公开(公告)号：US20180127362A1

公开(公告)日：2018-05-10

申请号：US15639135

申请日：2017-06-30

申请人： Reviva Pharmaceuticals, Inc.

发明人： Laxminarayan BHAT ,  Kouacou ADIEY ,  Seema Rani BHAT

IPC分类号： C07C317/28 ,  C07C211/29 ,  C07C323/32 ,  C07C323/25 ,  C07C217/74 ,  C07C317/18 ,  C07C211/27 ,  C07C217/08

CPC分类号： C07C317/28 ,  C07C211/27 ,  C07C211/29 ,  C07C217/08 ,  C07C217/74 ,  C07C317/18 ,  C07C317/50 ,  C07C323/25 ,  C07C323/32 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07D207/09 ,  C07D211/34

摘要： The present invention provides novel phenylcycloalkylmethylamine derivatives, and methods of preparing phenylcycloalkylmethylamine derivatives. The present invention also provides methods of using phenylcycloalkylmethylamine derivatives and compositions of phenylcycloalkylmethylamine derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.

公开(公告)号：US20180071299A1

公开(公告)日：2018-03-15

申请号：US15643782

申请日：2017-07-07

申请人： Reviva Pharmaceuticals, Inc.

发明人： Laxminarayan BHAT ,  Marc CANTILLON ,  Seema Rani BHAT

IPC分类号： A61K31/538 ,  A61K9/00

CPC分类号： A61K31/538 ,  A61K9/0053 ,  A61K31/496 ,  A61K31/5415

摘要： The present invention provides a method of using arylpiperazine derivatives for treating psychosis associated with Parkinson's disease. The method comprises a step of administering to a patient in need thereof an effective amount of a compound of Formula 1, which is an arylpiperazine derivative.

公开(公告)号：US20160115121A1

公开(公告)日：2016-04-28

申请号：US14986267

申请日：2015-12-31

申请人： Reviva Pharmaceuticals, Inc.

发明人： Laxminarayan BHAT ,  Kouacou ADIEY ,  Seema Rani BHAT

IPC分类号： C07C317/28 ,  C07C211/29 ,  C07C217/74 ,  C07C211/27

CPC分类号： C07C317/28 ,  C07C211/27 ,  C07C211/29 ,  C07C217/08 ,  C07C217/74 ,  C07C317/18 ,  C07C317/50 ,  C07C323/25 ,  C07C323/32 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07D207/09 ,  C07D211/34

摘要： The present invention provides novel phenylcycloalkylmethylamine derivatives, and methods of preparing phenylcycloalkylmethylamine derivatives. The present invention also provides methods of using phenylcycloalkylmethylamine derivatives and compositions of phenylcycloalkylmethylamine derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.

摘要翻译： 本发明提供新的苯基环烷基甲基胺衍生物，以及制备苯基环烷基甲基胺衍生物的方法。 本发明还提供使用苯基环烷基甲基胺衍生物和苯基环烷基甲胺衍生物的组合物的方法。 本发明化合物的药物组合物可用于治疗和/或预防肥胖和肥胖相关并发症适应症和抑郁症和抑郁症相关并发症的适应症。

公开(公告)号：US20140024679A1

公开(公告)日：2014-01-23

申请号：US13731670

申请日：2012-12-31

申请人： Reviva Pharmaceuticals, Inc.

发明人： Laxminarayan BHAT ,  Kouacou ADIEY ,  Seema Rani BHAT

IPC分类号： C07D211/34 ,  C07C317/50 ,  C07D207/09 ,  C07C211/27

CPC分类号： C07C317/28 ,  C07C211/27 ,  C07C211/29 ,  C07C217/08 ,  C07C217/74 ,  C07C317/18 ,  C07C317/50 ,  C07C323/25 ,  C07C323/32 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07D207/09 ,  C07D211/34

摘要： The present invention provides novel phenylcycloalkylmethylamine derivatives, and methods of preparing phenylcycloalkylmethylamine derivatives. The present invention also provides methods of using phenylcycloalkylmethylamine derivatives and compositions of phenylcycloalkylmethylamine derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.

摘要翻译： 本发明提供新的苯基环烷基甲基胺衍生物，以及制备苯基环烷基甲基胺衍生物的方法。 本发明还提供使用苯基环烷基甲基胺衍生物和苯基环烷基甲胺衍生物的组合物的方法。 本发明化合物的药物组合物可用于治疗和/或预防肥胖和肥胖相关并发症适应症和抑郁症和抑郁症相关并发症的适应症。

公开(公告)号：US20130231386A1

公开(公告)日：2013-09-05

申请号：US13866905

申请日：2013-04-19

申请人： REVIVA PHARMACEUTICALS, INC.

发明人： Laxminarayan BHAT ,  Seema Rani BHAT

IPC分类号： C07C271/16 ,  C07C229/34

CPC分类号： C07C229/34 ,  C07C229/14 ,  C07C271/16 ,  C07C2601/04

摘要： The present invention provides novel cycloalkylmethylamine analogs, and methods of preparing cycloalkylmethylamine analogs. The present invention also provides methods of using cycloalkylmethylamine analogs and compositions of cycloalkylmethylamine analogs. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications.

摘要翻译： 本发明提供新的环烷基甲胺类似物，以及制备环烷基甲胺类似物的方法。 本发明还提供了使用环烷基甲胺类似物和环烷基甲胺类似物的组合物的方法。 本发明化合物的药物组合物可有利地用于治疗和/或预防肥胖和肥胖相关并发症的适应症。