公开(公告)号：US3919318A

公开(公告)日：1975-11-11

申请号：US47799574

申请日：1974-06-10

Applicant: STANFORD RESEARCH INST

Inventor： ACTON EDWARD M ,  LEROM MICHAEL W ,  STONE HERBERT

IPC: C07C251/48 ,  A23L27/30 ,  C07C45/51 ,  C07C45/56 ,  C07C47/42 ,  C07C67/00 ,  C07C239/00 ,  C07C251/44 ,  C07C131/08

CPC classification number: C07C249/08 ,  A23L27/30 ,  C07C45/44 ,  C07C45/513 ,  C07C45/562 ,  C07C47/42 ,  C07C251/36 ,  C07C47/47 ,  C07C49/753

Abstract: New compounds 4-methyl-1,4-cyclohexadiene-1-carboxaldehyde synoxime, 4-methoxymethyl-1,4-cyclohexadiene-1-carboxaldehyde synoxime, and 4-(1-methoxyethyl)-1,4-cyclohexadiene-1-carboxaldehyde syn-oxime, as well as the compound 1,4-cyclohexadiene-1carboxaldehyde syn-oxime, are found to have a high degree of sweetness which is accompanied by very little off-taste. The compounds have good stability even in acid solution. They give no evidence of toxicity and can be employed in foods and beverages as synthetic sweetening ingredients.

公开(公告)号：US3699132A

公开(公告)日：1972-10-17

申请号：US3699132D

申请日：1970-09-02

Applicant: STANFORD RESEARCH INST

Inventor： ACTON EDWARD M ,  LEAFFER MORRIS A ,  STONE HERBERT

IPC: C07D303/36 ,  C07D1/00 ,  C07D1/06

CPC classification number: C07D303/36

Abstract: 8,9-Epoxyperillartine optical isomers having good sweetness and no or moderately low bitter aftertaste characteristics, along with an increased solubility in water as compared with the corresponding perillartine precursor isomers. These epoxy derivatives are also free of the undesirable gingery-licorice taste of perillartine. The new compounds give no evidence of toxicity and can be employed in foods as synthetic sweetening ingredients.