公开(公告)号：US20150140014A1

公开(公告)日：2015-05-21

申请号：US14081886

申请日：2013-11-15

Applicant: Samsung Electronics Co., Ltd.

Inventor： Seung Hyun LEE ,  Geun Woong Kim ,  Kyung Ah Kim ,  Hye Won Park ,  Ho Yeong Song ,  Young Mi Oh ,  Saet Byoul Lee ,  Ji Min Lee ,  Kwang Ho Cheong ,  Yun Ju Jeong ,  Mi Young Cho ,  Jae Hyun Choi ,  Yun Jeong Song ,  Yoon Aa Choi

IPC: C07K14/71 ,  A61K31/437 ,  A61K31/44 ,  A61K39/395 ,  A61K31/517

CPC classification number: A61K31/437 ,  A61K31/44 ,  A61K31/517 ,  A61K39/3955 ,  A61K39/39558 ,  C07K16/2863 ,  C07K2317/24 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2319/30 ,  C12N5/163 ,  A61K2300/00

Abstract: A method for prevention or treatment of a cancer, comprising co-administering (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib or a combination thereof, to a subject in need thereof, and a pharmaceutical composition comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib, or a combination thereof are provided.

Abstract translation: 一种预防或治疗癌症的方法，包括共同给予（a）抗c-Met抗体或其抗原结合片段，和（b）拉帕替尼，替罗非尼，伏马拉净或其组合中的至少一种， （a）抗c-Met抗体或其抗原结合片段，和（b）拉帕替尼，替罗非尼，伏马拉净或其组合中的至少一种提供给药物组合物 。

公开(公告)号：US09717715B2

公开(公告)日：2017-08-01

申请号：US14081886

申请日：2013-11-15

Applicant: Samsung Electronics Co., Ltd.

Inventor： Seung Hyun Lee ,  Geun Woong Kim ,  Kyung Ah Kim ,  Hye Won Park ,  Ho Yeong Song ,  Young Mi Oh ,  Saet Byoul Lee ,  Ji Min Lee ,  Kwang Ho Cheong ,  Yun Ju Jeong ,  Mi Young Cho ,  Jae Hyun Choi ,  Yun Jeong Song ,  Yoon Aa Choi

IPC: A61K39/395 ,  A61K31/437 ,  A61K31/517 ,  A61K31/44 ,  C07K16/28 ,  C12N5/16

CPC classification number: A61K31/437 ,  A61K31/44 ,  A61K31/517 ,  A61K39/3955 ,  A61K39/39558 ,  C07K16/2863 ,  C07K2317/24 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2319/30 ,  C12N5/163 ,  A61K2300/00

Abstract: A method for prevention or treatment of a cancer, comprising co-administering (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib or a combination thereof, to a subject in need thereof, and a pharmaceutical composition comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib, or a combination thereof are provided.

公开(公告)号：US20140154251A1

公开(公告)日：2014-06-05

申请号：US14081917

申请日：2013-11-15

Applicant: Samsung Electronics Co., Ltd.

Inventor： Seung Hyun LEE ,  Geun Woong Kim ,  Kyung Ah Kim ,  Hye Won Park ,  Ho Yeong Song ,  Young Mi Oh ,  Saet Byoul Lee ,  Ji Min Lee ,  Kwang Ho Cheong ,  Yun Ju Jeong ,  Mi Young Cho ,  Jae Hyun Choi ,  Yun Jeong Song ,  Yoon Aa Choi

IPC: C07K16/28

CPC classification number: C07K16/2863 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/52 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/92

Abstract: An anti-c-Met antibody or antibody fragment and pharmaceutical composition comprising same, as well as a method for preventing and treating cancer by administering the antibody to a subject are provided.

Abstract translation: 提供了抗c-Met抗体或抗体片段及包含其的药物组合物，以及通过向受试者施用抗体来预防和治疗癌症的方法。