公开(公告)号：US11046727B2

公开(公告)日：2021-06-29

申请号：US15682103

申请日：2017-08-21

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Tom Xu ,  Christopher Trinh ,  Carole Bornarth ,  Brian Evans ,  Mousumi Rath ,  Kathy Tran

IPC: C07H21/02 ,  C12Q1/6876 ,  C12N15/10 ,  C12Q1/6809 ,  C12Q1/6834

Abstract: Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.

公开(公告)号：US11091801B2

公开(公告)日：2021-08-17

申请号：US15198689

申请日：2016-06-30

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christopher Trinh ,  Tom Xu ,  Yating Shi ,  Ferrier Le ,  Claire Marjoribanks

IPC: C12Q1/686 ,  C12Q1/6848

Abstract: A composition comprising a thermostable DNA polymerase; and a PCR inhibitor blocking agent, wherein the PCR inhibitor blocking agent is present in an amount effective to enhance tolerance of an assembled PCR to a PCR inhibitor.