-
1.发明申请公开(公告)号：US20180182603A1
公开(公告)日：2018-06-28
申请号：US15388589
申请日：2016-12-22
发明人： Hartwig Schmidt , Michael E. Patterson , Stefan R. Lukow , Kenneth R. Gonthier , Hanh T. Lai , Vibha Mishra
摘要： The present disclosure is directed to methods and systems for calibration, calibration verification, and sensitivity checks for a detector. The methods and systems include calibrating a detector by releasing at least one calibrant from at least one calibrant chamber in flow communication with the detector. The systems and methods further include verifying the calibration by releasing at least one verification substance from at least one verification chamber in flow communication with the detector. The systems and methods further include checking a sensitivity of the detector by releasing at least one sensitivity substance from at least one sensitivity chamber in flow communication with the detector.
-
公开(公告)号：US10651024B2
公开(公告)日：2020-05-12
申请号：US16031087
申请日：2018-07-10
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US10049868B2
公开(公告)日：2018-08-14
申请号：US15370947
申请日：2016-12-06
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US20190204274A1
公开(公告)日：2019-07-04
申请号：US16222971
申请日：2018-12-17
发明人： Gary A. Eiceman , Marlen R. Menlyadiev , Hartwig Schmidt , Stefan R. Lukow , Peter Fowler , Gyoungil Lee
CPC分类号： G01N27/624 , H01J49/0031 , H01J49/0409
摘要： A system for multi-stage differential mobility spectrometer (multi-stage DMS) and the method of operating and using the same are described. Ions produced in an ionization source are introduced into the separation region of multi-stage DMS, which includes at least two DMS stages. Each DMS stage is configured to generate separation and compensation fields to characterize, separate, or select ion species. The separation region further includes ion alteration stages which are placed between various adjacent stages of multi-stage DMS. Alteration of ions can be both chemical and physical. Ions which are separated, altered, and selectively passed by all DMS stages of multi-stage DMS are then measured or further characterized by the Faraday plate detectors or a mass spectrometer.
-
公开(公告)号：US20180158665A1
公开(公告)日：2018-06-07
申请号：US15370947
申请日：2016-12-06
CPC分类号： H01J49/401 , G01N27/622 , H01J49/0045
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US20200027713A1
公开(公告)日：2020-01-23
申请号：US16415105
申请日：2019-05-17
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US20190139752A1
公开(公告)日：2019-05-09
申请号：US16031087
申请日：2018-07-10
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US20200286723A1
公开(公告)日：2020-09-10
申请号：US16841929
申请日：2020-04-07
摘要： An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
-
公开(公告)号：US10707063B2
公开(公告)日：2020-07-07
申请号：US15388589
申请日：2016-12-22
发明人： Hartwig Schmidt , Michael E. Patterson , Stefan R. Lukow , Kenneth R. Gonthier , Hanh T. Lai , Vibha Mishra
摘要： The present disclosure is directed to methods and systems for calibration, calibration verification, and sensitivity checks for a detector. The methods and systems include calibrating a detector by releasing at least one calibrant from at least one calibrant chamber in flow communication with the detector. The systems and methods further include verifying the calibration by releasing at least one verification substance from at least one verification chamber in flow communication with the detector. The systems and methods further include checking a sensitivity of the detector by releasing at least one sensitivity substance from at least one sensitivity chamber in flow communication with the detector.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.013 秒)
