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公开(公告)号：US11123264B2
公开(公告)日：2021-09-21
申请号：US16313410
申请日：2017-06-27
发明人： Norio Nakatsuji , Hirofumi Suemori , Tsuneo Takahashi , Eihachiro Kawase , Atsushi Taguchi , Ryo Tomii
摘要： A biological sample or drug stored inside a frozen storage container is not susceptible to contamination. The frozen storage container includes a container body with an internal space, and a partition wall which divides the internal space at least into a first space and a second space. In the container body, the first space is liquid-tightly sealed, the second space has an opening which is in communication with the outside, and the second space is liquid-tightly sealable by welding the container body. A frozen storage container system includes the frozen storage container; and a needle member which includes a needle tip portion capable of being inserted into the internal space of the container body and capable of piercing the partition wall, and has a flow path which is opened at the needle tip portion and is opened at a base end portion opposite to the needle tip portion.
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公开(公告)号：US10793822B2
公开(公告)日：2020-10-06
申请号：US15574530
申请日：2016-05-24
IPC分类号： C12M1/00 , C12M1/10 , C12M3/06 , C12M3/00 , B01D63/02 , C12M3/04 , C12M3/02 , B01D63/04 , B01D63/16 , C12M1/36 , B01D61/24
摘要： A means capable of simply and efficiently concentrating a cell suspension. A concentrator has a culture vessel having a first port and a second port, a server bag having a port, a case having a hollow fiber bundle in the internal space, a filtering device having an inlet port, a first outlet port, and a second outlet port, a collection vessel having a port, a liquid supply circuit connected to the first port, the inlet port, and the server bag's port so that flow passages are switchable, a liquid discharge circuit connected to the second port, the first outlet port, the second outlet port, and the collection vessel's port so that flow passages are switchable, a liquid supply mechanism having a switching mechanism, a supply pump, and a discharge pump, and a rotation mechanism rotating the filtering device.
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公开(公告)号：US20180148680A1
公开(公告)日：2018-05-31
申请号：US15574530
申请日：2016-05-24
CPC分类号： C12M47/02 , B01D61/243 , B01D63/02 , B01D63/04 , B01D63/16 , B01D2313/06 , B01D2313/10 , B01D2313/12 , B01D2315/02 , B01D2315/18 , C12M1/10 , C12M3/02 , C12M3/043 , C12M3/06 , C12M3/065 , C12M23/14 , C12M23/42 , C12M23/44 , C12M23/50 , C12M29/04 , C12M29/16 , C12M41/48
摘要： A means capable of simply and efficiently concentrating a cell suspension. A concentrator has a culture vessel having a first port and a second port, a server bag having a port, a case having a hollow fiber bundle in the internal space, a filtering device having an inlet port, a first outlet port, and a second outlet port, a collection vessel having a port, a liquid supply circuit connected to the first port, the inlet port, and the server bag's port so that flow passages are switchable, a liquid discharge circuit connected to the second port, the first outlet port, the second outlet port, and the collection vessel's port so that flow passages are switchable, a liquid supply mechanism having a switching mechanism, a supply pump, and a discharge pump, and a rotation mechanism rotating the filtering device.
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公开(公告)号：USD1017829S1
公开(公告)日：2024-03-12
申请号：US29784860
申请日：2021-05-21
申请人： NIPRO CORPORATION
设计人： Atsushi Taguchi , Naoaki Yasumura , Kouichi Yokota
摘要： FIG. 1 is a perspective view of a cryopreservation container in accordance with Embodiment 1 of the present design;
FIG. 2 is a front view thereof;
FIG. 3 is a top view thereof;
FIG. 4 is a bottom view thereof;
FIG. 5 is a right side view thereof; and,
FIG. 6 is a perspective view of the cryopreservation container in a state of use.
The broken lines in the drawings depict environmental subject matter and form no part of the claimed design.-
公开(公告)号：US10975345B2
公开(公告)日：2021-04-13
申请号：US15574516
申请日：2016-05-24
申请人： Nipro Corporation
IPC分类号： C12M3/04 , C12M1/36 , C12M1/00 , C12M1/10 , B01L3/00 , C12M1/06 , C12M1/38 , C12M3/02 , C12M3/00
摘要： A compact culture device capable of performing large-scale culture in an aseptic state. A culture device has a culture bag which has ports through which a liquid flows and enables cell culture, a bag holding portion having holding plates holding the culture bag and rotating shafts, a rotation mechanism supporting and rotating the rotating shaft, a liquid supply/discharge mechanism supplying and discharging a liquid to/from the culture bag, and a rotation control portion controlling the rotation of the rotation mechanism. The rotation control portion brings the bag holding portion into a first position in parallel with the approximately horizontal direction according to a first information, brings the bag holding portion into a second position when a culture medium in the culture bag is caused to flow out of the port according to a second information, and brings the bag holding portion into a third position in parallel with the approximately vertical direction at least when a cell suspension in the culture bag is caused to flow out of the port according to a third information.
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公开(公告)号：US10883078B2
公开(公告)日：2021-01-05
申请号：US15574546
申请日：2016-05-24
申请人： Nipro Corporation
摘要： A culture device supplying an accurate amount of liquid into a culture bag has a culture bag having ports, a first bag holding portion having supporting surfaces supporting the culture bag, a rotation mechanism rotating the first bag holding portion, a liquid supplying mechanism supplying a liquid through a tube communicating with the ports a weight detector detecting the weight of the culture bag and the first bag holding portion, and a control portion, in which the control portion sets a first reference value according to a first detection information output from the weight detector in a first state and carries out a liquid supplying step of stopping the liquid supplying mechanism under the condition where a second detection information output from the weight detector when a liquid is supplied to the culturing bag reaches a first target value obtained by adding the weight of the liquid to be supplied to the first reference value.
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