公开(公告)号：US11746150B2

公开(公告)日：2023-09-05

申请号：US16954483

申请日：2018-12-19

Applicant: Surrozen Operating, Inc.

Inventor： Yang Li ,  Tom Zhiye Yuan ,  Aaron Ken Sato ,  Wen-Chen Yeh ,  Parthasarathy Sampathkumar

IPC: C07K16/28

CPC classification number: C07K16/28 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/569 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2319/30

Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.

公开(公告)号：US12006368B2

公开(公告)日：2024-06-11

申请号：US16954482

申请日：2018-12-19

Applicant: Surrozen Operating, Inc.

Inventor： Yang Li ,  Tom Zhiye Yuan ,  Aaron Ken Sato ,  Wen-Chen Yeh ,  Chenggang Lu ,  Parthasarathy Sampathkumar ,  Claudia Yvonne Janda

IPC: C07K16/28

CPC classification number: C07K16/2863 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/569 ,  C07K2317/92 ,  C07K2319/00

Abstract: The present invention provides anti-Fzd monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

公开(公告)号：US11958891B2

公开(公告)日：2024-04-16

申请号：US16481001

申请日：2018-01-26

Applicant: Surrozen Operating, Inc.

Inventor： Zhengjian Zhang ,  Jennifer Jean Brady ,  Aaron Ken Sato ,  Wen-Chen Yeh ,  Yang Li ,  Teppei Yamaguchi

IPC: C07K14/705 ,  A61K47/65 ,  C07K14/47 ,  C07K16/28 ,  C07K16/40 ,  C07K19/00 ,  C12N15/62

CPC classification number: C07K14/705 ,  A61K47/65 ,  C07K14/47 ,  C07K16/2851 ,  C07K16/2881 ,  C07K16/40 ,  C12N15/62 ,  C07K2317/622 ,  C07K2317/71 ,  C07K2317/75 ,  C07K2319/30

Abstract: The present disclosure provides tissue-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in targeted tissues.

公开(公告)号：US11773171B2

公开(公告)日：2023-10-03

申请号：US16954484

申请日：2018-12-19

Applicant: Surrozen Operating, Inc.

Inventor： Yang Li ,  Tom Zhiye Yuan ,  Aaron Ken Sato ,  Wen-Chen Yeh ,  Claudia Yvonne Janda ,  Tristan William Fowler ,  Helene Baribault ,  Kuo-Pao Lai ,  Liqin Xie ,  Randall J. Brezski ,  Chenggang Lu

IPC: C07K16/28 ,  C07K16/46 ,  A61K39/00

CPC classification number: C07K16/2863 ,  C07K16/468 ,  A61K2039/505 ,  C07K2317/30 ,  C07K2317/55 ,  C07K2317/569 ,  C07K2317/622 ,  C07K2317/92

Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.