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公开(公告)号：US20210197189A1
公开(公告)日：2021-07-01
申请号：US17127138
申请日：2020-12-18
申请人： Pall Corporation
摘要： A buffer management system includes a supply of concentrated buffer solution, an inline dilution skid having a manifold in fluid communication with the supply of concentrated buffer solution and a control unit configured to operate the dilution skid to selectively dilute the supply of concentrated buffer solution in the manifold with a source of water for injection (WFI), and a biocontainer assembly. The biocontainer assembly includes a biocontainer bag defining a storage volume and a fill level sensor configured to generate a fill level signal indicative of the amount of material within the storage volume of the biocontainer bag. The biocontainer bag is in fluid communication with the manifold of the dilution skid for storing diluted buffer solution therein. The fill level sensor communicates the fill level signal to the control unit of the dilution skis, which uses it to manage the operation of the dilution skid.
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公开(公告)号：US20210199484A1
公开(公告)日：2021-07-01
申请号：US17127042
申请日：2020-12-18
申请人： Pall Corporation
摘要： A biocontainer assembly includes a biocontainer bag, a support frame, and a capacitive fill level sensor. The biocontainer bag defines a storage volume. The support frame includes a shelf having a support surface disposed at an oblique angle with respect to a horizontal axis. The capacitive fill level sensor is mounted to the support surface and is configured to generate a fill level signal indicative of the amount of material within the storage volume of the biocontainer bag.
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公开(公告)号：US20210197142A1
公开(公告)日：2021-07-01
申请号：US17127070
申请日：2020-12-18
申请人： Pall Corporation
摘要： A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The manifold includes a buffer inlet line in selective fluid communication with the supply of concentrated buffer solution, a WFI inlet line in selective fluid communication with the source of WFI, and a discharge line in fluid communication with both the buffer inlet line and the WFI inlet line. The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions.
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