公开(公告)号：US20160144128A1

公开(公告)日：2016-05-26

申请号：US14905129

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann

IPC分类号： A61M5/315

CPC分类号： A61M5/31568 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/3155 ,  A61M5/31583 ,  A61M2005/3126

摘要： The present disclosure relates to a counting mechanism (2) for a drug delivery device (1) comprising a first counting member (4) arranged for displaying a counted number and being biased to move in a first rotational direction and a connecting member (5) having a dose setting position and a dose dispensing position, wherein, in the dose setting position, the connecting member (5) impedes a rotation of the first counting member (4) in the first rotational direction, and wherein, in the dose dispensing position, the connecting member (5) permits the first counting member (4) to rotate in the first rotational direction.

摘要翻译： 本公开涉及一种用于药物输送装置（1）的计数机构（2），包括：第一计数构件（4），被布置成用于显示计数并被偏置以沿第一旋转方向移动;以及连接构件（5） 具有剂量设定位置和剂量分配位置，其中，在所述剂量设定位置，所述连接部件（5）阻止所述第一计数部件（4）沿所述第一旋转方向旋转，并且其中，在所述剂量分配位置 ，连接构件（5）允许第一计数构件（4）沿第一旋转方向旋转。

公开(公告)号：US20160166773A1

公开(公告)日：2016-06-16

申请号：US14905153

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/315

CPC分类号： A61M5/31525 ,  A61M2005/3126

摘要： An indicator for a delivery device comprising a belt (71) having marks (73) for dose indication and/or status indication.

摘要翻译： 一种用于输送装置的指示器，包括具有用于剂量指示和/或状态指示的标记（73）的皮带（71）。

公开(公告)号：US10441724B2

公开(公告)日：2019-10-15

申请号：US14904736

申请日：2014-07-17

申请人： Sanofi

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/31

摘要： A drive mechanism for a delivery device is presented. The drive mechanism comprises a housing (24) and a piston rod (6) having a longitudinal axis (x) and a piston rod feature (17). The drive mechanism further comprises a drive member (1) being movable with respect to the housing (24). The drive member (1) comprises a drive feature (15). The drive feature (15) is selectively engageable with the piston rod feature (17) by the radial displacement of the drive member (1) with respect to the piston rod (6). When the drive member (1) is in the first position, the drive member (1) is disengaged from the piston rod (6), and when the drive member (1) is in the second position, the drive feature (15) is engaged with the piston rod feature (17). When the drive member (1) moves distally with respect to the housing (24), said distal movement is transferred to the piston rod (6) such that the piston rod (6) moves distally with respect to the housing (24).

公开(公告)号：US20160158456A1

公开(公告)日：2016-06-09

申请号：US14904736

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/315

CPC分类号： A61M5/31578 ,  A61M5/20 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31535 ,  A61M5/31541 ,  A61M5/31543 ,  A61M5/31553 ,  A61M5/31561 ,  A61M5/3157 ,  A61M5/31573 ,  A61M5/31583 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/586

摘要： A drive mechanism for a delivery device is presented. The drive mechanism comprises a housing (24) and a piston rod (6) having a longitudinal axis (x) and a piston rod feature (17). The drive mechanism further comprises a drive member (1) being movable with respect to the housing (24). The drive member (1) comprises a drive feature (15). The drive feature (15) is selectively engageable with the piston rod feature (17) by the radial displacement of the drive member (1) with respect to the piston rod (6). When the drive member (1) is in the first position, the drive member (1) is disengaged from the piston rod (6), and when the drive member (1) is in the second position, the drive feature (15) is engaged with the piston rod feature (17). When the drive member (1) moves distally with respect to the housing (24), said distal movement is transferred to the piston rod (6) such that the piston rod (6) moves distally with respect to the housing (24).

