公开(公告)号：US20240192202A1

公开(公告)日：2024-06-13

申请号：US18533104

申请日：2023-12-07

Applicant: Nautilus Subsidiary, Inc.

Inventor： Rukshan PERERA ,  Maryam JOUZI ,  Cassandra STAWICKI ,  Torri Elise RINKER ,  Chol YUN ,  Kenneth KUHN ,  Raymond MAK

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54306 ,  G01N33/582

Abstract: Methods of minimizing detection of unintended signals during array-based processes are provided. Methods include the use of sets of fluidic media that inhibit sources of unintended signals during array-based processes. Also provided are systems containing the sets of fluidic media that are configured to perform the array-based processes provided herein.

公开(公告)号：US20240417720A1

公开(公告)日：2024-12-19

申请号：US18744286

申请日：2024-06-14

Applicant: Nautilus Subsidiary, Inc.

Inventor： Michael Augusto DARCY ,  Hongji QIAN ,  Tural AKSEL ,  Sanjib GUHA ,  Chol YUN ,  Ilaria SANDEI ,  Kota KANESHIGE ,  Jonathan LEANO ,  Hugo Iván Arrieta OLIVA ,  Maximilian PRESS

IPC: C12N15/11

Abstract: The present disclosure provides a structured nucleic acid particle comprising a scaffold strand and a plurality of staple strands hybridized to the scaffold, forming a structured nucleic acid particle having a first planar structure coupled to a first protruding structure extending from a face of the first planar structure. Also, the present disclosure provides a structured nucleic acid particle comprising a scaffold strand and a plurality of staple strands hybridized to the scaffold, forming a structured nucleic acid particle having a plurality of planar faces. In some instances, the structured nucleic acid particle has six planar faces.