公开(公告)号：US20230133106A1

公开(公告)日：2023-05-04

申请号：US17977243

申请日：2022-10-31

申请人： Lumicell, Inc.

发明人： Michael Bush ,  Jorge Ferrer ,  David Benjamin Strasfeld ,  Kate Rielly ,  Zachary Lapointe ,  Sean Madden

IPC分类号： G01N21/93 ,  A61B5/00

摘要： Calibration imaging tips and related methods of use are described. In some embodiments, a calibration imaging tip may be positioned on a distal end portion of an imaging device to place a calibration surface within a predetermined distance of a focal plane of the imaging device. The imaging device may then be calibrated using one or more images of the calibration surface.

公开(公告)号：US20180021090A1

公开(公告)日：2018-01-25

申请号：US15721247

申请日：2017-09-29

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Jorge Ferrer

IPC分类号： A61B18/24 ,  A61B18/22 ,  A61B18/12 ,  A61B18/20 ,  A61B18/02 ,  A61B18/14 ,  A61B18/00 ,  A61B17/00

CPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/12 ,  A61B18/14 ,  A61B18/20 ,  A61B18/22 ,  A61B34/20 ,  A61B90/30 ,  A61B90/361 ,  A61B90/39 ,  A61B2017/00057 ,  A61B2017/0011 ,  A61B2018/00029 ,  A61B2018/00351 ,  A61B2018/00434 ,  A61B2018/00565 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00886 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/20351 ,  A61B2018/2283 ,  A61B2503/40 ,  A61B2562/028 ,  A61B2576/00

摘要： The invention provides systems and method for the removal of diseased cells during surgery

公开(公告)号：US20160310213A1

公开(公告)日：2016-10-27

申请号：US15203104

申请日：2016-07-06

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Jorge Ferrer

IPC分类号： A61B18/22 ,  A61B18/02 ,  A61B18/12

CPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/12 ,  A61B18/14 ,  A61B18/20 ,  A61B18/22 ,  A61B34/20 ,  A61B90/30 ,  A61B90/361 ,  A61B90/39 ,  A61B2017/00057 ,  A61B2017/0011 ,  A61B2018/00029 ,  A61B2018/00351 ,  A61B2018/00434 ,  A61B2018/00565 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00886 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/20351 ,  A61B2018/2283 ,  A61B2503/40 ,  A61B2562/028 ,  A61B2576/00

摘要： The invention provides systems and method for the removal of diseased cells during surgery

摘要翻译： 本发明提供了在手术期间去除患病细胞的系统和方法

公开(公告)号：US20230134454A1

公开(公告)日：2023-05-04

申请号：US17977179

申请日：2022-10-31

申请人： Lumicell, Inc.

发明人： Michael Bush ,  Joseph D'Anello ,  Steven Cappetta ,  Jorge Ferrer ,  David Benjamin Strasfeld ,  Ling Xu ,  Sean Madden

IPC分类号： A61B1/06

摘要： Embodiments related to sterilizable handheld medical imaging devices including a rigid imaging tip, a sealed housing, and/or a sealed cable assembly as well as their methods of use and manufacture are described.

公开(公告)号：US11592396B2

公开(公告)日：2023-02-28

申请号：US16829498

申请日：2020-03-25

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Moungi G. Bawendi ,  Jorge Ferrer

IPC分类号： G01N21/64 ,  A61B5/00 ,  A61K49/00 ,  A61B90/00 ,  G01N33/483

摘要： The present invention provides compositions and methods for imaging tumor resections.

公开(公告)号：US11426075B1

公开(公告)日：2022-08-30

申请号：US15684627

申请日：2017-08-23

申请人： Lumicell, Inc.

发明人： David B. Strasfeld ,  W. David Lee ,  Jorge Ferrer

IPC分类号： A61B5/00 ,  G01N33/483 ,  A61K49/00 ,  G01N21/64 ,  A61B90/00

摘要： Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, the image analysis system collects a surgical site image and indicates on a display one or more locations of the identified cancer cells. In some embodiments, the method for identifying residual cancer cells comprises determining and selecting a portion of the surgical site image responsive to an intensity parameter; modifying the selected portion of the surgical site image to determine one or more groups of residual cancer cells based on size; and identifying at least one of the one or more groups of residual cancer cells from the modified portion of the surgical site image using a local-based threshold.

公开(公告)号：US20190223954A1

公开(公告)日：2019-07-25

申请号：US16368073

申请日：2019-03-28

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Jorge Ferrer

IPC分类号： A61B18/24 ,  A61B90/00 ,  A61B18/20 ,  A61B34/20 ,  A61B18/12 ,  A61B18/02 ,  A61B18/22

摘要： The invention provides systems and method for the removal of diseased cells during surgery

公开(公告)号：US10791937B2

公开(公告)日：2020-10-06

申请号：US14211201

申请日：2014-03-14

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Jorge Ferrer ,  David B. Strasfeld

IPC分类号： A61B5/00 ,  A61B90/00 ,  A61K49/00 ,  A61B10/00 ,  A61B90/30

摘要： Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.

公开(公告)号：US20200205930A1

公开(公告)日：2020-07-02

申请号：US16708486

申请日：2019-12-10

申请人： Lumicell, Inc.

发明人： David B. Strasfeld ,  Jorge Ferrer ,  W. David Lee

IPC分类号： A61B90/00 ,  G06T7/00 ,  G01N21/31 ,  G01N21/64 ,  A61B5/00

摘要： Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, a patient-specific threshold used to detect abnormal cells in a surgical site can be determined. A medical imaging device can be configured to produce a set of images of an anatomy of a patient. An image analysis system, comprising one or more processors, can be configured to receive the set of images, and analyze the set of images to determine a patient-specific threshold to use to detect abnormal tissue of the patient.

公开(公告)号：US10285759B2

公开(公告)日：2019-05-14

申请号：US15721247

申请日：2017-09-29

申请人： Lumicell, Inc.

发明人： W. David Lee ,  Jorge Ferrer

IPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/20 ,  A61B34/20 ,  A61B90/00 ,  A61B18/12 ,  A61B18/22 ,  A61B18/14 ,  A61B18/00 ,  A61B90/30 ,  A61B17/00

摘要： The invention provides systems and method for the removal of diseased cells during surgery.