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公开(公告)号：US20190144429A1
公开(公告)日：2019-05-16
申请号：US16261689
申请日：2019-01-30
申请人： Pfizer Inc.
发明人： Mark Edward Schnute , Gõran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, JR. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D403/04 , C07D487/04 , C07D471/04 , C07D417/14 , C07D413/04 , C07D407/14 , C07D401/04 , A61K31/5355 , A61K31/519 , A61K31/506 , A61K31/497 , A61K31/454
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
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公开(公告)号：US20170233371A1
公开(公告)日：2017-08-17
申请号：US15497862
申请日：2017-04-26
申请人： Pfizer Inc.
发明人： Mark Edward Schnute , Gõran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, Jr. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/14 , C07D413/14 , C07D405/14 , C07D413/04 , C07D471/04 , C07D487/04 , C07D403/04 , C07D401/04 , C07D417/14
CPC分类号： C07D401/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D401/04 , C07D403/04 , C07D405/14 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , Y02A50/406 , A61K2300/00
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
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公开(公告)号：US20160046597A1
公开(公告)日：2016-02-18
申请号：US14448220
申请日：2014-07-31
申请人： PFIZER INC.
发明人： Mark Edward Schnute , Göran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, JR. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/04 , C07D413/14 , C07D403/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D401/14 , C07D405/14
CPC分类号： C07D401/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D401/04 , C07D403/04 , C07D405/14 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , Y02A50/406 , A61K2300/00
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
摘要翻译： 本发明提供化合物，药物组合物，抑制受试者的RORγ活性和/或减少IL-17的量的方法，以及使用这些化合物和药物组合物治疗各种医学病症的方法。
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公开(公告)号：US20200039960A1
公开(公告)日：2020-02-06
申请号：US16656702
申请日：2019-10-18
申请人： Pfizer Inc.
发明人： Mark Edward Schnute , Göran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, Jr. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/14 , C07D413/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D407/14 , C07D413/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D401/04 , C07D403/04 , C07D405/14
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
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公开(公告)号：US20180282304A1
公开(公告)日：2018-10-04
申请号：US16008419
申请日：2018-06-14
申请人： Pfizer Inc.
发明人： Mark Edward Schnute , Göran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, JR. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/14 , C07D403/04 , C07D413/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D401/04 , C07D407/14 , C07D413/04 , C07D405/14 , C07D487/04 , C07D471/04 , C07D417/14
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
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公开(公告)号：US20180086736A1
公开(公告)日：2018-03-29
申请号：US15834545
申请日：2017-12-07
申请人： Pfizer Inc.
发明人： Mark Edward Schnute , Göran Mattias Wennerstål , James Robert Blinn , Neelu Kaila , James Richard Kiefer, JR. , Scot Richard Mente , Ravi G. Kurumbail , Marvin Jay Meyers , Atli Thorarensen , Li Xing , Christoph Wolfgang Zapf , Edouard Zamaratski , Andrew Christopher Flick , Peter Jones
IPC分类号： C07D401/14 , C07D487/04 , C07D413/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D401/04 , C07D407/14 , C07D413/04 , C07D405/14 , C07D403/04 , C07D471/04 , C07D417/14
CPC分类号： C07D401/14 , A61K31/454 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5355 , C07D401/04 , C07D403/04 , C07D405/14 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , Y02A50/406 , A61K2300/00
摘要： The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
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