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    Method and apparatus for minimally invasive treatment of chronic venous insufficiency
    1.
    发明授权
    Method and apparatus for minimally invasive treatment of chronic venous insufficiency 失效
    用于微创治疗慢性静脉功能不全的方法和装置

    公开(公告)号：US5810847A

    公开(公告)日：1998-09-22

    申请号：US812758

    申请日：1997-03-06

    申请人： Michael D. Laufer ,  H. DuBose Montgomery

    发明人： Michael D. Laufer ,  H. DuBose Montgomery

    IPC分类号： A61F2/06 ,  A61B17/122 ,  A61F2/24 ,  A61B17/10

    CPC分类号： A61F2/2475 ,  A61B17/122

    摘要： The invention is embodied in an appliance or a prosthesis and a delivery catheter for use in a vein for minimally invasive treatment of chronic venous insufficiency. The system and method of the invention eliminate the need for open surgical valve repair procedures, obviate the need for arm vein transplantation into the leg, and allow patients to return to their former active lifestyles without the limitations currently associated with the treatment of this condition. An incompetent valve to be repaired is identified by injected contrast through the delivery catheter or similar means and the catheter is positioned at that valve, a clip appliance or similar prosthesis is deployed from the catheter and affixed to the valve. Next, the delivery catheter is repositioned and appliances or prostheses are deployed on sequentially lower valves until all desired valves are repaired and functionally competent.

    摘要翻译： 本发明体现在用于静脉中用于慢性静脉功能不全的微创治疗的器具或假体和输送导管中。 本发明的系统和方法消除了对开放式手术瓣膜修复程序的需要，从而避免了将臂静脉移植到腿部中的需要，并且允许患者返回到其以前的活跃生活方式，而没有目前与该病症的治疗相关的限制。 通过输送导管或类似装置的注射对比来识别待修复的无能的瓣膜，并且导管定位在该阀处，夹具装置或类似的假体从导管部署并固定到瓣膜上。 接下来，输送导管被重新定位，并且将器具或假体部署在顺序下降的阀上，直到所有期望的阀被修复和功能上胜任。

    Method and apparatus for minimally invasive treatment of chronic venous insufficiency
    2.
    发明授权
    Method and apparatus for minimally invasive treatment of chronic venous insufficiency 失效
    用于微创治疗慢性静脉功能不全的方法和装置

    公开(公告)号：US5609598A

    公开(公告)日：1997-03-11

    申请号：US367063

    申请日：1994-12-30

    申请人： Michael D. Laufer ,  H. DuBose Montgomery

    发明人： Michael D. Laufer ,  H. DuBose Montgomery

    IPC分类号： A61F2/06 ,  A61B17/122 ,  A61F2/24 ,  A61B17/10

    CPC分类号： A61F2/2475 ,  A61B17/122

    摘要： The invention is embodied in an appliance or a prosthesis and a delivery catheter for use in a vein for minimally invasive treatment of chronic venous insufficiency. The system and method of the invention eliminate the need for open surgical valve repair procedures, obviate the need for arm vein transplantation into the leg, and allow patients to return to their former active lifestyles without the limitations currently associated with the treatment of this condition. An incompetent valve to be repaired is identified by injected contrast through the delivery catheter or similar means and the catheter is positioned at that valve, a clip appliance or similar prosthesis is deployed from the catheter and affixed to the valve. Next, the delivery catheter is repositioned and appliances or prostheses are deployed on sequentially lower valves until all desired valves are repaired and functionally competent.

    摘要翻译： 本发明体现在用于静脉中用于慢性静脉功能不全的微创治疗的器具或假体和输送导管中。 本发明的系统和方法消除了对开放式手术瓣膜修复程序的需要，从而避免了将臂静脉移植到腿部中的需要，并且允许患者返回到其以前的活跃生活方式，而没有目前与该病症的治疗相关的限制。 通过输送导管或类似装置的注射对比来识别待修复的无能的瓣膜，并且导管定位在该阀处，夹具装置或类似的假体从导管部署并固定到瓣膜上。 接下来，输送导管被重新定位，并且将器具或假体部署在顺序下降的阀上，直到所有期望的阀被修复和功能上胜任。

    Methods and devices for diastolic assist
    3.
    发明授权
    Methods and devices for diastolic assist 有权

    公开(公告)号：US10987164B2

    公开(公告)日：2021-04-27

    申请号：US16185402

    申请日：2018-11-09

    申请人： Michael D. Laufer ,  Freddy Abnousi

    发明人： Michael D. Laufer ,  Freddy Abnousi

    IPC分类号： A61B18/14 ,  A61M1/10 ,  A61M1/12 ,  A61B17/3209 ,  A61B18/20 ,  A61B17/00 ,  A61B17/32 ,  A61B17/30 ,  A61B18/00

    摘要： The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. For example, improving a diastolic heart function in a heart by creating at least one incision in cardiac muscle forming an interior heart wall of the interior chamber where the at least one incision extends into one or more layers of the interior heart wall without puncturing through the interior heart wall and the incision is sufficient to reduce a stiffness of the interior chamber to increase volume of the chamber and reduce diastolic filling pressure.

