公开(公告)号：US06618605B1

公开(公告)日：2003-09-09

申请号：US09391965

申请日：1999-09-08

申请人： Steven D. Wolff ,  Glenn S. Slavin ,  Thomas K. F. Foo

发明人： Steven D. Wolff ,  Glenn S. Slavin ,  Thomas K. F. Foo

IPC分类号： A61B5055

CPC分类号： G01R33/56341 ,  G01R33/4838

摘要： A method and apparatus is disclosed for MR perfusion acquisition using a notched RF saturation pulse. In acquiring such MR data, a volume of slice locations is selected in which MR data is to be acquired. Each given slice is prepared with a notched RF saturation pulse which has a stop-band between a pair of pass-bands. The stop-band is designed to not affect the spins in the next slice in which MR data is to be acquired thereby effectively increasing the TI and increasing SNR and contrast simultaneously. Since the notched saturation pulse saturates all the spins outside of the notched stop-band, the blood in the ventricular chamber is effectively saturated so that the resulting perfusion images have blood pool suppression. Additionally, the use of a 90° presaturation RF pulse provides a high level of immunity to the effects of arrhythmias or other variations in the patient's heart rate. In order to keep the stop-band, or the notch, as wide as possible to overlap the boundaries of each slice location, it is preferable to interleave the acquisition of slice locations.

摘要翻译： 公开了一种使用缺口RF饱和脉冲进行MR灌注采集的方法和装置。 在获取这样的MR数据时，选择要获取MR数据的片段位置量。 每个给定的切片用具有一对通带之间的阻带的缺口RF饱和脉冲来制备。 阻带被设计成不影响将要获取MR数据的下一个切片中的自旋，从而有效地增加TI并同时增加SNR和对比度。 由于缺口饱和脉冲饱和了缺口挡带外的所有旋转，所以心室内的血液被有效地饱和，使得所得到的灌注图像具有血液池抑制。 另外，90°预饱和RF脉冲的使用可以提供高度的抗心律失常作用或其他变化对患者心率的影响。 为了使阻带或陷波尽可能地保持与每个切片位置的边界重叠，优选地切片切片位置的获取。

公开(公告)号：US07283862B1

公开(公告)日：2007-10-16

申请号：US10063832

申请日：2002-05-16

申请人： Glenn S. Slavin ,  Thomas K. F. Foo

发明人： Glenn S. Slavin ,  Thomas K. F. Foo

IPC分类号： A61B5/05

CPC分类号： G01R33/563 ,  G01R33/4835 ,  G01R33/4838 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56366

摘要： The present invention includes a method and apparatus to perform rapid multi-slice MR imaging without ECG gating or requiring breath-holding that is capable of renal profusion analysis and angiographic screening. An ungated interleaved pulse sequence is applied in rapid succession, followed by a delay interval. The ungated interleaved pulse sequence is repeatedly played out with the predefined delay interval between each application of the pulse sequence. The resulting images provide not only a series of temporal phases of contrast-enhanced blood uptake for renal profusion analysis, but also provide enough dynamic range to include angiographic screening of the renal arteries.

摘要翻译： 本发明包括一种方法和装置，用于执行无需ECG门控的快速多切片MR成像或需要能够进行肾分泌分析和血管造影筛选的呼吸保持。 以快速连续的方式施加非啮合交错脉冲序列，然后是延迟间隔。 在脉冲序列的每个应用之间以预定的延迟间隔重复播放非同步交织的脉冲序列。 所得到的图像不仅提供用于肾分泌分析的对比度增强的血液摄取的一系列时间阶段，而且还提供足够的动态范围以包括肾动脉的血管造影筛查。

公开(公告)号：US5926022A

公开(公告)日：1999-07-20

申请号：US838554

申请日：1997-04-09

申请人： Glenn S. Slavin ,  Stephen J. Riederer

发明人： Glenn S. Slavin ,  Stephen J. Riederer

IPC分类号： G01R33/561 ,  G01V3/175

CPC分类号： G01R33/5615 ,  G01R33/5616 ,  G01R33/56554

摘要： A bipolar, phase-encoding, pre-phaser pulse is employed in each shot of a multi-shot EPI pulse sequence to smooth the phase-encoding gradient first moment throughout the scan. The first moment of the pre-phaser pulse is calculated for each shot in the scan and is played out at the beginning of each shot after the RF excitation.

摘要翻译： 在多次EPI脉冲序列的每个镜头中采用双相，相位编码的预相位脉冲，以平滑整个扫描中的相位编码梯度的第一时刻。 对于扫描中的每个镜头计算预相位脉冲的第一时刻，并且在RF激发之后的每次拍摄开始时播放。

公开(公告)号：US20080081986A1

公开(公告)日：2008-04-03

申请号：US11536917

申请日：2006-09-29

申请人： Glenn S. Slavin

发明人： Glenn S. Slavin

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  G01R33/4828 ,  G01R33/5607 ,  G01R33/5616 ,  G01R33/5617

摘要： A method for generating a magnetic resonance image includes a series of inversion and saturation pulses, in which the pulses null the MRI signal from both fat and a second tissue for a single MRI acquisition. An inversion pulse is used to provide a null point for the second tissue. A pair of fat-selective saturation and inversion pulses are used to null the MRI signal from fat at approximately the same time as the second tissue reaches its null point. The saturation pulse is used to create a known state for the fat magnetization, allowing the flip angle of the fat-selective inversion pulse to be determined such that the null point of fat approximately coincides with the null point of the second tissue.

摘要翻译： 用于产生磁共振图像的方法包括一系列反转和饱和脉冲，其中脉冲将来自脂肪和第二组织的MRI信号从单次MRI采集中清除。 反转脉冲用于为第二组织提供零点。 在第二组织达到其零点的同时，使用一对脂肪选择性饱和度和反转脉冲来消除来自脂肪的MRI信号。 饱和脉冲用于产生用于脂肪磁化的已知状态，从而允许确定脂肪选择性反转脉冲的翻转角，使得脂肪的零点大致与第二组织的零点重合。