公开(公告)号：US20140187581A1

公开(公告)日：2014-07-03

申请号：US13982486

申请日：2012-01-05

Applicant: SUVEN LIFE SCIENCES LIMITED

Inventor： Ramakrishna Nirogi ,  Abdul Rasheed Mohammed ,  Suresh Yarlagadda ,  Srinivasa Rao Ravella ,  Anil Karbhari Shinde ,  Ramasastri Kamphampati ,  Praveen Kumar Roayapalley ,  Pradeep Jayarajan ,  Gopinadh Bhyrapuneni ,  Sriramachandra Murthy Patnala ,  Jyothsna Ravula ,  Venkateswarlu Jasti

IPC: C07D413/14 ,  C07D413/06

CPC classification number: A61K31/454 ,  A61K31/4245 ,  C07D413/06 ,  C07D413/14

Abstract: The present invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their pharmaceutically acceptable salts. The compounds of formula (I) are useful in the treatment of various disorders that are related to 5-HT4 receptors.

Abstract translation: 本发明涉及式（I）的新化合物及其药学上可接受的盐和组合物。 本发明还涉及制备上述新化合物及其药学上可接受的盐的方法。 式（I）化合物可用于治疗与5-HT4受体相关的各种疾病。

公开(公告)号：US12122779B2

公开(公告)日：2024-10-22

申请号：US17285432

申请日：2019-10-16

Applicant: SUVEN LIFE SCIENCES LIMITED

Inventor： Ramakrishna Nirogi ,  Abdul Rashee Mohammed ,  Anil Karbhari Shinde ,  Srinivasa Rao Ravella ,  Ramkumar Subramanian ,  Venkateswarlu Jasti

IPC: C07D487/04 ,  A61K45/06 ,  A61P1/00 ,  A61P25/00

CPC classification number: C07D487/04 ,  A61K45/06 ,  A61P1/00 ,  A61P25/00

Abstract: The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt(s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of such compounds. (I)