公开(公告)号：US09518028B2

公开(公告)日：2016-12-13

申请号：US14901721

申请日：2013-11-18

Applicant: SUVEN LIFE SCIENCES LIMITED

Inventor： Udaya Bhaskara Rao Siripalli ,  Veera Reddy Arava ,  Rajendiran Chinnapillai ,  Anji Reddy Middekadi ,  Naresh Raju Makaraju ,  Venkateswarlu Jasti

IPC: C07D239/42 ,  C07F7/18

CPC classification number: C07D239/42 ,  C07F7/1804 ,  C07F7/188

Abstract: The present invention relates to process for the preparation of 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-6-heptenoic acid calcium having formula (I). The compound of formula (I) has adopted name “Rosuvastatin Calcium”. The present invention is also related to novel intermediates of formula (4) and formula (5) used in preparation of formula (I), and process of their preparation.

公开(公告)号：US20180105609A1

公开(公告)日：2018-04-19

申请号：US15559976

申请日：2015-05-06

Applicant: Suven Life Sciences Limited

Inventor： Udaya Bhaskara Rao Siripalli ,  Lakshmi Narasimhulu Gorentla ,  Veera Reddy Arava ,  Mohana Rao Manam ,  Venkateswarlu Jasti

IPC: C08B31/18 ,  C08L3/10 ,  C08B30/18

CPC classification number: C08B31/18 ,  C08B30/18 ,  C08L3/10

Abstract: The present invention provides an improved process for the preparation of Ferric carboxymaltose (FCM) complex. In this process the oxidation of maltodextrins are carried out by using an organic hypo halite in the presence of a catalyst and a phase transfer catalyst and later complex formation with ferric salt or ferric hydroxide or iron hydroxide maltodextrin complex.