Inhibiting viral infection using alternating electric fields

    公开(公告)号:US12011588B2

    公开(公告)日:2024-06-18

    申请号:US18163165

    申请日:2023-02-01

    申请人: NOVOCURE GMBH

    IPC分类号: A61N1/32 A61M37/00

    摘要: Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time. The alternating electric field has a frequency and a field strength such that when the alternating electric field is imposed in the target region for the duration of time, the alternating electric field inhibits infection of the cells in the target region by the virus. Optionally, the inhibition of viral infections using the alternating electric field approach can be combined with delivering an antiviral agent to the target region so that a therapeutically effective dose of the antiviral agent is present in the target region while the alternating electric fields are imposed.

    Inhibiting viral infection using alternating electric fields

    公开(公告)号:US11583675B2

    公开(公告)日:2023-02-21

    申请号:US16506633

    申请日:2019-07-09

    申请人: Novocure GmbH

    IPC分类号: A61N1/32 A61M37/00

    摘要: Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time. The alternating electric field has a frequency and a field strength such that when the alternating electric field is imposed in the target region for the duration of time, the alternating electric field inhibits infection of the cells in the target region by the virus. Optionally, the inhibition of viral infections using the alternating electric field approach can be combined with delivering an antiviral agent to the target region so that a therapeutically effective dose of the antiviral agent is present in the target region while the alternating electric fields are imposed.

    Arrays for longitudinal delivery of TTFields to a body

    公开(公告)号:US11452863B2

    公开(公告)日:2022-09-27

    申请号:US16560306

    申请日:2019-09-04

    申请人: Novocure GmbH

    摘要: Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region.

    Electrode array
    8.
    外观设计

    公开(公告)号:USD1010136S1

    公开(公告)日:2024-01-02

    申请号:US29843600

    申请日:2022-06-22

    申请人: NOVOCURE GMBH

    摘要: FIG. 1 is a perspective view of an electrode array showing our new design;
    FIG. 2 is a top plan view of the electrode array of FIG. 1;
    FIG. 3 is a front elevation view of the electrode array of FIG. 1;
    FIG. 4 is a rear elevation view of the electrode array of FIG. 1;
    FIG. 5 is a left side elevation view of the electrode array of FIG. 1; and,
    FIG. 6 is a right side elevation of the electrode array of FIG. 1.
    The broken lines, the areas within them, and the unshaded areas bounded by the broken linen and the solid lines depict portions of the electrode array that form no part of the claimed design.