公开(公告)号：US20240225452A1

公开(公告)日：2024-07-11

申请号：US18415664

申请日：2024-01-18

Applicant: Provincial Health Services Authority

Inventor： Haishan ZENG ,  Michael SHORT ,  Yunxian TIAN

IPC: A61B5/00 ,  G01N21/3563 ,  G01N21/64 ,  G01N21/65

CPC classification number: A61B5/0075 ,  A61B5/0086 ,  G01N21/3563 ,  G01N21/6486 ,  G01N21/65 ,  A61B2562/0233 ,  G01N2201/08

Abstract: A system useful for in vivo and ex vivo spectroscopy comprises a water source connected to supply water through a passage to an outlet at a flow rate sufficient to issue a laminar water jet from the outlet, a light source operative to emit a light beam that is guided to a sample by the water jet, and an analysis unit connected to receive collected light that has been emitted from the sample into the water jet and operable to analyze the collected light. Some embodiments provide endoscopes with integrated light guides.

公开(公告)号：US20210059513A1

公开(公告)日：2021-03-04

申请号：US16958062

申请日：2019-01-25

Applicant: PROVINCIAL HEALTH SERVICES AUTHORITY

Inventor： Hanna Claire MCGREGOR ,  Michael SHORT ,  Haishan ZENG

IPC: A61B1/267 ,  A61B1/07 ,  A61B1/005 ,  A61B1/00 ,  A61B5/00 ,  A61L29/04

Abstract: A Raman endoscope for use in obtaining in vivo Raman spectra in the peripheral airways of the lungs and a method of constructing the Raman endoscope are disclosed. The endoscope has a tubular sheath containing a fiber bundle. The sheath has an outer diameter of less than 1.35 mm. The sheath is made of fluorinated ethylene propylene. The sheath is flexible along its length from a first end to a point along the sheath so that it can navigate sharp turns within the peripheral airways. A layer of coating covers the sheath along a terminal length and a probe tip of the fiber bundle. The terminal length extends along a length of the sheath extending from a second end opposite to the first end to the point. Terminal length is rigid to facilitate advancement of the endoscope towards the lesion of interest. Terminal length is 5 mm or less.