摘要翻译： 提出了一种用于输送装置的驱动机构。 驱动机构包括具有纵向轴线（x）和活塞杆特征（17）的壳体（24）和活塞杆（6）。 驱动机构还包括可相对于壳体（24）移动的驱动构件（1）。 驱动构件（1）包括驱动特征（15）。 通过驱动构件（1）相对于活塞杆（6）的径向位移，驱动特征（15）可选择性地与活塞杆特征（17）接合。 当驱动部件（1）处于第一位置时，驱动部件（1）从活塞杆（6）脱离，当驱动部件（1）处于第二位置时，驱动部件（15）为 与活塞杆特征（17）接合。 当驱动构件（1）相对于壳体（24）向远侧移动时，所述远端运动被传递到活塞杆（6），使得活塞杆（6）相对于壳体（24）向远侧移动。

公开(公告)号：US20160158451A1

公开(公告)日：2016-06-09

申请号：US14904746

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/31 ,  A61M11/00

CPC分类号： A61M5/3146 ,  A61M5/1452 ,  A61M5/31511 ,  A61M5/31515 ,  A61M5/31583 ,  A61M11/007 ,  A61M15/009 ,  A61M2005/1402

摘要： The priming configuration comprises a piston rod (1), a bung (2), which is provided to be driven by the piston rod, and a movable element (5), which is engaged with the piston rod. The movable element is arranged to be movable in a predefined direction (10) with respect to the piston rod by a user of the drug delivery device. A movement of the movable element in the predefined direction advances the piston rod in a further direction (11), providing a priming of the drug delivery device before use. The predefined direction may especially be transverse to the further direction, and the further direction may especially be directed from the piston rod towards the bung (2). A gap (12) or clearance between the piston rod (1) and the bung (2) can thus be removed, and the stiction of the bung (2) to the cartridge (3) can be reduced.

摘要翻译： 起动构造包括活塞杆（1），设置成由活塞杆驱动的栓（2）和与活塞杆接合的可动元件（5）。 可移动元件布置成可以由药物输送装置的使用者相对于活塞杆在预定方向（10）上移动。 可移动元件在预定方向上的运动使得活塞杆在另一方向（11）上前进，在使用前提供了药物输送装置的起动。 预定的方向可以特别地横向于另外的方向，并且进一步的方向可以特别地从活塞杆朝向栓（2）。 因此，可以移除活塞杆（1）和塞子（2）之间的间隙（12）或间隙，并且可以减小塞子（2）到墨盒（3）的粘性。

公开(公告)号：US20160144121A1

公开(公告)日：2016-05-26

申请号：US14905222

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/315

CPC分类号： A61M5/3155 ,  A61M5/20 ,  A61M5/3146 ,  A61M5/31551 ,  A61M5/31553 ,  A61M5/31558 ,  A61M5/31561 ,  A61M5/31568 ,  A61M5/3157 ,  A61M5/31578 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583

摘要： A drive mechanism for a delivery device or a positioning mechanism comprising a rod (5), a rotatable cam member (9), and a follower member (6) being coupled to the cam member (9) in such a manner that a rotation of the cam member (9) is transferred to a reciprocating movement of the follower member (6) or a part thereof (7), the follower member (6) being coupled to the rod (5) via a ratchet mechanism (62, 64) in such a manner that the reciprocating movement of the follower member (6) or the part thereof (7) drives the rod (5).

摘要翻译： 一种用于输送装置或定位机构的驱动机构，包括杆（5），可旋转凸轮构件（9）和从动构件（6），其以这样的方式联接到所述凸轮构件（9） 凸轮构件（9）被转移到从动构件（6）或其一部分（7）的往复运动，从动构件（6）通过棘轮机构（62,64）联接到杆（5） 从动构件（6）或其一部分（7）的往复运动驱动杆（5）。

公开(公告)号：US10279118B2

公开(公告)日：2019-05-07

申请号：US14905078

申请日：2014-07-17

申请人： Sanofi

发明人： Tom Oakley ,  Matt Schumann ,  Mark Pawulski

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/31

摘要： A drive mechanism (11) for a delivery device comprising a drive member (17) for driving a piston rod (13); a moveable dose setting member (19, 35) being disengaged from the drive member (17) in a dose setting state and being moveable in a drive direction in a dose delivery state, wherein the dose setting member (19, 35) engages with the drive member (17) in the dose delivery state in such a manner that the movement of the dose setting member (19, 35) in the drive direction is transferred to the drive member (17); and a spring member (21) being coupled to the dose setting member (19, 35) in such a manner that the movement of the dose setting member (19, 35) in a setting direction loads the spring member (21) in the dose setting state, the spring force of the loaded spring member (21) driving the dose setting member (19, 35) in the drive direction in the dose delivery state.

