公开(公告)号：US20240359180A1

公开(公告)日：2024-10-31

申请号：US18541650

申请日：2023-12-15

Applicant: Mammoth Biosciences, Inc.

Inventor： Timothy James PATNO ,  Phillip You Fai LEE ,  Benjamin Andrew BLIZARD ,  Xin MIAO ,  Jacob LESINSKI ,  Ryan A. BROWN ,  Daniel Thomas DRZAL ,  Sarah Jane SHAPIRO ,  Joshua BAIK ,  Janice Sha CHEN ,  James Paul BROUGHTON ,  Clare Louise FASCHING ,  Jesus CHING ,  Sonal JAIN ,  Deepika VERMA ,  Matthew VEROSLOFF ,  Devin SPRATT ,  Nicholas John FANTIN

IPC: B01L3/00

CPC classification number: B01L3/502761 ,  B01L2200/0647 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0663 ,  B01L2300/161 ,  B01L2300/1805 ,  B01L2400/06

Abstract: The present disclosure provides various systems, diagnostic devices, and methods for nucleic acid analysis. The systems, devices, and methods allow for the analysis of nucleic acids, in a sample, via programmable nuclease-based assays. Provided are systems comprising an instrument and a cartridge allowing for point of care use. The systems, devices, and methods described herein can be configured for multiplexed detection of nucleic acids in a single sample.