公开(公告)号：US20190145959A1

公开(公告)日：2019-05-16

申请号：US16181782

申请日：2018-11-06

Applicant: OLYMPUS CORPORATION

Inventor： Mayu OGAWA ,  Kazuhito GODA ,  Kosuke TAKAGI

IPC: G01N33/50 ,  G01N21/64

Abstract: The present invention provides a method for evaluating a protrusion-forming ability of cell spheroids, comprising step (a) of imaging a cell spheroid labeled with a fluorescent substance using a fluorescence microscope at a resolution capable of identifying individual cells, and acquiring a plane tomographic image of a fluorescence emitted from the fluorescent substance, step (b) of analyzing the plane tomographic image acquired in step (a) to determine a protrusion part of the cell spheroid, and step (c) of evaluating a protrusion-forming ability of the cell spheroid based on the protrusion part determined in step (b).