公开(公告)号：US20240043800A1

公开(公告)日：2024-02-08

申请号：US18264521

申请日：2022-02-04

Applicant: SUNGKWANG MEDICAL FOUNDATION

Inventor： Ji Yoon LEE ,  Ah Reum LEE ,  Jung Eun PARK

IPC: C12N5/078

CPC classification number: C12N5/0634 ,  C12N2501/165 ,  C12N2501/115 ,  C12N2501/145 ,  C12N2501/14 ,  C12N2501/105 ,  C12N2501/125 ,  C12N2501/2305 ,  C12N2501/2307 ,  C12N2501/155 ,  C12N2501/2306 ,  C12N2501/2315 ,  C12N2500/38 ,  C12N2501/22 ,  C12N2501/998

Abstract: Provided is a method of differentiating a pluripotent stem cell-derived hemogenic endothelial cell into a lymphoid lineage blood cell, enabling a hemogenic endothelial cell to be cultured for a long period of time so as to be induced into a lymphoid lineage blood cell, thereby facilitating induction of generation of immune cells such as T cells, B cells, and NK cells.