公开(公告)号：US10137249B2

公开(公告)日：2018-11-27

申请号：US14904746

申请日：2014-07-17

申请人： Sanofi

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/31 ,  A61M11/00 ,  A61M5/315 ,  A61M15/00 ,  A61M5/145 ,  A61M5/14

摘要： The priming configuration comprises a piston rod (1), a bung (2), which is provided to be driven by the piston rod, and a movable element (5), which is engaged with the piston rod. The movable element is arranged to be movable in a predefined direction (10) with respect to the piston rod by a user of the drug delivery device. A movement of the movable element in the predefined direction advances the piston rod in a further direction (11), providing a priming of the drug delivery device before use. The predefined direction may especially be transverse to the further direction, and the further direction may especially be directed from the piston rod towards the bung (2). A gap (12) or clearance between the piston rod (1) and the bung (2) can thus be removed, and the stiction of the bung (2) to the cartridge (3) can be reduced.

公开(公告)号：US09987433B2

公开(公告)日：2018-06-05

申请号：US14905446

申请日：2014-07-17

申请人： Sanofi

发明人： Tom Oakley ,  Matt Schumann ,  Stuart Milne

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/31

CPC分类号： A61M5/31541 ,  A61M5/20 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31535 ,  A61M5/31543 ,  A61M5/31553 ,  A61M5/31561 ,  A61M5/3157 ,  A61M5/31573 ,  A61M5/31583 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/586

摘要： An assembly for a drug delivery device (200) is presented which comprises a housing (24) having a proximal end (25) and a distal end (26), a cartridge, a plunger (19) which is movably retained in the cartridge (14) and a piston rod (6). The assembly further comprises a rod displacement feature (33). The assembly is configured such that, in an initial state of the assembly, the piston rod (6) and the rod displacement feature (33) are arranged such that movement of the rod displacement feature (33) from the first position to the second position is transferred to the piston rod (6) such that the piston rod (6) is moved with respect to the cartridge (14) and the assembly is switched from the initial state to a primed state. In the primed state, movement of the rod displacement feature (33) from the first position to the second position is not transferred to the piston rod (6).

公开(公告)号：US20160158453A1

公开(公告)日：2016-06-09

申请号：US14905147

申请日：2014-07-17

申请人： SANOFI

发明人： Tom Oakley ,  Matt Schumann ,  Mark Pawulski

IPC分类号： A61M5/315

CPC分类号： A61M5/31526 ,  A61M5/20 ,  A61M5/31535 ,  A61M5/31536 ,  A61M5/31551 ,  A61M5/31553 ,  A61M5/31558 ,  A61M5/31563 ,  A61M5/31578 ,  A61M5/31583 ,  A61M2005/3126

摘要： A drive mechanism (11) for a delivery device comprising —a drive member (17) for driving a piston rod (13); —a moveable dose setting member (19, 35) being decoupled from the drive member (17) in a dose setting state; the dose setting member (19, 35) being moveable in a drive direction in a dose delivery state, wherein the movement of the dose setting member (19, 35) is transferred to the drive member (17); and —a dose control means (49) being coupled to the dose setting member (19, 35) by a rack-and-pinion means (51, 67) in such a manner that the movement of the dose setting member (19, 35) is transferred to a movement of the dose control means (49), wherein the movement of the dose setting member (19, 35) is stopped when the dose control means (49) reaches an end position.

摘要翻译： 一种用于输送装置的驱动机构（11），包括：用于驱动活塞杆（13）的驱动构件（17）。 - 可动剂量设定构件（19,35）在剂量设定状态下与所述驱动构件（17）分离; 所述剂量设定部件（19,35）能够在剂量输送状态下沿驱动方向移动，其中所述剂量设定部件（19,35）的移动被传递到所述驱动部件（17）。 和 - 剂量控制装置（49），其通过齿条和小齿轮装置（51,67）以剂量设定构件（19,35）的移动方式联接到剂量设定构件（19,35） ）被转移到剂量控制装置（49）的移动，其中当剂量控制装置（49）到达结束位置时，剂量设定构件（19,35）的移动停止。