公开(公告)号：US20170359978A1

公开(公告)日：2017-12-21

申请号：US15536556

申请日：2015-12-10

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： FRANK TECHNOW ,  LIVIU RADU TOTIR

IPC分类号： A01H1/04 ,  G06F19/18

CPC分类号： A01H1/04 ,  G16B20/00

摘要： A Bayesian multilevel whole-genome regression model is disclosed and its prediction performance compared to that of the popular BayesA model applied to each population separately (no pooling) and to the joined data set (complete pooling). For small population sizes (e.g.,

公开(公告)号：US20240276932A1

公开(公告)日：2024-08-22

申请号：US18646067

申请日：2024-04-25

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： MARK COOPER ,  CARLOS MESSINA ,  FRANK TECHNOW ,  LIVIU RADU TOTIR

IPC分类号： A01H1/04 ,  A01K67/00 ,  C12N15/82 ,  C12Q1/6895 ,  G16B5/00 ,  G16B20/00 ,  G16B20/20 ,  G16B20/40 ,  G16B20/50 ,  G16H50/30 ,  G16H70/60

CPC分类号： A01H1/04 ,  A01K67/00 ,  C12N15/8213 ,  C12Q1/6895 ,  G16B5/00 ,  G16B20/00 ,  G16B20/20 ,  G16B20/40 ,  G16B20/50 ,  C12Q2600/13 ,  C12Q2600/156 ,  G16H50/30 ,  G16H70/60 ,  Y02A90/10

摘要： Improved molecular breeding methods include a method in which an association data set is developed by associating the phenotypes of a broad population of individuals with the individual genotypes. The association data set is used in conjunction with a growth model in order to select breeding pairs likely to generate offspring with one or more desirable traits.

公开(公告)号：US20190116747A1

公开(公告)日：2019-04-25

申请号：US16096932

申请日：2017-05-03

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： JUSTIN P GERKE ,  HEATHER RENEE SNOWGREN ERICKSON ,  FRANK TECHNOW

IPC分类号： A01H1/04 ,  G16B20/40 ,  G16B40/00 ,  C12Q1/6895

摘要： Various methods are provided for determining progeny plant genotypes from a pooled sample. The methods include genotyping marker alleles in two or more progeny plants, each resulting from a different parental cross. The methods utilize in-silico deconvolution implementing Hidden Markov Modeling to determine a probability of each possible genotype for one or more marker loci in at least one progeny plant from the genetic signal generated from the pooled samples. The present methods provide for increased efficiency in genotyping progeny plants.

公开(公告)号：US20210307274A1

公开(公告)日：2021-10-07

申请号：US17229818

申请日：2021-04-13

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： JUSTIN P GERKE ,  HEATHER RENEE SNOWGREN ERICKSON ,  FRANK TECHNOW

IPC分类号： A01H1/04 ,  C12Q1/6827 ,  G16B20/00 ,  G16B40/00 ,  G16B20/40 ,  C12Q1/6895

摘要： Various methods are provided for determining progeny plant genotypes from a pooled sample. The methods include genotyping marker alleles in two or more progeny plants, each resulting from a different parental cross. The methods utilize in-silico deconvolution implementing Hidden Markov Modeling to determine a probability of each possible genotype for one or more marker loci in at least one progeny plant from the genetic signal generated from the pooled samples. The present methods provide for increased efficiency in genotyping progeny plants.

公开(公告)号：US20170245446A1

公开(公告)日：2017-08-31

申请号：US15521816

申请日：2015-08-04

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： MARK COOPER ,  CARLOS MESSINA ,  FRANK TECHNOW ,  LIVIU RADU TOTIR

IPC分类号： A01H1/04 ,  C12Q1/68 ,  G06F19/12 ,  C12N15/82 ,  G06F19/18 ,  A01H1/02 ,  A01K67/00

CPC分类号： A01H1/04 ,  A01H1/02 ,  A01K67/00 ,  C12N15/8213 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156 ,  G06F19/3456 ,  G16B5/00 ,  G16B20/00 ,  G16H50/30 ,  Y02A90/26

摘要： Improved molecular breeding methods include a method in which an association data set is developed by associating the phenotypes of a broad population of individuals with the individual genotypes. The association data set is used in conjunction with a growth model in order to select breeding pairs likely to generate offspring with one or more desirable traits.