    Methods and devices for diastolic assist
    4.
    发明授权
    Methods and devices for diastolic assist 有权

    公开(公告)号：US10154879B2

    公开(公告)日：2018-12-18

    申请号：US15719347

    申请日：2017-09-28

    申请人： Michael D. Laufer ,  Freddy Abnousi

    发明人： Michael D. Laufer ,  Freddy Abnousi

    IPC分类号： A61N1/362 ,  A61B18/14 ,  A61M1/10 ,  A61B17/3209 ,  A61M1/12 ,  A61B18/20 ,  A61B17/00 ,  A61B17/32 ,  A61B17/30 ,  A61B18/00

    摘要： The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. For example, improving a diastolic heart function in a heart by creating at least one incision in cardiac muscle forming an interior heart wall of the interior chamber where the at least one incision extends into one or more layers of the interior heart wall without puncturing through the interior heart wall and the incision is sufficient to reduce a stiffness of the interior chamber to increase volume of the chamber and reduce diastolic filing pressure.

    Device for tissue injection
    6.
    发明授权
    Device for tissue injection 有权
    组织注射装置

    公开(公告)号：US08870821B2

    公开(公告)日：2014-10-28

    申请号：US11549454

    申请日：2006-10-13

    申请人： Michael D. Laufer

    发明人： Michael D. Laufer

    IPC分类号： A61M37/00

    CPC分类号： A61M37/00

    摘要： A system for administering an injection is described. The invention consists of an adhesive patch with an integrated injector that controllably insets an injection needle and delivers the medication contained within the patch. Variations of the system may also subsequently and automatically retracts the needle, rendering the patch safely inert. In additional variations, a portion of the system may remain on the patient and function as a bandage.

    摘要翻译： 描述了用于施用注射的系统。 本发明包括具有集成注射器的粘合贴片，其可控制地插入注射针并递送包含在贴片内的药物。 系统的变化也可以随后并且自动缩回针，使贴片安全地惰性。 在另外的变型中，系统的一部分可以保留在患者身上并用作绷带。

    Location and deactivation of muscles
    7.
    发明授权
    Location and deactivation of muscles 失效
    肌肉的位置和停用

    公开(公告)号：US08521295B2

    公开(公告)日：2013-08-27

    申请号：US11743121

    申请日：2007-05-01

    申请人： Michael D. Laufer

    发明人： Michael D. Laufer

    IPC分类号： A61N1/18

    CPC分类号： A61B5/04001 ,  A61B5/4041 ,  A61B5/4893 ,  A61B18/14 ,  A61B2018/00434 ,  A61N1/0551 ,  A61N1/328 ,  A61N7/02

    摘要： Methods and devices for treatment to at least interfere with the function of a muscle are described herein. These methods and devices may have application in cosmetic and plastic surgery, dermatology, suppression of tension and/or migraine-type headaches, pain management, one particular application of the subject matter deals primarily with reducing wrinkles caused by ongoing muscular activation. The devices and methods described herein allow medical practitioners to effectively identify selective nerves for paralyzingmuscles, without the need for injections of agents such as botulism toxin. Moreover, the devices and methods herein, may allow for artificial generation of signals in nerves that were otherwise damaged by stimulating transmission of nerve signals across damaged nerves.

    摘要翻译： 本文描述了至少干扰肌肉功能的治疗方法和装置。 这些方法和装置可以应用于化妆和整形手术，皮肤病学，抑制紧张和/或偏头痛型头痛，疼痛管理，主题的一个特定应用主要涉及减少正在进行的肌肉活化引起的皱纹。 本文描述的装置和方法允许医疗人员有效地识别麻痹肌肉的选择性神经，而不需要注射诸如肉毒杆菌毒素的药剂。 此外，这里的装置和方法可以允许神经中的信号的人工产生，否则通过刺激神经信号穿过受损神经的传播而被损坏。

    Apparatus for Treating Venous Insufficiency Using Directionally Applied Energy
    10.
    发明申请
    Apparatus for Treating Venous Insufficiency Using Directionally Applied Energy 有权
    使用定向应用能量治疗静脉功能不全的装置

    公开(公告)号：US20110202047A1

    公开(公告)日：2011-08-18

    申请号：US13095335

    申请日：2011-04-27

    申请人： Brian E. Farley ,  Michael D. Laufer ,  Dawn A. Henderson ,  Douglas M. Petty ,  Mark K. Parker

    发明人： Brian E. Farley ,  Michael D. Laufer ,  Dawn A. Henderson ,  Douglas M. Petty ,  Mark K. Parker

    IPC分类号： A61B18/22

    CPC分类号： A61B18/1492 ,  A61B17/00008 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/1253 ,  A61B2018/126

    摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.

    摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加，以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并且具有功能上的能力。