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    Device For Measuring The Conductivity Of A Liquid In Order To Determine Very Low Levels Of Total Organic Carbon (TOC) In Pure And Ultra-Pure Water
    1.
    发明申请
    Device For Measuring The Conductivity Of A Liquid In Order To Determine Very Low Levels Of Total Organic Carbon (TOC) In Pure And Ultra-Pure Water 审中-公开
    用于测量液体电导率的装置，以确定纯超纯水中总有机碳（TOC）的极低水平

    公开(公告)号：US20160084784A1

    公开(公告)日：2016-03-24

    申请号：US14889590

    申请日：2014-04-14

    Applicant: MERCK PATENT GMBH

    Inventor： Pascal Rajagopalan ,  Yves Gaignet ,  Celine Le Ninivin Glipa

    IPC: G01N27/06 ,  G01N33/18

    Abstract: The present patent application relates to a device (1) for measuring the conductivity of a liquid, which comprises a measuring chamber for containing a sampling volume to be irradiated with UV rays formed in a hydraulic body (4) which comprises an inlet channel for feeding the measuring chamber with liquid to be measured and an outlet channel for removing the measured liquid from the measuring chamber, the inlet channel and the outlet channel emerging on either side beyond a surface exposed to the UV rays, such that only the sampling volume contained in the measuring chamber is irradiated. The present patent application is also directed towards a use of such a device and to a purification system comprising such a device.

    Abstract translation: 本专利申请涉及一种用于测量液体的导电性的装置（1），其包括用于容纳要在液压体（4）中形成的紫外线照射的取样体积的测量室，该液体体包括用于进料的入口通道 具有待测量液体的测量室和用于从测量室移除测量液体的出口通道，入口通道和出口通道出现在暴露于紫外线的表面之外的两侧，使得仅包含在 照射测量室。 本专利申请还涉及使用这种装置和包括这种装置的净化系统。

    Flow-Through Fluid Purification Device And Means For Accommodating A Radiation Source
    2.
    发明申请
    Flow-Through Fluid Purification Device And Means For Accommodating A Radiation Source 审中-公开

    公开(公告)号：US20200062615A1

    公开(公告)日：2020-02-27

    申请号：US16485830

    申请日：2017-02-20

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano

    IPC: C02F1/32 ,  A61L2/10

    Abstract: A flow-through fluid purification device (1), which comprises a container (5) arranged such that fluid to be purified can flow-through a volume (8) of the container (5) from an inlet (3) to an outlet (7), a receptacle (10) for accommodating a radiation source in the form of a lamp (13), wherein the receptacle (10) has an interface wall (11) permeable for radiation with a wavelength in the UV-range, preferably between 150 nm and 200 nm, more preferably of 172±8 nm, and arranged to let radiation pass into the volume (8) of the container (5), a plurality of baffle plates (9) located in the volume (8) of the container (5) with an inter-baffle distance (D) in the flow direction from the inlet (3) to the outlet (7), wherein the baffle plates (9) are arranged to force the fluid flowing from the inlet (3) to the outlet (7) to flow substantially along the interface wall (11) and through gaps (G) between the interface wall (11) and the baffle plates (9) defining the shortest distance between the interface wall (11) and the baffle plates (9), and wherein the baffle plates (9) each have a surface on the upstream side in the flow direction which is perpendicular to the interface wall (11).

    Device And Method For Measuring The Total Organic Carbon Content Of A Sample Fluid
    3.
    发明申请
    Device And Method For Measuring The Total Organic Carbon Content Of A Sample Fluid 审中-公开

    公开(公告)号：US20200003747A1

    公开(公告)日：2020-01-02

    申请号：US16485828

    申请日：2018-02-20

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Pierre Caruso

    IPC: G01N33/18 ,  G01N25/00 ,  G01N27/06 ,  G01N27/04 ,  B01L3/00

    Abstract: A device for measuring the total organic carbon content (TOC) of a sample fluid comprises a measuring cell (2) defining a volume (3) for containing a sample fluid and an excimer lamp (20) arranged to cause an oxidation reaction of the sample fluid by emitting radiation onto the sample fluid in the volume (3). A pair of electrodes is arranged to measure the conductivity of the sample fluid during the oxidation reaction and at least one temperature senor (31) is arranged on the measuring cell (2) to measure a temperature that is related to the sample fluid. The total organic carbon content (TOC) of the sample fluid is determined on the basis of the measured conductivity compensated by the temperature related to the sample fluid.

