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公开(公告)号：US20240252822A1
公开(公告)日：2024-08-01
申请号：US18629088
申请日：2024-04-08
CPC分类号： A61N1/36036 , A61N1/0456 , A61N1/36031 , A61N1/36034
摘要： In an illustrative embodiment, systems and methods for inhibiting, reducing or eliminating motion sickness using a neuromodulation device configured to be worn on a subject's head and a controller configured to deliver therapeutic stimulation pulses for providing motion sickness therapy involve delivering, by the controller, a first series of stimulation pulses to first electrode(s) positioned on or near the subject's ear in a first tissue region to modulate peripheral activity, and delivering, by the controller, a second series of stimulation pulses to second electrode(s) positioned on or near the subject's ear in a second tissue region t to modulate one or more areas in the subject's brain stem.
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公开(公告)号：US20220305260A1
公开(公告)日：2022-09-29
申请号：US17832437
申请日：2022-06-03
IPC分类号： A61N1/36
摘要： In an illustrative embodiment, methods and systems for attenuating effect(s) associated with reduction or cessation of substance use by an individual include providing a neurostimulation delivery system including a neurostimulation device having a first portion including at first electrode configured to electrically stimulate branch(s) of the auriculotemporal nerve, and a second portion including a second electrode configured to electrically stimulate auricular branch(es) of the vagus nerve, and a pulse generator including circuitry configured to deliver therapeutic stimulation pulses to the first and second electrodes. Methods and systems include positioning the neurostimulation device for administration of the neurostimulation treatment, whereby the first electrode is disposed on, over or adjacent to branch(s) of the auriculotemporal nerve, and the second electrode is disposed on, over or adjacent to auricular branch(es) of the vagus nerve, and administering the neurostimulation treatment.
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3.发明公开公开(公告)号：US20230149703A1
公开(公告)日：2023-05-18
申请号：US18094313
申请日：2023-01-06
CPC分类号： A61N1/0456 , A61N1/0476 , A61N1/36017 , A61N1/36034
摘要： In an illustrative embodiment, systems and methods for treating stress and/or for improving alertness in a subject using neurostimulation therapy include placing first electrode(s) on, over, or adjacent to an auricular branch of the vagus nerve, placing second electrode(s) on, over or adjacent to an auriculotemporal nerve, and delivering therapeutic stimulation pulses via the first electrode(s) and the second electrode(s) by delivering a first series of stimulation pulses to the first electrode(s), the first series configured to increase activity in neural medullary structure(s), and delivering a second series of stimulation pulses to the second electrode(s), the second series configured to increase activity in neural structures within the Trigeminocervical Complex.
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公开(公告)号：US10967182B2
公开(公告)日：2021-04-06
申请号：US16846220
申请日：2020-04-10
摘要： Systems and methods for reducing pulmonary inflammation and/or increasing bronchial compliance in a patient utilize transcutaneous stimulation of neural structures in a region of an ear of a patient delivered by an auricular stimulation device having an in-ear component with a first electrode disposed in a patient's ear and an earpiece component with a second electrode placed around the auricle. A pulse generator may control delivery of therapy by delivering both a first series of stimulation pulses to the first electrode for stimulating a first neural structure(s) and a second series of stimulation pulses to the second electrode for stimulating second neural structure(s). The first and second electrodes are in non-piercing contact with tissue on and/or surrounding the ear. The systems and methods may be used to treat viral or bacteria infections, such as SARS, MERS, or COVID-19.
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公开(公告)号：US20240285944A1
公开(公告)日：2024-08-29
申请号：US18583160
申请日：2024-02-21
CPC分类号： A61N1/3606 , A61N1/0456 , A61N1/36017 , A61N1/36171
摘要： In an illustrative embodiment, methods and system for increasing coagulation potential and/or triggering a higher platelet activation rate in a subject via auricular neurostimulation include contacting skin of the subject with one or more therapeutic electrodes, each electrode positioned in a respective region of nerve structures of the auriculotemporal nerve (ATN), nerve structures connected to the ATN, nerve structures of the auricular branch of the vagus nerve (ABVN), or nerve structures connected to the ABVN, applying, to the electrodes, one or more stimulation patterns.
