公开(公告)号：US09775900B2

公开(公告)日：2017-10-03

申请号：US15469602

申请日：2017-03-27

Applicant: Sanochemia Pharmazeutika AG

Inventor： Stefan Welzig ,  Beate Kälz ,  József Gungl ,  Klaus Gerdes ,  Werner Frantsits ,  Christina Abrahamsberg

IPC: A61K9/00 ,  A61K41/00 ,  A61K31/121 ,  A61K36/38 ,  C07C50/36 ,  C07C50/00

CPC classification number: A61K41/00 ,  A61K9/0009 ,  A61K9/08 ,  A61K31/121 ,  A61K36/38 ,  A61K41/0057 ,  A61K47/32 ,  A61K49/0021 ,  A61K49/0054 ,  A61K49/0071 ,  C07C50/00 ,  C07C50/36

Abstract: In the early detection of cancer, in particular bladder cancer, a photodynamic diagnosis uses, as a photosensitizer, a formulation that contains sodium hypericinate that is bonded to polyvinylpyrrolidone or complexed with polyvinylpyrrolidone.

公开(公告)号：US10143751B2

公开(公告)日：2018-12-04

申请号：US14878515

申请日：2015-10-08

Applicant: Sanochemia Pharmazeutika AG

Inventor： Stefan Welzig ,  Gregor Medinger ,  Beate Kalz ,  Jozsef Gungl ,  Klaus Gerdes ,  Werner Frantsits ,  Christina Abrahamsberg

IPC: A61K41/00 ,  A61K47/58 ,  A61K47/60 ,  A61K9/00 ,  A61K9/08 ,  A61K9/19 ,  A61K47/32 ,  A61N5/06

Abstract: Photodynamic therapy of tumors such as bladder tumors includes photosensitizing with a photosensitizer that is a complex or a compound of hypericin and a polymeric complexing agent. The photosensitizer is formed from an alkali salt of hypericin and the polymeric complexing agent. The alkali salt of hypericin is a sodium salt or a potassium salt. The complexing agent is a polyethylene glycol or a poly-N-vinyl amide.

公开(公告)号：US10265397B2

公开(公告)日：2019-04-23

申请号：US15805491

申请日：2017-11-07

Applicant: Sanochemia Pharmazeutika AG

Inventor： Stefan Welzig ,  Gregor Medinger ,  Beate Kálz ,  József Gungl ,  Klaus Gerdes ,  Werner Frantsits ,  Christina Abrahamsberg

IPC: A61K41/00 ,  A61K47/58 ,  A61K47/60 ,  A61K9/00 ,  A61K9/08 ,  A61K9/19 ,  A61K47/32 ,  A61N5/06

Abstract: Photodynamic therapy of tumors such as bladder tumors includes photosensitizing with a photosensitizer that is a complex or a compound of hypericin and a polymeric complexing agent. The photosensitizer is formed from an alkali salt of hypericin and the polymeric complexing agent. The alkali salt of hypericin is a sodium salt or a potassium salt. The complexing agent is a polyethylene glycol or a poly-N-vinyl amide.

公开(公告)号：US10201609B2

公开(公告)日：2019-02-12

申请号：US15805664

申请日：2017-11-07

Applicant: Sanochemia Pharmazeutika AG

Inventor： Stefan Welzig ,  Gregor Medinger ,  Beate Kälz ,  József Gungl ,  Klaus Gerdes ,  Werner Frantsits ,  Christina Abrahamsberg

IPC: A61K41/00 ,  A61K47/58 ,  A61K47/60 ,  A61K9/00 ,  A61K9/08 ,  A61K9/19 ,  A61K47/32 ,  A61N5/06

Abstract: Photodynamic therapy of tumors such as bladder tumors includes photosensitizing with a photosensitizer that is a complex or a compound of hypericin and a polymeric complexing agent. The photosensitizer is formed from an alkali salt of hypericin and the polymeric complexing agent. The alkali salt of hypericin is a sodium salt or a potassium salt. The complexing agent is a polyethylene glycol or a poly-N-vinyl amide.

公开(公告)号：US09629932B2

公开(公告)日：2017-04-25

申请号：US14878573

申请日：2015-10-08

Applicant: Sanochemia Pharmazeutika AG

Inventor： Stefan Welzig ,  Beate Kalz ,  Jozsef Gungl ,  Klaus Gerdes ,  Werner Frantsits ,  Christina Abrahamsberg

IPC: A61K9/00 ,  A61K49/00

CPC classification number: A61K41/00 ,  A61K9/0009 ,  A61K9/08 ,  A61K31/121 ,  A61K36/38 ,  A61K41/0057 ,  A61K47/32 ,  A61K49/0021 ,  A61K49/0054 ,  A61K49/0071 ,  C07C50/00 ,  C07C50/36

Abstract: In the early detection of cancer, in particular bladder cancer, a photodynamic diagnosis uses, as a photosensitizer, a formulation that contains sodium hypericinate that is bonded to polyvinylpyrrolidone or complexed with polyvinylpyrrolidone.