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公开(公告)号：US20230398223A1
公开(公告)日：2023-12-14
申请号：US18305911
申请日：2023-04-24
发明人： Nello MAINOLFI , Nan JI , Arthur F. KLUGE , Matthew M. WEISS , Yi ZHANG
IPC分类号： A61K47/54 , A61P35/00 , A61K31/444 , A61K31/454 , A61K31/427 , A61K31/4439 , A61K31/496 , A61K31/404 , A61K31/53 , A61K31/472 , A61K31/422 , A61K31/5377 , A61K31/519
CPC分类号： A61K47/545 , A61P35/00 , A61K31/444 , A61K31/454 , A61K31/427 , A61K31/4439 , A61K31/519 , A61K31/404 , A61K31/53 , A61K31/472 , A61K31/422 , A61K31/5377 , A61K31/496
摘要： The present invention provides compounds, compositions thereof, and methods of using the same.
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公开(公告)号：US20220348556A1
公开(公告)日：2022-11-03
申请号：US17258339
申请日：2019-07-03
发明人： Yi ZHANG , Nan JI , Arthur F. KLUGE , Matthew M. WEISS
IPC分类号： C07D401/14 , A61P35/00
摘要： The present invention provides compounds, compositions thereof, and methods of using the same for the targeted degradation of proteins, and the treatment of target protein-mediated disorders.
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公开(公告)号：US20230234950A1
公开(公告)日：2023-07-27
申请号：US18059232
申请日：2022-11-28
发明人： Nello MAINOLFI , Nan JI , Arthur F. KLUGE
IPC分类号： C07D417/04 , C07D211/88 , C07D239/22 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/14 , C07D471/04 , C07D487/04
CPC分类号： C07D417/04 , C07D211/88 , C07D239/22 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/14 , C07D471/04 , C07D487/04
摘要： The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.
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公开(公告)号：US20220306631A1
公开(公告)日：2022-09-29
申请号：US17679496
申请日：2022-02-24
发明人： Nan JI , Arthur F. KLUGE , Matthew M. WEISS , Yi ZHANG
IPC分类号： C07D471/14 , C07D495/04 , C07D471/04 , C07D401/04
摘要： The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.
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