公开(公告)号：US20230039492A1

公开(公告)日：2023-02-09

申请号：US17973055

申请日：2022-10-25

申请人： Scanogen Inc.

发明人： Alfredo Andres Celedon ,  Saravana Radha Krishna Murthy ,  Zhiguang Xu ,  Danielle Elise Schultz ,  Troy Allen Horn

IPC分类号： C12Q1/6816 ,  G01N33/543 ,  G01N27/327 ,  G01N27/74 ,  G01N27/414

摘要： The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.

公开(公告)号：US20190112641A1

公开(公告)日：2019-04-18

申请号：US16217253

申请日：2018-12-12

申请人： Scanogen Inc.

发明人： Alfredo Andres Celedon ,  Saravana Radha Krishna Murthy ,  Zhiguang Xu ,  Danielle Elise Schultz ,  Troy Allen Horn

IPC分类号： C12Q1/6816 ,  G01N33/543

摘要： The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.

公开(公告)号：US10179930B2

公开(公告)日：2019-01-15

申请号：US15033629

申请日：2015-02-05

申请人： Scanogen Inc.

发明人： Alfredo Andres Celedon ,  Saravana Radha Krishna Murthy ,  Zhiguang Xu ,  Danielle Elise Schultz ,  Troy Allen Horn

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C12Q1/6816 ,  G01N33/543

摘要： The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.

公开(公告)号：US11505818B2

公开(公告)日：2022-11-22

申请号：US16217253

申请日：2018-12-12

申请人： Scanogen Inc.

发明人： Alfredo Andres Celedon ,  Saravana Radha Krishna Murthy ,  Zhiguang Xu ,  Danielle Elise Schultz ,  Troy Allen Horn

IPC分类号： C07K16/00 ,  C07H21/02 ,  C12Q1/6816 ,  G01N33/543 ,  G01N27/327 ,  G01N27/74 ,  G01N27/414

摘要： The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.

公开(公告)号：US20160258003A1

公开(公告)日：2016-09-08

申请号：US15033629

申请日：2015-02-05

申请人： SCANOGEN INC.

发明人： Alfredo Andres Celedon ,  Saravana Radha Krishna Murthy ,  Zhiguang Xu ,  Danielle Elise Schultz ,  Troy Allen Horn

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6816 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54373

摘要： The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.

摘要翻译： 本申请涉及用于使用由靶和第一和第二探针形成的复合物检测样品中的一种或多种靶分析物的检测单元和方法，其中所述复合物包括细长区域，耦合到第一探针的颗粒， 以及耦合到第二探针的固体支持物。 目标分析物的特异性结合可以通过测量颗粒的位移来区别于颗粒的非特异性结合。