摘要:
A production process for a microneedle arrangement and a corresponding microneedle arrangement as well as a use for it is disclosed. The process has the following steps: forming an etching mask in grid form, with grid bars with corresponding grid crossing regions and grid openings in between on a substrate; carrying out an etching process to form the microneedle arrangement on the substrate using the etching mask and removing the etching mask. The etching mask in grid form has at least some of the grid crossing regions flat reinforcing regions, which extend beyond the grid bars.
摘要:
A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, a flat electrode in which the interdigital electrode system and the flat electrode are situated on opposite sides of the cell in order to improve the separation, accumulation and/or lysis characteristics. Moreover, a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles is also described.
摘要:
The invention relates to an economical pressure measuring device as well as to a favorable method for pressure determination, with which a pressure measurement can be performed from outside the high-pressure container. To that end, the device comprises an ultrasound transmitter mounted outside the pressure container and an ultrasound receiver by means of which transmitter and receiver the transit time of an ultrasonic pulse traveling through the liquid contained in the high-pressure container can be ascertained, and the method comprises generating an ultrasonic pulse outside the high-pressure container measuring the time that the ultrasonic pulse requires to traverse a defined distance calculating the pulse speed of the pulse in the liquid; and from that determining the pressure in the liquid.
摘要:
A method for active hybridization in microarrays includes pumping an already prepared sample through a denaturing unit with a microarray and then through a reaction region which is spatially separate from the denaturing unit. The denatured reactive sample components are hybridized in the reaction region.
摘要:
A manufacturing method for a porous microneedle array includes: forming a plurality of porous microneedle arrays, each having at least one microneedle and a porous carrier zone lying beneath it on the face of a semiconductor substrate; forming an interlayer between a non-porous residual layer of the semiconductor substrate located on the back side of the semiconductor substrate and the carrier zone, which has greater porosity than the carrier zone; detaching the residual layer from the carrier zone by breaking up the interlayer; and separating the microneedle arrays into corresponding chips.
摘要:
A medication dosing device for administering a liquid medication, having a housing, the housing having a medication reservoir, a medication dosing unit, a drive for conveying the medication, an administration needle, a power supply unit, and an electrical control system. The medication reservoir, the medication dosing unit, and the administration needle are jointly situated in a unit which may be inserted .into the housing and removed from the housing. The medication dosing device has the advantage that it may be easily manufactured and cost-effectively operated.
摘要:
A manufacturing method for a porous microneedle array includes: forming a plurality of porous microneedle arrays, each having at least one microneedle and a porous carrier zone lying beneath it on the face of a semiconductor substrate; forming an interlayer between a non-porous residual layer of the semiconductor substrate located on the back side of the semiconductor substrate and the carrier zone, which has greater porosity than the carrier zone; detaching the residual layer from the carrier zone by breaking up the interlayer; and separating the microneedle arrays into corresponding chips.
摘要:
A method for producing porous microneedles (10) situated in an array on a silicon substrate includes: providing a silicon substrate, applying a first etching mask, patterning microneedles using a DRIE process (“deep reactive ion etching”), removing the first etching mask, at least partially porosifying the Si substrate, the porosification beginning on the front side of the Si substrate and a porous reservoir being formed.
摘要:
An integrated microstructure sensor element is proposed for detecting thermodynamic measured variables of a fluid. To that end, a supporting body, particularly a board or a wafer having at least one microstructured heating element in contact with the fluid during operation, is provided, on which or in whose vicinity are arranged first arrangement for at least intermittently acting on the heating element with an electric alternating current of defined frequency or a defined frequency band, as well a second arrangement for detecting the amplitude of the third harmonic wave of the electric voltage applied to the heating element. The proposed microstructure sensor element in the form of a compact, integrated component is suitable in particular for determining or monitoring the thermal conductivity and/or the thermal capacity of a fluid, particularly an oil in a motor vehicle.
摘要:
A biochip for electrical, e.g., capacitive, detection of biochemical molecules has an electrode array on a substrate, the electrodes of the electrode array being each connected through the substrate to an electrically conductive contact surface via an electrical conductor. The contact surfaces are situated on the side of the substrate facing away from the electrode array and form the outermost plane of the substrate on this side.