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公开(公告)号：US20220112460A1
公开(公告)日：2022-04-14
申请号：US17443501
申请日：2021-07-27
发明人： Young-Keun KIM , Heemin KANG , Min-Jun KO , Sun-Hong MIN
摘要： The present invention relates to a nanocoil-substrate complex for controlling adhesion and differentiation of stem cells, a manufacturing method thereof, and a method of controlling adhesion and differentiation of stem cells by using the nanocoil-substrate complex, and the method of controlling adhesion and differentiation of stem cells may temporally and reversibly control adhesion and phenotypic differentiation of stem cells in vivo and ex vivo by controlling application/non-application of a magnetic field to the nanocoil-substrate complex.
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2.发明公开公开(公告)号：US20230210992A1
公开(公告)日：2023-07-06
申请号：US17836403
申请日：2022-06-09
发明人： Young-Keun KIM , Heemin KANG , THOMAS MYEONGSEOK KOO , Myeong-Soo KIM , Sung-Gue LEE , Gun-Hyu BAE
IPC分类号： A61K41/00 , C12N13/00 , C12N5/0775 , A61N2/00
CPC分类号： A61K41/00 , C12N13/00 , C12N5/0662 , A61N2/004
摘要： The present invention relates to a nanosatellite-substrate complex capable of regulating stem cell adhesion and differentiation, and a method for preparing the same. Moreover, the present invention relates to a method of regulating stem cell adhesion and differentiation by applying a magnetic field to the nanosatellite-substrate complex.
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公开(公告)号：US20220110880A1
公开(公告)日：2022-04-14
申请号：US17368883
申请日：2021-07-07
发明人： Young-Keun KIM , Heemin KANG , Min-Jun KO , Gunhyu BAE
IPC分类号： A61K9/51 , A61K47/69 , C12N5/0786 , C12N13/00
摘要： The present invention relates to a nanohelix-substrate complex for controlling adhesion and polarization of macrophages, a manufacturing method thereof, and a method of controlling adhesion and polarization of macrophages by using the nanohelix-substrate complex, and the method of controlling adhesion and polarization of macrophages may temporally and reversibly control adhesion and phenotypic polarization of macrophages in vivo and ex vivo by controlling application/non-application of a magnetic field to the nanohelix-substrate complex.
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4.发明公开公开(公告)号：US20240258524A1
公开(公告)日：2024-08-01
申请号：US18408128
申请日：2024-01-09
发明人： Young-Keun KIM , Yong-Mook KANG , Ji-Ung CHO , Bum-Chul PARK , Dae-Bum LEE
IPC分类号： H01M4/60 , H01M4/36 , H01M4/52 , H01M10/054 , H01M4/02
CPC分类号： H01M4/60 , H01M4/366 , H01M4/523 , H01M10/054 , H01M2004/021 , H01M2004/027
摘要： The present disclosure relates to an anode active material for a sodium secondary battery, which has a layered crystal structure and is formed of nanoplatelets containing iron oxide having organic anions, and in which the nanoplatelets are provided in plural numbers and formed in a stacking structure spaced apart at a first interval.
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公开(公告)号：US20230301928A1
公开(公告)日：2023-09-28
申请号：US18203222
申请日：2023-05-30
发明人： Young-Keun KIM , Heemin KANG , Min-Jun KO , Gunhyu BAE
IPC分类号： A61K9/51 , C12N5/0786 , C12N13/00 , A61K47/69 , A61N2/00
CPC分类号： A61K9/5115 , A61K9/5123 , C12N5/0645 , C12N13/00 , A61K47/6929 , A61N2/00 , A61N2/002
摘要： The present invention relates to a nanohelix-substrate complex for controlling adhesion and polarization of macrophages, a manufacturing method thereof, and a method of controlling adhesion and polarization of macrophages by using the nanohelix-substrate complex, and the method of controlling adhesion and polarization of macrophages may temporally and reversibly control adhesion and phenotypic polarization of macrophages in vivo and ex vivo by controlling application/non-application of a magnetic field to the nanohelix-substrate complex.
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6.发明公开公开(公告)号：US20230210996A1
公开(公告)日：2023-07-06
申请号：US17834314
申请日：2022-06-07
发明人： Young-Keun KIM , Heemin KANG , THOMAS MYEONGSEOK KOO , Myeong-Soo KIM , Yuri KIM
CPC分类号： A61K47/52 , A61K47/6929 , B82Y5/00
摘要： According to the present invention, it is possible to provide a nanosatellite-substrate complex capable of regulating macrophage adhesion and polarization. In addition, according to the present invention, it is possible to provide a method for preparing a nanosatellite-substrate complex capable of regulating macrophage adhesion and polarization. In addition, according to the present invention, it is possible to provide a method of regulating macrophage adhesion and polarization using the nanosatellite-substrate complex.
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