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公开(公告)号:USD961091S1
公开(公告)日:2022-08-16
申请号:US29715151
申请日:2019-11-27
申请人: NOVOCURE GMBH
设计人: Eilon Kirson , Yoram Wasserman , Noa Halavee
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公开(公告)号:US12011588B2
公开(公告)日:2024-06-18
申请号:US18163165
申请日:2023-02-01
申请人: NOVOCURE GMBH
发明人: Noa Kaynan , Tali Voloshin-Sela , Moshe Giladi , Eilon Kirson
CPC分类号: A61N1/32 , A61M37/00 , A61M2205/054
摘要: Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time. The alternating electric field has a frequency and a field strength such that when the alternating electric field is imposed in the target region for the duration of time, the alternating electric field inhibits infection of the cells in the target region by the virus. Optionally, the inhibition of viral infections using the alternating electric field approach can be combined with delivering an antiviral agent to the target region so that a therapeutically effective dose of the antiviral agent is present in the target region while the alternating electric fields are imposed.
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公开(公告)号:US11607543B2
公开(公告)日:2023-03-21
申请号:US17942910
申请日:2022-09-12
申请人: Novocure GmbH
发明人: Yoram Wasserman , Zeev Bomzon , Hadas Sara Hershkovich , Ariel Naveh , Moshe Giladi , Eilon Kirson , Golan Bar-Tal , Tali Voloshin-Sela
摘要: Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.
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公开(公告)号:US11872391B2
公开(公告)日:2024-01-16
申请号:US17545248
申请日:2021-12-08
申请人: Novocure GmbH
发明人: Eilon Kirson , Yoram Wasserman , Noa Halavee
CPC分类号: A61N1/0492 , A61N1/0496 , A61N1/36002 , A61N1/0476
摘要: A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers. The transducer array has features that increase its flexibility and adhesion to the patient's skin, including a branching configuration and a correspondingly branching top covering adhesive-backed layer. Additionally, a skin-level adhesive layer is provided beneath the flex circuit to which the electrode elements are attached, to help ensure thorough, lasting adhesion of the transducer array to the patient's skin over the course of treatment.
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公开(公告)号:US11642514B2
公开(公告)日:2023-05-09
申请号:US17190979
申请日:2021-03-03
申请人: Novocure GmbH
发明人: Yoram Wasserman , Cornelia Wenger , Pedro Michael Cavaleiro Miranda , Zeev Bomzon , Noa Urman , Eilon Kirson , Yoram Palti
IPC分类号: A61B5/05 , A61B5/053 , A61B5/055 , A61B5/24 , A61B5/316 , A61B5/00 , A61N1/40 , G16H50/50 , A61N1/04 , A61N1/36 , G16Z99/00 , A61N1/32
CPC分类号: A61N1/0456 , A61B5/0042 , A61B5/05 , A61B5/053 , A61B5/055 , A61B5/24 , A61B5/316 , A61B5/4064 , A61N1/0476 , A61N1/32 , A61N1/36002 , A61N1/36025 , A61N1/40 , G16H50/50 , G16Z99/00
摘要: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by generating a 3D map of electrical conductivity or resistivity of the anatomic volume. A location of the target tissue within the anatomic volume is identified, and a dipole is added to the 3D map at a location that corresponds to the target tissue. positions for the electrodes that maximize a potential attributable to the dipole are determined based on the 3D map of electrical conductivity or resistivity and the location of the dipole.
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公开(公告)号:US11583675B2
公开(公告)日:2023-02-21
申请号:US16506633
申请日:2019-07-09
申请人: Novocure GmbH
发明人: Noa Kaynan , Tali Voloshin-Sela , Moshe Giladi , Eilon Kirson
摘要: Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time. The alternating electric field has a frequency and a field strength such that when the alternating electric field is imposed in the target region for the duration of time, the alternating electric field inhibits infection of the cells in the target region by the virus. Optionally, the inhibition of viral infections using the alternating electric field approach can be combined with delivering an antiviral agent to the target region so that a therapeutically effective dose of the antiviral agent is present in the target region while the alternating electric fields are imposed.
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公开(公告)号:US11452863B2
公开(公告)日:2022-09-27
申请号:US16560306
申请日:2019-09-04
申请人: Novocure GmbH
摘要: Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region.
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公开(公告)号:USD1010136S1
公开(公告)日:2024-01-02
申请号:US29843600
申请日:2022-06-22
申请人: NOVOCURE GMBH
设计人: Eilon Kirson , Yoram Wasserman , Noa Halavee
摘要: FIG. 1 is a perspective view of an electrode array showing our new design;
FIG. 2 is a top plan view of the electrode array of FIG. 1;
FIG. 3 is a front elevation view of the electrode array of FIG. 1;
FIG. 4 is a rear elevation view of the electrode array of FIG. 1;
FIG. 5 is a left side elevation view of the electrode array of FIG. 1; and,
FIG. 6 is a right side elevation of the electrode array of FIG. 1.
The broken lines, the areas within them, and the unshaded areas bounded by the broken linen and the solid lines depict portions of the electrode array that form no part of the claimed design.-
公开(公告)号:US11857782B2
公开(公告)日:2024-01-02
申请号:US18109539
申请日:2023-02-14
申请人: Novocure GmbH
发明人: Yoram Wasserman , Zeev Bomzon , Hadas Sara Hershkovich , Ariel Naveh , Moshe Giladi , Eilon Kirson , Golan Bar-Tal , Tali Voloshin-Sela
CPC分类号: A61N1/36002 , A61N1/05 , A61N1/3787
摘要: Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.
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公开(公告)号:USD959673S1
公开(公告)日:2022-08-02
申请号:US29715153
申请日:2019-11-27
申请人: NOVOCURE GMBH
设计人: Eilon Kirson , Yoram Wasserman , Noa Halavee
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