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1.发明授权Coordination complex of diaminocyclohexaneplatinum(II) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same 有权二氨基环己烷（II）与含有（羧酸）链段的嵌段共聚物和包含其的抗肿瘤剂的配位络合物公开(公告)号：US08012463B2
公开(公告)日：2011-09-06
申请号：US10581914
申请日：2004-12-08
Applicant: Kazunori Kataoka , Nobuhiro Nishiyama , Horacio Cabral , Soichiro Okazaki
Inventor： Kazunori Kataoka , Nobuhiro Nishiyama , Horacio Cabral , Soichiro Okazaki
IPC: A61K31/74
CPC classification number: A61K45/06 , A61K9/1075 , C07F15/0093 , C08G85/002 , Y02P20/55
Abstract: A coordinate complex of diaminocyclohexane platinum (II) with a block copolymer comprising a poly(ethylene glycol) segment and a poly(carboxylic acid) segment is provided. The complex can be effectively used in treatments for tumors, in particular malignant tumors.
Abstract translation: 提供二氨基环己烷铂（II）与包含聚（乙二醇）链段和聚（羧酸）链段的嵌段共聚物的配位络合物。 该复合物可以有效地用于治疗肿瘤，特别是恶性肿瘤。
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Patent Agency Ranking
2.发明申请Coordination complex of diaminocyclohexaneplatinum(II) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same 有权二氨基环己烷（II）与含有（羧酸）链段的嵌段共聚物和包含其的抗肿瘤剂的配位络合物公开(公告)号：US20070148125A1
公开(公告)日：2007-06-28
申请号：US10581914
申请日：2004-12-08
Applicant: Kazunori Kataoka , Nobuhiro Nishiyama , Horacio Cabral , Soichiro Okazaki
Inventor： Kazunori Kataoka , Nobuhiro Nishiyama , Horacio Cabral , Soichiro Okazaki
IPC: A61K31/785 , C08F20/00
CPC classification number: A61K45/06 , A61K9/1075 , C07F15/0093 , C08G85/002 , Y02P20/55
Abstract: A coordinate complex of diaminocyclohexane platinum (II) with a block copolymer comprising a poly(ethylene glycol) segment and a poly(carboxylic acid) segment is provided. The complex can be effectively used in treatments for tumors, in particular malignant tumors.
Abstract translation: 提供二氨基环己烷铂（II）与包含聚（乙二醇）链段和聚（羧酸）链段的嵌段共聚物的配位络合物。 该复合物可以有效地用于治疗肿瘤，特别是恶性肿瘤。
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3.发明授权公开(公告)号：US08758603B2
公开(公告)日：2014-06-24
申请号：US13129703
申请日：2009-11-19
Applicant: Soichiro Okazaki
Inventor： Soichiro Okazaki
CPC classification number: A61M1/3472 , A61M1/3496 , A61M1/3643 , A61M1/3646 , A61M1/365 , A61M1/3652
Abstract: A plasma purifying device is provided that is capable of recovering blood and plasma remaining within the plasma purifying device easily and without risk of coagulation, following completion of plasma purification therapy. The plasma purifying device has a control unit controls flow rates of the air pump and a plasma pump so that a pressure of the filtration side space of the plasma separator is higher than a pressure of the blood side space while delivering blood to the blood side space of the plasma separator by continuing to operate a blood pump without stopping following completion of plasma purification and then delivers plasma remaining in a filtration side space of a plasma separator to a blood side space of the plasma separator or to a plasma circuit by supplying air from an air pump.
