公开(公告)号：US20170096699A1

公开(公告)日：2017-04-06

申请号：US15382996

申请日：2016-12-19

Applicant: OLYMPUS CORPORATION

Inventor： Masanori ASAKURA ,  Tomonori NAGAOKA ,  Nao SHIMADA

IPC: C12Q1/37 ,  G01N33/58

CPC classification number: C12Q1/37 ,  G01N33/582 ,  G01N2333/96433 ,  G01N2333/96477

Abstract: A method is provided for evaluating the suitability of a duodenal fluid sample collected from an animal as a sample for detecting pancreatic fluid-derived components. The method comprises: (a) mixing a duodenal fluid sample with a chymotrypsin-specific substrate and measuring an amount of degradation the chymotrypsin-specific substrate by of the duodenal fluid sample, (b) mixing the duodenal fluid sample with a pepsin-specific substrate and measuring an amount of degradation of the pepsin-specific substrate by the duodenal fluid sample, and (c) evaluating that the duodenal fluid sample is suitable as a sample for detecting pancreatic fluid-derived components if the amount of degradation of the chymotrypsin-specific substrate by the duodenal fluid sample is higher than a prescribed threshold value and the amount of degradation of the pepsin-specific substrate by the duodenal fluid sample is lower than a prescribed threshold value, as being suitable as a sample for detecting pancreatic fluid-derived components.