公开(公告)号：US11371992B2

公开(公告)日：2022-06-28

申请号：US16589420

申请日：2019-10-01

Applicant: Polyvalor, Limited Partnership

Inventor： Bentolhoda Heli ,  Abdellah Ajji

IPC: G01N33/53 ,  G01N33/569 ,  G01N33/543 ,  G01N21/64 ,  G01N33/58 ,  B82Y15/00

Abstract: An assay device is provided for use in determining the presence of a target analyte in a sample. The assay device comprises a solid platform comprising a fibrous mat, the solid platform impregnated with a first FRET chromophore. An antibody-FRET chromophore conjugate is immobilized on a surface of the solid platform, wherein the antibody-FRET chromophore conjugate comprises an antibody affixed to a second FRET chromophore. The first FRET chromophore and the second FRET chromophore are selected to provide an energy transfer from one to another when located within a Förster distance with respect to each other, thereby forming a FRET donor-acceptor chromophore pair. In a further aspect, a method of detecting a target analyte in a sample is provided. In yet a further aspect, packaging sheet materials and packaging articles employing the assay device under certain conditions are provided.