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公开(公告)号：US20240255391A1
公开(公告)日：2024-08-01
申请号：US18528088
申请日：2023-12-04
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Gregory J. Sherwood , Justin Theodore Nelson
CPC classification number: G01N1/2226 , G01N27/22 , G16H15/00 , G16H20/00 , G16H50/20 , G16H50/30 , G01N2001/2229 , G01N2027/222
Abstract: Embodiments herein include a method for detecting a health condition of a subject. The method can include obtaining a biological sample from the subject and placing it into a container having a headspace surrounding the biological sample. The method can include contacting a gas from the headspace with a chemical sensor element, the chemical sensor element including one or more discrete graphene varactors. The method can include sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set. Other embodiments are also included herein.
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公开(公告)号：US11921096B2
公开(公告)日：2024-03-05
申请号：US17012642
申请日：2020-09-04
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Gregory J. Sherwood , Justin Theodore Nelson , Raia Colette Finc , Michael J. Lyden , John M. Darst , Michael Mathias Freking
IPC: G01N33/00 , G01N27/447 , G01N27/70
CPC classification number: G01N33/0008 , G01N27/44765 , G01N27/70 , G01N33/0034
Abstract: Embodiments herein relate to breath analysis system. In an embodiment, a gas measurement device is included having a housing defining an interior volume. The housing can include a fluid ingress port, a fluid egress port, a bottom wall, and a circuit board disposed within the interior volume. The circuit board can include a first side and a second side, where the first side of the circuit board faces inward toward the interior volume. The circuit board can include a plurality of gas sensors disposed on the first side of the circuit board and a plurality of conductive pads disposed on the second side of the circuit board, wherein a plurality of electrical contacts contact the conductive pads when the circuit board is seated within the housing. Other embodiments are also included herein.
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公开(公告)号：US20230184741A1
公开(公告)日：2023-06-15
申请号：US17941364
申请日：2022-09-09
Inventor： Gregory Kermit Peterson , Justin Theodore Nelson , Gregory J. Sherwood
IPC: G01N33/497 , G01N1/22 , G01N27/22
CPC classification number: G01N33/497 , G01N1/2226 , G01N27/227 , G01N33/4972 , G01N2001/2244
Abstract: Embodiments herein include a method for detecting a brain condition in a subject. The method can include obtaining a breath sample from the subject and contacting it with a chemical sensor element, where the chemical sensor element includes a plurality of discrete graphene varactors. The method can include sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set and classifying the sample data set into one or more preestablished brain condition classifications. Other embodiments are also included herein.
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公开(公告)号：US20220125325A1
公开(公告)日：2022-04-28
申请号：US17520339
申请日：2021-11-05
Inventor： Arthur Guy Erdman , Gregory J. Sherwood , Gregory Kermit Peterson , Justin Theodore Nelson , Michael Mathias Freking
IPC: A61B5/0205 , A61B5/00
Abstract: Embodiments herein include a breath sampling mask, systems, and related methods. In an embodiment, a breath sensing system is included. The breath sensing system can include a breath sampling mask. The breath sampling mask can include a mask housing configured to cover a portion of the face of a patient. The mask housing can define a breath receiving chamber. The breath sampling mask can include a chemical sensor element in fluid communication with the breath sampling mask, where the chemical sensor element can include a plurality of discrete binding detectors. The chemical sensor element can interface with a breath sample collected through the breath sampling mask. Other embodiments are also included herein.
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公开(公告)号：US20190331661A1
公开(公告)日：2019-10-31
申请号：US16393177
申请日：2019-04-24
IPC: G01N33/497 , G01N27/22 , G01N27/12
Abstract: Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a it-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein.
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Patent Agency Ranking
公开(公告)号：US20220291198A1
公开(公告)日：2022-09-15
申请号：US17707214
申请日：2022-03-29
IPC: G01N33/497 , G01N27/12 , G01N27/22
Abstract: Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a π-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein.
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公开(公告)号：US11442056B2
公开(公告)日：2022-09-13
申请号：US16656159
申请日：2019-10-17
Inventor： Gregory Kermit Peterson , Justin Theodore Nelson , Gregory J. Sherwood
IPC: G01N33/497 , G01N1/22 , G01N27/22
Abstract: Embodiments herein include a method for detecting a brain condition in a subject. The method can include obtaining a breath sample from the subject and contacting it with a chemical sensor element, where the chemical sensor element includes a plurality of discrete graphene varactors. The method can include sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set and classifying the sample data set into one or more preestablished brain condition classifications. Other embodiments are also included herein.
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公开(公告)号：US20240319152A1
公开(公告)日：2024-09-26
申请号：US18585358
申请日：2024-02-23
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Gregory J. Sherwood , Justin Theodore Nelson , Raia Colette Finc , Michael J. Lyden , John M. Darst , Michael Mathias Freking
IPC: G01N33/00 , G01N27/447 , G01N27/70
CPC classification number: G01N33/0008 , G01N27/44765 , G01N27/70 , G01N33/0034
Abstract: Embodiments herein relate to breath analysis system. In an embodiment, a gas measurement device is included having a housing defining an interior volume. The housing can include a fluid ingress port, a fluid egress port, a bottom wall, and a circuit board disposed within the interior volume. The circuit board can include a first side and a second side, where the first side of the circuit board faces inward toward the interior volume. The circuit board can include a plurality of gas sensors disposed on the first side of the circuit board and a plurality of conductive pads disposed on the second side of the circuit board, wherein a plurality of electrical contacts contact the conductive pads when the circuit board is seated within the housing. Other embodiments are also included herein.
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公开(公告)号：US11867596B2
公开(公告)日：2024-01-09
申请号：US17707214
申请日：2022-03-29
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
IPC: G01N33/497 , G01N27/12 , G01N27/22
CPC classification number: G01N33/497 , G01N27/125 , G01N27/227 , G01N2610/00
Abstract: Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a π-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein.
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公开(公告)号：US20230393087A1
公开(公告)日：2023-12-07
申请号：US18144506
申请日：2023-05-08
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Gregory J. Sherwood , Justin Theodore Nelson , Steven Koester
CPC classification number: G01N27/021 , G01N27/221 , G01N27/227 , G01N33/0036
Abstract: Embodiments herein include a kinetic response system for measuring analyte presence on a chemical sensor element. The chemical sensor element includes one or more discrete binding detectors, each discrete binding detector including a graphene varactor. The kinetic response system includes a measurement circuit having an excitation voltage generator for generating a series of excitation cycles over a time period. Each excitation cycle includes delivering a DC bias voltage to the discrete binding detectors at multiple discrete DC bias voltages across a range of DC bias voltages. The kinetic response system includes a capacitance sensor to measure capacitance of the discrete binding detectors resulting from the excitation cycles. The kinetic response system includes a controller circuit to determine the kinetics of change in at least one of a measured capacitance value and a calculated value based on the measured capacitance over the time period. Other embodiments are also included herein.
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