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公开(公告)号：US09637541B2
公开(公告)日：2017-05-02
申请号：US14556911
申请日：2014-12-01
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hyung-Chan Kim , Kyung Eun Kim , Yoon Sook Lee , Mi Young Cho
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: An anti-c-Met/anti-Ang2 bispecific antibody, a composition including the anti-c-Met/anti-Ang2 bispecific antibody, and a method of preventing and/or treating a cancer in a subject including administering the anti-c-Met/anti-Ang2 bispecific antibody to the subject.
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公开(公告)号：US20150210761A1
公开(公告)日：2015-07-30
申请号：US14606441
申请日：2015-01-27
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun Kim , Yoon Sook Lee , Sang Yeul Han , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Seok Kyun Kim
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/3046 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/6872 , G01N2333/515 , G01N2500/04
Abstract: An Ang2 specific antibody, a method of preventing and/or treating a disease related to the activation and/or overproduction (overexpression) of Ang2 by administering the antibody to a subject, and a method of screening a candidate substance for diagnosing, preventing, or treating a disease related to activation or overproduction of Ang2.
Abstract translation: Ang2特异性抗体，通过向受试者施用抗体来预防和/或治疗与激动和/或过量产生（过表达）Ang2有关的疾病的方法，以及筛选候选物质的方法，用于诊断，预防或/ 治疗与Ang2的活化或过量产生相关的疾病。
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公开(公告)号：US10934350B2
公开(公告)日：2021-03-02
申请号：US16004622
申请日：2018-06-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/22 , G01N33/68 , C07K14/705 , C07K14/515 , A61K38/00
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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公开(公告)号：US09994632B2
公开(公告)日：2018-06-12
申请号：US14721591
申请日：2015-05-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/00 , C07K16/28 , C07K16/22 , A61K39/395 , G01N33/68 , C07K14/705 , C07K14/515 , A61K39/00 , A61K38/00
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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公开(公告)号：US09725513B2
公开(公告)日：2017-08-08
申请号：US14336812
申请日：2014-07-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Hoon Lee , Hyung-Chan Kim , Sang Yeul Han , Seok Kyun Kim , Kyung Eun Kim
CPC classification number: C07K16/2863 , C07K14/71 , C07K2317/73 , C07K2317/92 , C07K2318/20 , C07K2319/30
Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
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Patent Agency Ranking
6.发明授权Peptide for inhibition of binding between angiopoietin-2 and integrin and use thereof 有权抑制血管生成素-2与整联蛋白结合的肽及其用途公开(公告)号：US09193768B2
公开(公告)日：2015-11-24
申请号：US14058069
申请日：2013-10-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sang Yeul Han , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang-Hoon Lee , Hyo Seon Lee
IPC: C07K14/00 , C07K14/515 , A61K38/00
CPC classification number: A61K38/1891 , A61K38/00 , C07K14/00 , C07K14/001 , C07K14/515 , C07K2319/30 , C07K2319/70
Abstract: There are provided an angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
Abstract translation: 提供了血管生成素-2（Ang2）衍生的肽，多肽和肽复合物，以及抑制Ang2和整联蛋白之间结合的方法，以及预防和/或治疗Ang2的激活或Ang2的结合引起的疾病 和使用肽，多肽和肽复合物的整联蛋白。
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公开(公告)号：US20150037343A1
公开(公告)日：2015-02-05
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun KIM , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/622 , C07K2317/76 , C07K2317/92 , G01N2500/04 , Y02A50/412
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
Abstract translation: Ang2特异性抗体，抑制血管生成的方法或使用该抗体治疗与Ang2的活化和/或过量产生有关的疾病的方法，以及用于诊断与Ang2的活化和/或过量产生有关的疾病的组合物，包括 抗体。
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公开(公告)号：US10246511B2
公开(公告)日：2019-04-02
申请号：US15667424
申请日：2017-08-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Hoon Lee , Hyung-Chan Kim , Sang Yeul Han , Seok Kyun Kim , Kyung Eun Kim
Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
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公开(公告)号：US10047154B2
公开(公告)日：2018-08-14
申请号：US14447242
申请日：2014-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sang Yeul Han , Kwang Hoon Lee , Kyung Eun Kim , Chung Ho Kim , Yong In Kim , Hyung-Chan Kim , Yoon Sook Lee , Hyo Seon Lee
IPC: A61K39/395 , A61K39/00 , C07K16/00 , C07K16/22
Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
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公开(公告)号：US20150010572A1
公开(公告)日：2015-01-08
申请号：US14322343
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Yoon Sook LEE , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Sang Yeul Han
CPC classification number: C07K16/22 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2800/7014
Abstract: Provided are an anti-Ang-2 antibody or antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang-2), related compositions and pharmaceutical compositions, and methods for using such compositions and pharmaceutical compositions.
Abstract translation: 提供特异性结合血管发生诱导因子促血管生成素-2（Ang-2），相关组合物和药物组合物的抗Ang-2抗体或其抗原结合片段，以及使用这些组合物和药物组合物的方法。
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