    Biocidal Purification Device
    5.
    发明申请
    Biocidal Purification Device 有权
    杀菌净化装置

    公开(公告)号：US20160107904A1

    公开(公告)日：2016-04-21

    申请号：US14889603

    申请日：2014-04-24

    Applicant: MERCK PATENT GMBH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano ,  Yves Gaignet ,  Julien Bole

    IPC: C02F1/32

    CPC classification number: C02F1/325 ,  C02F2103/026 ,  C02F2201/3221 ,  C02F2201/3222 ,  C02F2201/3228 ,  C02F2201/326 ,  C02F2209/005 ,  C02F2303/04 ,  C02F2307/02

    Abstract: A biocidal fluid purification cap (2) for a fluid container (1), preferably one storing purified water for use in laboratory environments and especially purified water for cell culture and water for molecular biology. The purification cap (2) includes a cap body (3) including an engagement feature (20) for removably attaching the cap body (3) to a mating engagement feature on a spout of the fluid container (1) to hermetically close a spout opening, at least one LED (7a) adapted to emit light in the UV-C range, electronic circuitry (15) for driving the LED(s) (7a), and a power supply for the electronic circuitry (15). The LED(s) (7a) is/are arranged in said cap body (3) so as to be separated from the environment by an UV-transparent window (6) provided in the cap body (3) such that light emitted from said LED(s) (7a) enters the opening of the spout when the cap (2) is attached to the spout of the container (1).

    Abstract translation: 一种用于流体容器（1）的杀生物流体净化帽（2），优选地存储用于实验室环境中的纯净水，特别是用于细胞培养的纯化水和用于分子生物学的水。 净化盖（2）包括盖主体（3），其包括用于将盖体（3）可移除地附接到流体容器（1）的喷口上的配合接合特征的接合特征（20），以密封地关闭喷口 ，适于在UV-C范围内发光的至少一个LED（7a），用于驱动LED（7a）的电子电路（15）和用于电子电路（15）的电源。 LED（7a）被布置在所述盖体（3）中，以便通过设置在盖主体（3）中的UV透明窗（6）与环境分离，使得从所述盖体 当帽（2）附接到容器（1）的喷口时，LED（7a）进入喷口的开口。

    Flow-through fluid purification device and means for accommodating a radiation source
    6.
    发明授权
    Flow-through fluid purification device and means for accommodating a radiation source 有权

    公开(公告)号：US11286179B2

    公开(公告)日：2022-03-29

    申请号：US16485830

    申请日：2018-02-20

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano

    IPC: A61L2/10 ,  C02F1/32 ,  C02F103/04

    Abstract: A flow-through fluid purification device (1), which comprises a container (5) arranged such that fluid to be purified can flow-through a volume (8) of the container (5) from an inlet (3) to an outlet (7), a receptacle (10) for accommodating a radiation source in the form of a lamp (13), wherein the receptacle (10) has an interface wall (11) permeable for radiation with a wavelength in the UV-range, preferably between 150 nm and 200 nm, more preferably of 172±8 nm, and arranged to let radiation pass into the volume (8) of the container (5), a plurality of baffle plates (9) located in the volume (8) of the container (5) with an inter-baffle distance (D) in the flow direction from the inlet (3) to the outlet (7), wherein the baffle plates (9) are arranged to force the fluid flowing from the inlet (3) to the outlet (7) to flow substantially along the interface wall (11) and through gaps (G) between the interface wall (11) and the baffle plates (9) defining the shortest distance between the interface wall (11) and the baffle plates (9), and wherein the baffle plates (9) each have a surface on the upstream side in the flow direction which is perpendicular to the interface wall (11).

    Biocidal purification device
    7.
    发明授权
    Biocidal purification device 有权

    公开(公告)号：US09695062B2

    公开(公告)日：2017-07-04

    申请号：US15270529

    申请日：2016-09-20

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano ,  Yves Gaignet ,  Julien Bole

    IPC: C02F1/32 ,  C02F103/02

    CPC classification number: C02F1/325 ,  C02F2103/026 ,  C02F2201/3221 ,  C02F2201/3222 ,  C02F2201/3228 ,  C02F2201/326 ,  C02F2209/005 ,  C02F2303/04 ,  C02F2307/02