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6.发明申请公开(公告)号：US20210213286A1
公开(公告)日：2021-07-15
申请号：US17219712
申请日：2021-03-31
摘要： Systems and methods for treating cognitive dysfunction and/or depression using transcutaneous auricular neurostimulation therapy may include positioning a wearable neurostimulation device about the ear of the patient, connecting the wearable neurostimulation device, to a pulse generator, and delivering a first series of stimulation pulses to at least one first electrode, the first series being configured to increase monoamine neurotransmitter availability, and delivering a second series of stimulation pulses to at least one second electrode, the second series being configured to upregulate opioid receptor agonists.
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公开(公告)号：US20200238085A1
公开(公告)日：2020-07-30
申请号：US16846220
申请日：2020-04-10
摘要： Systems and methods for reducing pulmonary inflammation and/or increasing bronchial compliance in a patient utilize transcutaneous stimulation of neural structures in a region of an ear of a patient delivered by an auricular stimulation device having an in-ear component with a first electrode disposed in a patient's ear and an earpiece component with a second electrode placed around the auricle. A pulse generator may control delivery of therapy by delivering both a first series of stimulation pulses to the first electrode for stimulating a first neural structure(s) and a second series of stimulation pulses to the second electrode for stimulating second neural structure(s). The first and second electrodes are in non-piercing contact with tissue on and/or surrounding the ear. The systems and methods may be used to treat viral or bacteria infections, such as SARS, MERS, or COVID-19.
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公开(公告)号：US12017068B2
公开(公告)日：2024-06-25
申请号：US18202834
申请日：2023-05-26
CPC分类号： A61N1/36036 , A61N1/0456 , A61N1/36031 , A61N1/36034
摘要： In an illustrative embodiment, systems and methods for providing antiemetic therapy through neuromodulation include positioning a first electrode against or at least partially into a first tissue region on or surrounding a subject's ear such that the first electrode is on, over, or adjacent to one or more first neural structures, positioning a second electrode against or at least partially into a second tissue region on or surrounding the ear such that the second electrode is on, over, or adjacent to one or more second neural structures, delivering a first series of stimulation pulses to the first electrode for modulating peripheral activity via modulating central neural autonomic structures, and delivering a second series of stimulation pulses to the second electrode for increasing availability of central norepinephrine.
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9.发明公开公开(公告)号：US20230414928A1
公开(公告)日：2023-12-28
申请号：US17750109
申请日：2022-05-20
CPC分类号： A61N1/0456 , A61N1/3603 , A61N1/36036
摘要： In an illustrative embodiment, systems and methods for treating stress and/or for improving alertness in a subject using neurostimulation therapy include placing first electrode(s) on, over, or adjacent to an auricular branch of the vagus nerve, placing second electrode(s) on, over or adjacent to an auriculotemporal nerve, and delivering therapeutic stimulation pulses via the first electrode(s) and the second electrode(s) by delivering a first series of stimulation pulses to the first electrode(s), the first series configured to increase activity in neural medullary structure(s), and delivering a second series of stimulation pulses to the second electrode(s), the second series configured to increase activity in neural structures within the Trigeminocervical Complex.
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公开(公告)号：US11623088B2
公开(公告)日：2023-04-11
申请号：US17832437
申请日：2022-06-03
摘要： In an illustrative embodiment, methods and systems for attenuating effect(s) associated with reduction or cessation of substance use by an individual include providing a neurostimulation delivery system including a neurostimulation device having a first portion including a first electrode configured to electrically stimulate auricular branch(es) of the vagus nerve, and a second portion including a second electrode configured to electrically stimulate branch(es) of the auriculotemporal nerve, and a pulse generator including circuitry configured to deliver therapeutic stimulation pulses to the first and second electrodes. Methods and systems include positioning the neurostimulation device for administration of the neurostimulation treatment, whereby the first electrode is disposed on, over or adjacent to auricular branch(es) of the vagus nerve, and the second electrode is disposed on, over or adjacent to branch(es) of the auriculotemporal nerve, and administering the neurostimulation treatment.
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