公开(公告)号：US20230040479A1

公开(公告)日：2023-02-09

申请号：US17788010

申请日：2020-07-14

Applicant: NANTONG UNIVERSITY

Inventor： Xiaosong GU ,  Chunkang TANG ,  Leilei GONG ,  Yu ZHANG ,  Qiong CHENG ,  Xiaoming YANG ,  Xiaomin WANG

IPC: A61K36/634 ,  A61K36/481 ,  A61K31/235 ,  A61K9/16 ,  A61P31/16

Abstract: A Fructus Forsythiae and Radix Astragali compound preparation, and a preparation method therefor and a use thereof is provided. Traditional Chinese medicine formulation components consist of the following raw materials or raw material extracts in parts by mass: 9-11 parts of Flos Lonicerae, 9-11 parts of Fructus Forsythiae, 9-11 parts of Radix Scutellariae, 9-11 parts of Herba Artemisiae Annuae, 9-11 parts of Radix Astragali, 9-11 parts of stir-fried Rhizoma Atractylodis Macrocephalae, 9-11 parts of Herba Pogostemonis, 5-7 parts of Radix Saposhnikoviae, 9-11 parts of Radix Ophiopogonis, and 5-7 parts of Radix Glycyrrhizae. The components can be made into an oral liquid, a granule, a dissolved medicine, or a tablet. Further disclosed is a use of the Fructus Forsythiae and Radix Astragali compound preparation in preparation of medicines for preventing and/or treating a viral influenza disease.

公开(公告)号：US20230043437A1

公开(公告)日：2023-02-09

申请号：US17790646

申请日：2021-01-05

Applicant: NANTONG UNIVERSITY

Inventor： Xiaosong GU ,  Chunkang TANG ,  Fei DING ,  Xiaoming YANG ,  Qiong CHENG ,  Hualin SUN ,  Lai XU

IPC: A61K36/481 ,  A61K36/64 ,  A61K36/21 ,  A61K36/725 ,  A61K36/815 ,  A61K36/232 ,  A61K36/286 ,  A61K36/076 ,  A61K36/284

Abstract: Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.

公开(公告)号：US20230210936A1

公开(公告)日：2023-07-06

申请号：US17996076

申请日：2020-08-05

Applicant: NANTONG UNIVERSITY

Inventor： Xiaosong GU ,  Chunkang TANG ,  Leilei GONG ,  Xiaomin WANG ,  Xin TANG

IPC: A61K36/8988 ,  A61K36/74 ,  A61K36/515 ,  A61K36/481 ,  A61K36/64 ,  A61K36/36 ,  A61K36/815 ,  A61K36/232 ,  A61K36/284 ,  A61K36/725 ,  A61K36/52 ,  A61K36/286 ,  A61K35/583 ,  A61P25/16

CPC classification number: A61K36/8988 ,  A61K36/74 ,  A61K36/515 ,  A61K36/481 ,  A61K36/64 ,  A61K36/36 ,  A61K36/815 ,  A61K36/232 ,  A61K36/284 ,  A61K36/725 ,  A61K36/52 ,  A61K36/286 ,  A61K35/583 ,  A61P25/16 ,  A61K2236/331 ,  A61K2236/37 ,  A61K2236/51

Abstract: A traditional Chinese medicine compound preparation for treating Parkinson's disease and its preparation method and application are disclosed. The traditional Chinese medicine compound preparation comprises traditional Chinese medicine formula components and the traditional Chinese medicine formula components comprise the following raw material or raw material extracts by mass: 6-15 parts of uncaria rhynchophylla, 3-9 parts of gastrodia elata, 6-12 parts of Gentiana macrophylla, 10-20 parts of raw astragalus membranaceus, 10-20 parts of prepared rehmannia roots, 10-20 parts of achyranthes roots, 10-20 parts of wolfberry fruits, 10-20 parts of angelica sinensis, 10-20 parts of fried atractylodes macrocephala, 6-15 parts of fried spina date seeds, 3-12 parts of walnut kernels, 3-9 parts of safflower, and 20-30 parts of zaocys dhumnade.

公开(公告)号：US20220213437A1

公开(公告)日：2022-07-07

申请号：US17596647

申请日：2020-06-19

Applicant: NANTONG UNIVERSITY

Inventor： Xin TANG ,  Cheng SUN ,  Xiaosong GU ,  Youlang ZHOU ,  Chunkang TANG

IPC: C12N5/0793 ,  A61L27/26 ,  B82Y5/00 ,  C07K14/78

Abstract: A protein-modified PLGA microsphere can be used to construct tissue-engineered nerve. The microspheres are loaded with active substances for treating peripheral nerve injury and are bound to tissue-engineered nerves. It has been shown that the prepared tissue-engineered nerve effectively promotes nerve regeneration after peripheral nerve injury.