    Abstract: A biocidal fluid purification cap (2) for a fluid container (1), preferably one storing purified water for use in laboratory environments and especially purified water for cell culture and water for molecular biology. The purification cap (2) includes a cap body (3) including an engagement feature (20) for removably attaching the cap body (3) to a mating engagement feature on a spout of the fluid container (1) to hermetically close a spout opening, at least one LED (7a) adapted to emit light in the UV-C range, electronic circuitry (15) for driving the LED(s) (7a), and a power supply for the electronic circuitry (15). The LED(s) (7a) is/are arranged in said cap body (3) so as to be separated from the environment by an UV-transparent window (6) provided in the cap body (3) such that light emitted from said LED(s) (7a) enters the opening of the spout when the cap (2) is attached to the spout of the container (1).

    Biocidal Purification Device
    8.
    发明申请
    Biocidal Purification Device 审中-公开
    杀菌净化装置

    公开(公告)号：US20170029292A1

    公开(公告)日：2017-02-02

    申请号：US15270529

    申请日：2016-09-20

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano ,  Yves Gaignet ,  Julien Bole

    IPC: C02F1/32

    CPC classification number: C02F1/325 ,  C02F2103/026 ,  C02F2201/3221 ,  C02F2201/3222 ,  C02F2201/3228 ,  C02F2201/326 ,  C02F2209/005 ,  C02F2303/04 ,  C02F2307/02

    Abstract: A biocidal fluid purification cap (2) for a fluid container (1), preferably one storing purified water for use in laboratory environments and especially purified water for cell culture and water for molecular biology. The purification cap (2) includes a cap body (3) including an engagement feature (20) for removably attaching the cap body (3) to a mating engagement feature on a spout of the fluid container (1) to hermetically close a spout opening, at least one LED (7a) adapted to emit light in the UV-C range, electronic circuitry (15) for driving the LED(s) (7a), and a power supply for the electronic circuitry (15). The LED(s) (7a) is/are arranged in said cap body (3) so as to be separated from the environment by an UV-transparent window (6) provided in the cap body (3) such that light emitted from said LED(s) (7a) enters the opening of the spout when the cap (2) is attached to the spout of the container (1).

    Abstract translation: 一种用于流体容器（1）的杀生物流体净化帽（2），优选地存储用于实验室环境中的纯净水，特别是用于细胞培养的纯化水和用于分子生物学的水。 净化盖（2）包括盖主体（3），其包括用于将盖体（3）可移除地附接到流体容器（1）的喷口上的配合接合特征的接合特征（20），以密封地关闭喷口 ，适于在UV-C范围内发光的至少一个LED（7a），用于驱动LED（7a）的电子电路（15）和用于电子电路（15）的电源。 LED（7a）被布置在所述盖体（3）中，以便通过设置在盖主体（3）中的UV透明窗（6）与环境分离，使得从所述盖体 当帽（2）附接到容器（1）的喷口时，LED（7a）进入喷口的开口。

    Biocidal Purification Reactor
    9.
    发明申请
    Biocidal Purification Reactor 有权
    杀菌净化反应器

    公开(公告)号：US20160083272A1

    公开(公告)日：2016-03-24

    申请号：US14889608

    申请日：2014-04-24

    Applicant: Merck Patent GmbH

    Inventor： Pascal Rajagopalan ,  Julien Gross ,  Ichiro Kano ,  Yves Gaignet

    IPC: C02F1/32

    CPC classification number: C02F1/325 ,  C02F2201/3222 ,  C02F2201/3227 ,  C02F2201/3228 ,  C02F2303/04

    Abstract: A biocidal purification reactor, including a main cylinder tube (1A;1B), at least one end cap (2A,2B,2C) closing at least one axial end opening of the main cylinder tube (1A;1B), at least two ports (3A,3B) communicating with the interior volume (4) of the main cylinder tube (1A;1B) in the vicinity of the respective axial ends of the cylinder tube (1A;1B), and at least one of said end caps (2A) or said main cylinder tube (1B) including a UV-light source (7A;7B).

    Abstract translation: 一种杀生物净化反应器，包括主缸筒（1A; 1B），封闭主缸筒（1A; 1B）的至少一个轴向端部开口的至少一个端盖（2A，2B，2C），至少两个端口 （1A，1B）的轴向端部附近与主缸筒（1A; 1B）的内部容积（4）连通的至少一个所述端盖（3A，3B） 2A）或包括UV光源（7A; 7B）的主缸筒（1B）。

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