公开(公告)号：US20240043899A1

公开(公告)日：2024-02-08

申请号：US18320389

申请日：2023-05-19

Applicant: SYNVITROBIO, INC.

Inventor： Zachary Z. Sun ,  Abel C. Chiao ,  Dan E. Robertson ,  Louis E. Metzger ,  Richard Mansfield ,  Kelly S. Trego

IPC: C12P21/02 ,  C12N15/85

CPC classification number: C12P21/02 ,  C12N15/85 ,  C12Y207/07006

Abstract: Provided herein, in one aspect, is a composition for in vitro transcription and translation, comprising: a treated cell lysate derived from one or more host cells such as bacteria, archaea, plant or animal; a plurality of supplements for gene transcription and translation; an energy recycling system for providing and recycling adenosine triphosphate (ATP); and one or more exogenous additives. Methods for making and using the same are also provided.