公开(公告)号：US20240285932A1

公开(公告)日：2024-08-29

申请号：US18652962

申请日：2024-05-02

申请人： Magenta Medical Ltd

发明人： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC分类号： A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

摘要： Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. The distal end of the axial shaft is configured to engage with a distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. An impeller-stabilizing spring is disposed around the axial shaft between a distal end of the impeller and the thrust bearing, the impeller-stabilizing spring being configured to stabilize the distal end of the impeller. Other applications are also described.

公开(公告)号：US20240189571A1

公开(公告)日：2024-06-13

申请号：US18444972

申请日：2024-02-19

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including a blood pump that includes an impeller configured to be delivered through vasculature of a subject while the impeller is in a radially-constrained configuration. The impeller is configured to self-expand to a non-radially-constrained configuration, and to pump blood while in the non-radially-constrained configuration. A ratio between (a) a diameter of the impeller when the impeller is in its non-radially-constrained configuration at a location at which the diameter of the impeller is at its maximum and (b) a diameter of the impeller when the impeller is in its radially-constrained configuration is greater than 7:2. Other applications are also described.

公开(公告)号：US11883274B2

公开(公告)日：2024-01-30

申请号：US16677893

申请日：2019-11-08

申请人： Magenta Medical Ltd.

发明人： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC分类号： A61M1/12 ,  A61F2/07 ,  A61M60/135 ,  A61M60/422 ,  A61M60/833 ,  A61M60/411 ,  A61M60/861 ,  A61M60/523 ,  A61M60/237 ,  A61M60/808 ,  A61M60/825 ,  A61M60/13 ,  A61M60/81 ,  A61M60/33 ,  A61B5/0205 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896

CPC分类号： A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

摘要： Apparatus and methods are described for improving renal function of a patient, including mechanically occluding the patient's inferior vena cava downstream of the renal vein ostium to form an upstream region and a downstream region of the inferior vena cava, and mechanically pumping blood through the inferior vena cava from the upstream region to a discharge location in the downstream region while the inferior vena cava is occluded, wherein the blood remains in the inferior vena cava while being mechanically pumped. Other applications are also described.

公开(公告)号：US11844592B2

公开(公告)日：2023-12-19

申请号：US17077769

申请日：2020-10-22

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC分类号： A61B5/0215 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61M60/135 ,  A61M60/148 ,  A61M60/857 ,  F04D3/02 ,  A61M60/422 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/896 ,  A61M60/237 ,  A61M60/531 ,  A61M60/554

CPC分类号： A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

摘要： Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.

公开(公告)号：US20230233841A1

公开(公告)日：2023-07-27

申请号：US18130698

申请日：2023-04-04

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC分类号： A61M60/833 ,  A61M60/416 ,  A61M60/13 ,  A61M60/216 ,  A61M60/804 ,  A61M60/818 ,  A61M60/585 ,  A61M60/531 ,  A61M60/139

CPC分类号： A61M60/833 ,  A61M60/416 ,  A61M60/13 ,  A61M60/216 ,  A61M60/804 ,  A61M60/818 ,  A61M60/585 ,  A61M60/531 ,  A61M60/139 ,  A61M60/414

摘要： Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A first impeller cage is disposed around the first impeller, and a second impeller cage is disposed around the second impeller. A sleeve extends longitudinally along more than 50 percent of a distance between the first and second impellers. Other applications are also described.

公开(公告)号：US11684275B2

公开(公告)日：2023-06-27

申请号：US17069064

申请日：2020-10-13

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC分类号： A61B5/0215 ,  F04D15/00 ,  F04D29/042 ,  F04D29/18 ,  F04D7/00 ,  A61M60/135 ,  A61M60/148 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/237 ,  F04D3/02 ,  F04D29/041 ,  F04D25/02 ,  F04D29/24 ,  A61B5/283 ,  A61M60/422 ,  A61M60/896 ,  A61M60/531 ,  A61M60/554

CPC分类号： A61B5/0215 ,  A61B5/283 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

摘要： Apparatus comprising and methods are described including a blood pump that includes an axial shaft, and an impeller disposed on the axial shaft. The impeller is configured to pump blood of the subject by rotating. The impeller and the axial shaft are configured to undergo axial back-and-forth motion during operation of the impeller. A distal tip element is disposed at a distal end of the blood pump. The distal tip element defines an axial-shaft-receiving tube, configured to receive at least a portion of the axial shaft during forward motion of the axial shaft. The distal tip element additionally defines an atraumatic distal tip portion disposed distally of the axial-shaft-receiving tube. Other applications are also described.

公开(公告)号：US11666747B2

公开(公告)日：2023-06-06

申请号：US16810116

申请日：2020-03-05

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216 ,  A61M60/237 ,  A61M60/825 ,  A61M60/531 ,  A61M60/13 ,  A61M60/894 ,  A61M60/135 ,  A61M60/818 ,  A61M60/122 ,  A61M60/205

CPC分类号： A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

摘要： Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends that are connected to one another by at least one elongate element. The elongate element is made to radially expand and form a helical elongate element. An elastomeric material is coupled to the helical elongate element, such that the helical elongate element with the elastomeric material coupled thereto defines a blade of the impeller. The coupling is performed such that a layer of the material disposed around a radially outer edge of the helical elongate element forms the effective edge of the impeller blade. A step is performed to enhance bonding of the elastomeric material to the helical elongate element in a manner that does not cause a protrusion from the effective edge of the impeller blade. Other applications are also described.

公开(公告)号：US11484701B2

公开(公告)日：2022-11-01

申请号：US15888771

申请日：2018-02-05

申请人： MAGENTA MEDICAL LTD.

发明人： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC分类号： A61M60/833 ,  A61M60/135 ,  A61M60/857 ,  A61B17/12 ,  A61M60/205 ,  A61M60/422

摘要： Apparatus and methods are described including a catheter, a first pump disposed on the catheter, and a second pump disposed on the catheter, proximally to the first pump. A control unit is configured to control activation of the first and second pumps. The first and second pumps are configured, when activated, to pump fluid in opposite directions from one another. Other applications are also described.

公开(公告)号：US20220241575A1

公开(公告)日：2022-08-04

申请号：US17723150

申请日：2022-04-18

申请人： Magenta Medical Ltd.

发明人： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC分类号： A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216

摘要： Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta such as to cause the proximal portion of the tube to be maintained in an open state, and to cause at least a portion of the tube to become curved. Other applications are also described.

公开(公告)号：US20220218976A1

公开(公告)日：2022-07-14

申请号：US17608312

申请日：2020-05-20

申请人： MAGENTA MEDICAL LTD

发明人： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC分类号： A61M60/13 ,  A61M60/216 ,  A61B17/12 ,  A61M60/857 ,  A61M60/531 ,  A61M60/546

摘要： Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.