公开(公告)号：US20240115495A1

公开(公告)日：2024-04-11

申请号：US18368042

申请日：2023-09-14

Applicant: QNOVIA, INC.

Inventor： Mario Danek ,  Christopher Kar-Heng Cheng ,  Joseph Gene Walsh

IPC: A61K9/00 ,  A61K9/107 ,  A61K9/12 ,  A61K31/7048 ,  A61K45/06

CPC classification number: A61K9/0073 ,  A61K9/1075 ,  A61K9/12 ,  A61K31/7048 ,  A61K45/06

Abstract: An aerosolizable liquid formulation for inhalation includes one or more active pharmaceutical ingredients dissolved in a solvent. The one or more active pharmaceutical ingredients includes a vasodilator active pharmaceutical ingredient and, optionally, non-vasodilator active pharmaceutical ingredient.

公开(公告)号：US11925207B2

公开(公告)日：2024-03-12

申请号：US18237396

申请日：2023-08-23

Applicant: QNOVIA, INC.

Inventor： Mario Danek ,  Kassie Betts ,  Ian D. Kovacevich ,  Nouphone J. Bansansine ,  Joseph Gene Walsh ,  Christopher Kar-Heng Cheng ,  Chris Breen ,  Josh Rigberg ,  Toriono Granger ,  Muawea Rawashdeh ,  Ryan Hall ,  Tonya Charles ,  Jacquelyn Coker

IPC: A24F40/42 ,  A24F40/05 ,  A24F40/10 ,  A24F40/44 ,  A24F40/485 ,  A24F40/51 ,  A24F40/60 ,  A24F40/65 ,  A24F40/95 ,  A61M15/06

CPC classification number: A24F40/42 ,  A24F40/05 ,  A24F40/10 ,  A24F40/44 ,  A24F40/485 ,  A24F40/51 ,  A24F40/60 ,  A24F40/65 ,  A24F40/95 ,  A61M15/06

Abstract: An electronic device includes a hand held base assembly that includes circuitry including memory and firmware executed by a processor or microcontroller of the circuitry; and a cartridge assembly that includes memory that is read by the firmware of the handheld base assembly. The cartridge assembly and the handheld base assembly are configured to removably couple together to define the electronic device for producing an aerosol for inhalation by a person. An enclosed air passageway is defined by the cartridge assembly and by the handheld base assembly, which isolates the airflow from the electronics of the device. The enclosed air passageway extends between the opening of the mouthpiece for taking a breath and a diaphragm of the handheld base assembly, movement of the diaphragm changing the air pressure within an enclosed interior space having a pressure sensor for trigging the pressure sensor when a breath is taken.

公开(公告)号：US12011535B2

公开(公告)日：2024-06-18

申请号：US18072656

申请日：2022-11-30

Applicant: QNOVIA, INC.

Inventor： Mario Danek ,  Ian Kovacevich ,  Andrew Heinrich ,  Christopher Kar-Heng Cheng ,  Joseph Gene Walsh

IPC: A24F40/10 ,  A24B15/167 ,  A24F40/05 ,  A24F40/42 ,  A61K9/00 ,  A61K9/107 ,  A61K9/127 ,  A61K31/00 ,  A61K31/05 ,  A61K31/352 ,  A61K31/4439 ,  A61K31/465 ,  A61K47/02 ,  A61K47/26 ,  A61M11/00 ,  B05B17/06

CPC classification number: A61M11/003 ,  A24B15/167 ,  A24F40/05 ,  A24F40/10 ,  A24F40/42 ,  A61K9/0078 ,  A61K9/1075 ,  A61K9/127 ,  A61K31/05 ,  A61K31/352 ,  A61K31/4439 ,  A61K31/465 ,  A61K31/658 ,  A61K47/02 ,  A61K47/26 ,  B05B17/0653 ,  A61M2205/0294 ,  A61M2205/12 ,  A61M2205/587 ,  A61M2205/8206

Abstract: An electronic device includes a mouthpiece, a bladder, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the bladder. The mouthpiece, the bladder, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the bladder. A liquid-filled cartridge also is disclosed for use with an electronic device for delivery of a substance into a body through respiration includes a liquid container; and a liquid contained within the container for aerosolizing and inhaling by a person using the electronic device. The liquid includes a plurality of nanoparticles in a nanoemulsion, the nanoparticles including the encapsulation of the substance to be delivered into the body through respiration. The nanoemulsion preferably is produced using a microfluidizing machine.

公开(公告)号：US20230121005A1

公开(公告)日：2023-04-20

申请号：US18072656

申请日：2022-11-30

Applicant: QNOVIA, INC.

Inventor： Mario Danek ,  Ian Kovacevich ,  Andrew Heinrich ,  Christopher Kar-Heng Cheng ,  Joseph Gene Walsh

IPC: A61M11/00 ,  A61K9/127 ,  A61K47/26 ,  A61K31/352 ,  A61K31/05 ,  A61K31/4439 ,  A61K47/02 ,  A61K9/00 ,  A24F40/10 ,  A24F40/42 ,  A24B15/167 ,  A24F40/05 ,  B05B17/06 ,  A61K9/107

Abstract: An electronic device includes a mouthpiece, a bladder, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the bladder. The mouthpiece, the bladder, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the bladder. A liquid-filled cartridge also is disclosed for use with an electronic device for delivery of a substance into a body through respiration includes a liquid container; and a liquid contained within the container for aerosolizing and inhaling by a person using the electronic device. The liquid includes a plurality of nanoparticles in a nanoemulsion, the nanoparticles including the encapsulation of the substance to be delivered into the body through respiration. The nanoemulsion preferably is produced using a microfluidizing machine.