Electrochemical detector and method for producing same
    4.
    发明授权
    Electrochemical detector and method for producing same 有权
    电化学检测器及其制造方法

    公开(公告)号:US09541518B2

    公开(公告)日:2017-01-10

    申请号:US14131522

    申请日:2012-12-12

    CPC classification number: G01N27/30 G01N27/3277 H01R43/16 Y10T29/49204

    Abstract: An electrochemical detector is an electrochemical detector for detecting a substance in a liquid by generating a redox cycle, the electrochemical detector comprising: a first working electrode having a first electrode surface, a second working electrode having a second electrode surface, and a plurality of insulating spacer particles, wherein the first and second electrode surfaces are placed so as to face each other so that an electric field is formed between the first and second electrode surfaces, and the plurality of spacer particles are placed along the first and second electrode surfaces so as to separate the first and second electrode surfaces from each other.

    Abstract translation: 电化学检测器是一种用于通过产生氧化还原循环来检测液体中的物质的电化学检测器,该电化学检测器包括:具有第一电极表面的第一工作电极,具有第二电极表面的第二工作电极和多个绝缘 间隔物颗粒,其中第一和第二电极表面被放置成彼此面对,使得在第一和第二电极表面之间形成电场,并且多个间隔物颗粒沿着第一和第二电极表面放置,以便 以将第一和第二电极表面彼此分离。

    Detection method and detection device

    公开(公告)号:US11977018B2

    公开(公告)日:2024-05-07

    申请号:US17491585

    申请日:2021-10-01

    Inventor: Satoshi Arimoto

    CPC classification number: G01N15/1031 G01N15/1429 G01N2015/144

    Abstract: A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance (for example, an antibody) having a property of specifically binding to the target substance; subjecting a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being the dielectric particle constituting the complex, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis.

    Detection method and detection device

    公开(公告)号:US12209962B2

    公开(公告)日:2025-01-28

    申请号:US17488399

    申请日:2021-09-29

    Inventor: Satoshi Arimoto

    Abstract: A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance having a property of specifically binding to the target substance; separating the complex and an unbound particle from each other in a liquid by dielectrophoresis, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance included in the separated complex by using an imaging element.

    Cocaine aptamer and method for detecting cocaine using the same

    公开(公告)号:US10179915B2

    公开(公告)日:2019-01-15

    申请号:US15601060

    申请日:2017-05-22

    Inventor: Satoshi Arimoto

    Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (CI), R-DNA-L-Fc  (CI) where R represents R1-PO4—(CH2)n1—; R1 is selected from the group consisting of a hydrocarbon group and the derivative thereof; n1 represents a natural number; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by -L1-(CH2)n2-L2-; L1 is absent or an optional linker; L2 is absent or an optional linker; n2 represents a natural number; and Fc represents a ferrocene group. The present invention provides a cocaine aptamer capable of detecting cocaine with high sensitivity.

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