Abstract translation: 提供了一种等离子体净化装置，其能够在完成血浆纯化治疗后容易地回收血浆和血浆净化装置中剩余的血浆和血浆，而没有凝结的危险。 等离子体净化装置具有控制单元，其控制空气泵和等离子体泵的流量，使得等离子体分离器的过滤侧空间的压力高于血液侧空间的压力，同时将血液输送到血液侧空间 通过在血浆纯化完成后继续操作血液泵而不停止等离子体分离器的操作，然后将等离子体分离器的过滤侧空间中剩余的血浆输送到等离子体分离器的血液侧空间，或者通过从等离子体回路供给空气 一个气泵。
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公开(公告)号：US20100087771A1
公开(公告)日：2010-04-08
申请号：US12527270
申请日：2008-02-14
Applicant: Atsushi Karakama , Soichiro Okazaki
Inventor： Atsushi Karakama , Soichiro Okazaki
IPC: A61M1/14
CPC classification number: A61M1/34 , A61M1/16 , A61M1/1605 , A61M1/1643 , A61M1/3431 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3455 , A61M2205/12 , A61M2205/3334 , A61M2205/3393
Abstract: Provision of a blood purification system comprising a blood purification tubing and a blood purification apparatus particularly suitable for use in continuous hemofiltration in which in the treatment of a patient with renal disease, multiple organ failure, and the like, the amount of water removed from the patient and the amount of supply to the patient can be more accurately controlled, and in which preparation operation is easy. A blood purification system comprising a blood purification tubing and a blood purification apparatus wherein the soft tubes of flow paths connecting a first planar panel and a second planar panel, and the location of the soft tubes are selected to satisfy a formula of a predetermined condition.
Abstract translation: 提供血液净化系统，其包括血液净化管和特别适合用于连续血液滤过的血液净化装置，其中在治疗患有肾脏疾病，多器官功能衰竭等的患者中，从 可以更准确地控制患者的供给量，并且准备操作容易。 一种血液净化系统，其包括血液净化管和血液净化装置，其中选择连接第一平面面板和第二平面面板的流路的软管和软管的位置以满足预定条件的公式。
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公开(公告)号：US08202241B2
公开(公告)日：2012-06-19
申请号：US12527270
申请日：2008-02-14
Applicant: Atsushi Karakama , Soichiro Okazaki
Inventor： Atsushi Karakama , Soichiro Okazaki
CPC classification number: A61M1/34 , A61M1/16 , A61M1/1605 , A61M1/1643 , A61M1/3431 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3455 , A61M2205/12 , A61M2205/3334 , A61M2205/3393
Abstract: Provision of a blood purification system comprising a blood purification tubing and a blood purification apparatus particularly suitable for use in continuous hemofiltration in which in the treatment of a patient with renal disease, multiple organ failure, and the like, the amount of water removed from the patient and the amount of supply to the patient can be more accurately controlled, and in which preparation operation is easy. A blood purification system comprising a blood purification tubing and a blood purification apparatus wherein the soft tubes of flow paths connecting a first planar panel and a second planar panel, and the location of the soft tubes are selected to satisfy a formula of a predetermined condition.
Abstract translation: 提供血液净化系统，其包括血液净化管和特别适合用于连续血液滤过的血液净化装置，其中在治疗患有肾脏疾病，多器官功能衰竭等的患者中，从 可以更准确地控制患者的供给量，并且准备操作容易。 一种血液净化系统，其包括血液净化管和血液净化装置，其中选择连接第一平面面板和第二平面面板的流路的软管和软管的位置以满足预定条件的公式。
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6.发明申请公开(公告)号：US20110284467A1
公开(公告)日：2011-11-24
申请号：US13129703
申请日：2009-11-09
Applicant: Soichiro Okazaki
Inventor： Soichiro Okazaki
IPC: B01J39/00
CPC classification number: A61M1/3472 , A61M1/3496 , A61M1/3643 , A61M1/3646 , A61M1/365 , A61M1/3652
Abstract: A plasma purifying device is provided that is capable of recovering blood and plasma remaining within the plasma purifying device easily and without risk of coagulation, following completion of plasma purification therapy. The plasma purifying device has a control unit controls flow rates of the air pump and a plasma pump so that a pressure of the filtration side space of the plasma separator is higher than a pressure of the blood side space while delivering blood to the blood side space of the plasma separator by continuing to operate a blood pump without stopping following completion of plasma purification and then delivers plasma remaining in a filtration side space of a plasma separator to a blood side space of the plasma separator or to a plasma circuit by supplying air from an air pump.
Abstract translation: 提供了一种等离子体净化装置，其能够在完成血浆纯化治疗后容易地回收血浆和血浆净化装置中剩余的血浆和血浆，而没有凝结的危险。 等离子体净化装置具有控制单元，其控制空气泵和等离子体泵的流量，使得等离子体分离器的过滤侧空间的压力高于血液侧空间的压力，同时将血液输送到血液侧空间 通过在血浆纯化完成后继续操作血液泵而不停止操作血液泵，然后将等离子体分离器的过滤侧空间中剩余的血浆输送到血浆分离器的血液侧空间或等离子体回路中， 一个气泵。
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