT ,  Kuo-Pao LAI ,  Liqin XIE ,  Randall J. BREZSKI ,  Chenggang LU

IPC: C07K16/28 ,  C07K16/46

CPC classification number: C07K16/2863 ,  C07K16/468 ,  A61K2039/505

Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

公开(公告)号：US20220195053A1

公开(公告)日：2022-06-23

申请号：US17438303

申请日：2020-03-11

Applicant: Surrozen Operating Inc.

Inventor： Yang LI ,  Chenggang LU ,  Hélène BARIBAULT ,  Wen-Chen YEH ,  Liqin XIE ,  I-Chieh WANG ,  Weixu MENG

IPC: C07K16/28 ,  A61P1/00

Abstract: The present invention provides methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway. Also provided are methods of dosing and pharmaceutical compositions.

公开(公告)号：US20240150473A1

公开(公告)日：2024-05-09

申请号：US18281253

申请日：2022-03-09

Applicant: Surrozen Operating, Inc.

Inventor： Russell FLETCHER ,  Sungjin LEE ,  Yang LI ,  Chenggang LU ,  Parthasarathy SAMPATHKUMAR ,  Geertrui VANHOVE ,  Wen-Chen YEH ,  Liqin XIE ,  Leonard PRESTA

IPC: C07K16/28 ,  A01N1/02 ,  A61P1/00 ,  A61P29/00 ,  C12N5/071

CPC classification number: C07K16/2863 ,  A01N1/0226 ,  A61P1/00 ,  A61P29/00 ,  C07K16/28 ,  C12N5/0679 ,  A61K2039/505 ,  C07K2317/22 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/569 ,  C07K2317/75

Abstract: The present disclosure provides engineered WNT agonists and methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway.