公开(公告)号：US11950615B2

公开(公告)日：2024-04-09

申请号：US17523683

申请日：2021-11-10

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Lawrence Arne ,  Mark Zdeblick ,  Aditya Dua ,  George Savage ,  Robert Leichner ,  Jafar Shenasa ,  Patricia Johnson ,  Raymond Schmidt ,  Zahedeh Hatamkhany ,  Veeraperumanallu Muralidharan

IPC: A23L33/10 ,  A23L33/00 ,  A23L35/00 ,  A23P20/00 ,  A23P20/10 ,  G06K7/10 ,  G06K19/07 ,  H04B5/00

CPC classification number: A23L33/10 ,  A23L33/00 ,  A23L35/00 ,  A23P20/10 ,  A23P20/19 ,  G06K7/10366 ,  G06K19/0717 ,  G06K19/0723 ,  H04B5/0031 ,  H04B5/0062 ,  A23V2002/00

Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.

公开(公告)号：US11476952B2

公开(公告)日：2022-10-18

申请号：US17062897

申请日：2020-10-05

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Mark Zdeblick ,  Andrew Thompson ,  Aleksandr Pikelny ,  Timothy L. Robertson ,  Hooman Hafezi

IPC: H04B13/00 ,  A61B5/00 ,  H01Q1/27 ,  G16H20/10 ,  H04W4/80 ,  A61B5/07 ,  A61J3/00 ,  G06K7/10 ,  A61B5/1473

Abstract: An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.

公开(公告)号：US11217342B2

公开(公告)日：2022-01-04

申请号：US15498396

申请日：2017-04-26

Applicant: Otsuka Pharmaceutical, Co., Ltd

Inventor： David O'Reilly ,  Erika Karplus ,  Andrew Thompson ,  George Savage ,  Mark Zdeblick ,  Timothy Robertson ,  Lawrence Arne ,  Yashar Behzadi ,  Gregory Moon ,  Patrick Beaulieu

IPC: A61B5/07 ,  G16H20/30 ,  G16H20/10 ,  G16H20/60 ,  A61B5/00 ,  A61B5/021 ,  G16H40/67

Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

公开(公告)号：US11197492B2

公开(公告)日：2021-12-14

申请号：US16514945

申请日：2019-07-17

Applicant: OTSUKA PHARMACEUTICAL CO. LTD.

Inventor： Lawrence Arne ,  Mark Zdeblick ,  Aditya Dua ,  George Savage ,  Robert Leichner ,  Jafar Shenasa ,  Patricia Johnson ,  Raymond Schmidt ,  Zahedeh Hatamkhany ,  Veeraperumanallu Muralidharan

IPC: A23L33/10 ,  G06K19/07 ,  A23P20/10 ,  A23P20/00 ,  A23L33/00 ,  A23L35/00 ,  H04B5/00 ,  G06K7/10

Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.

公开(公告)号：US11102038B2

公开(公告)日：2021-08-24

申请号：US16600174

申请日：2019-10-11

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Robert Fleming ,  Cherie Kushner ,  William H. McAllister ,  Mark Zdeblick

IPC: H04L27/148 ,  H04L27/00 ,  H04L27/144 ,  H04L7/04 ,  H04L25/08 ,  H04L29/06 ,  H04B1/00

Abstract: A method may comprise receiving and sampling a signal. The signal may encode a data packet. A slice may be generated and stored comprising a pair of values for each of a selected number of samples of the signal representing a correlation of the signal to reference functions in the receiver. The presence of the data packet may then be detected and the detected packet decoded from the stored slices. The generating and storing slices may be carried out as the received signal is sampled. The sampled values of the signal may be discarded as the slices are generated and stored. The slice representation of the signal can be manipulated to generate filters with flexible bandwidth and center frequency.

公开(公告)号：US20220323364A1

公开(公告)日：2022-10-13

申请号：US17741173

申请日：2022-05-10

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Hooman Hafezi ,  Timothy Robertson ,  Olivier Colliou ,  Mark Zdeblick

IPC: A61K9/20 ,  H01M10/04 ,  A61B5/00 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1473 ,  A61K49/00

Abstract: Controlled activation identifiers for use in ingestible compositions, such as pharma-informatics enabled compositions, are provided. The identifiers include a controlled activation element that provides for activation of the identifier in response to the presence of a predetermined stimulus at a target site of interest. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.

公开(公告)号：US20220189606A1

公开(公告)日：2022-06-16

申请号：US17537120

申请日：2021-11-29

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： David O'Reilly ,  Erika Karplus ,  Andrew Thompson ,  George Savage ,  Mark Zdeblick ,  Timothy Robertson ,  Lawrence Arne ,  Yashar Behzadi ,  Gregory Moon ,  Patrick Beaulieu

IPC: G16H20/30 ,  G16H20/10 ,  G16H20/60 ,  A61B5/07 ,  A61B5/00

Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

公开(公告)号：US11357730B2

公开(公告)日：2022-06-14

申请号：US16235528

申请日：2018-12-28

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Hooman Hafezi ,  Timothy Robertson ,  Olivier Colliou ,  Mark Zdeblick

IPC: A61B5/00 ,  A61K9/20 ,  H01M10/04 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1473 ,  A61K49/00 ,  A61J3/00

Abstract: Apparatuses for use with a pharmaceutically acceptable carrier. The apparatus can include a partial power source, which in turn includes electrodes or materials that are configured to generate an electrical potential upon contacting or being exposed to an ionic solution. The apparatus can further include a circuit electrically or communicatively coupled to the partial power source. The circuit can generate various types of signals, such as RF signals, when powered by the partial power source. The circuit is stably fittable to the pharmaceutically acceptable carrier. The apparatus can further include a barrier, a protective layer, or a membrane that isolates the electrodes or materials from the ionic solution and is configured to be dissolved by the ionic solution.

公开(公告)号：US20220061369A1

公开(公告)日：2022-03-03

申请号：US17523683

申请日：2021-11-10

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Lawrence Arne ,  Mark Zdeblick ,  Aditya Dua ,  George Savage ,  Robert Leichner ,  Jafar Shenasa ,  Patricia Johnson ,  Raymond Schmidt ,  Zahedeh Hatamkhany ,  Veeraperumanallu Muralidharan

IPC: A23L33/10 ,  G06K19/07 ,  A23P20/10 ,  A23P20/00 ,  A23L33/00 ,  A23L35/00 ,  H04B5/00 ,  G06K7/10

Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.