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    Process for producing quinolone derivatives
    2.
    发明授权
    Process for producing quinolone derivatives 有权
    制备喹诺酮衍生物的方法

    公开(公告)号：US06187926B1

    公开(公告)日：2001-02-13

    申请号：US09420521

    申请日：1999-10-18

    申请人： Tatsushi Osawa ,  Kazuo Kubo ,  Hideko Murooka ,  Tatsuo Nakajima

    发明人： Tatsushi Osawa ,  Kazuo Kubo ,  Hideko Murooka ,  Tatsuo Nakajima

    IPC分类号： C07D215233

    CPC分类号： C07D215/233

    摘要： The present invention relates to a process for producing a 4-quinolone derivative, comprising allowing an o-aminoacetophenone derivative to react with a formic acid in an aprotic solvent in the presence of a suitable base, and adding a protic solvent to the reaction mixture. This is a simple process for producing 4-quinolone derivatives, applicable to large-scale commercial production.

    摘要翻译： 本发明涉及一种4-喹诺酮衍生物的制备方法，其包括在合适的碱存在下使邻氨基苯乙酮衍生物与非质子溶剂中的甲酸反应，并向反应混合物中加入质子溶剂。 这是生产4-喹诺酮衍生物的简单方法，适用于大规模商业化生产。

    NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE
    3.
    发明申请
    NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE 审中-公开
    含氮的芳香杂环衍生物

    公开(公告)号：US20130225581A1

    公开(公告)日：2013-08-29

    申请号：US13810568

    申请日：2011-07-15

    申请人： Takayuki Furuta ,  Kazuo Kubo ,  Toshiyuki Atsumi ,  Maasa Yamanouchi

    发明人： Takayuki Furuta ,  Kazuo Kubo ,  Toshiyuki Atsumi ,  Maasa Yamanouchi

    IPC分类号： C07D495/04 ,  C07D401/14 ,  C07D413/14 ,  C07D401/12

    CPC分类号： C07D495/04 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/14

    摘要： The present invention provides a nitrogen-containing aromatic heterocyclic derivative represented by formula (I): [wherein W represents CR3 (wherein R3 represents a hydrogen atom or the like) or the like, R4 represents a hydrogen atom or the like, R5 represents a hydrogen atom or the like, R9 represents substituted imidazolyl, R12 and R13 may be the same or different, each represent a hydrogen atom or the like, R22 and R23 may be the same or different, each represent a hydrogen atom or the like, R24 represents a hydrogen atom or the like, Y represents C—R25 (wherein R25 represents a hydrogen atom or the like) or the like] or a pharmaceutically acceptable salt thereof and a FGFR inhibitor comprising, as an active ingredient, the nitrogen-containing aromatic heterocyclic derivative or the pharmaceutically acceptable salt thereof, or the like.

    摘要翻译： 本发明提供式（I）表示的含氮芳香族杂环衍生物：[式中，W表示CR 3（式中，R 3表示氢原子等）等，R 4表示氢原子等，R 5表示 氢原子等，R 9表示取代的咪唑基，R 12和R 13可以相同或不同，各自表示氢原子等，R 22和R 23可以相同或不同，分别表示氢原子等，R 24 表示氢原子等，Y表示C-R25（其中R25表示氢原子等）等或其药学上可接受的盐和FGFR抑制剂，作为活性成分，含氮芳香族 杂环衍生物或其药学上可接受的盐等。

    Optical network system and WDM apparatus
    4.
    发明授权
    Optical network system and WDM apparatus 有权
    光网络系统和WDM设备

    公开(公告)号：US08731398B2

    公开(公告)日：2014-05-20

    申请号：US13421327

    申请日：2012-03-15

    申请人： Yuji Akiyama ,  Kazuo Kubo ,  Sota Yoshida

    发明人： Yuji Akiyama ,  Kazuo Kubo ,  Sota Yoshida

    IPC分类号： H04B10/00

    CPC分类号： H04J3/14 ,  H04J3/1611 ,  H04J2203/006

    摘要： An optical network system that performs transmission of N:1 protection includes a node that includes transmission-side operating muxponders that multiplex client signals for every M-channel signal bundle and convert multiplexed signals into optical signals having different wavelengths, transmission-side optical couplers that branch the client signals into two channels of operating and redundant, transmission-side optical switches each selecting one channel from redundant signals as a redundant client signal, and a transmission-side redundant muxponder that performs a predetermined transmission-side process according to an accommodation mode set on the redundant client signal and then multiplexes the redundant client signals, converts the multiplexed signal into an optical signal having a wavelength different from that of the operating signal, thereby making the accommodation mode settable for each channel in an independent manner.

    摘要翻译： 执行N：1保护的传输的光网络系统包括：节点，其包括传输侧操作的多路复用应答器，其将每个M信道信号束的客户信号复用并将多路复用信号转换成具有不同波长的光信号;传输侧光耦合器， 将客户端信号分为两个通道的操作和冗余的发送侧光交换机，每个从冗余信号中选择一个信道作为冗余客户端信号;以及发送侧冗余复用应答器，其根据调节模式执行预定的发送侧处理 设置在冗余客户端信号上，然后复用冗余客户端信号，将多路复用信号转换成具有与操作信号波长不同的波长的光信号，从而以独立的方式使每个信道的调节模式可设置。

    GAS METER AND GAS SAFETY SYSTEM
    6.
    发明申请
    GAS METER AND GAS SAFETY SYSTEM 有权
    气体表和气体安全系统

    公开(公告)号：US20110004353A1

    公开(公告)日：2011-01-06

    申请号：US12921340

    申请日：2009-02-24

    申请人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

    发明人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

    IPC分类号： G05D7/06

    CPC分类号： G01F15/068 ,  F23N5/242 ,  F23N2025/04 ,  F23N2031/14 ,  G08B21/16 ,  Y10T137/7062

    摘要： Setting safety function, as appropriate, according to a user environment is enabled, thereby enhancing safety function. According to selection information from a safety function selection unit 120, a function setting unit 116 sets arbitrary function among a plurality of functions as safety function pertaining to usage of a gas. When operating conditions for safety function are fulfilled, a monitoring unit 112 detects malfunction, which would arise during usage of a gas, and outputs a safety signal to a control unit 114 in accordance with the set safety function. In accordance with a safety signal from the monitoring unit 112, the control unit 114 cuts off a gas supply when an event fulfilling operating conditions for the set function has arisen. When an event fulfilling operating conditions for an unset function has arisen, a communication unit 124 reports occurrence of malfunction pertaining to unset function to the monitoring center 200.

    摘要翻译： 可根据用户环境设置安全功能，从而提高安全性。 功能设定单元116根据来自安全功能选择单元120的选择信息，将多个功能中的任意功能设置为与气体的使用有关的安全功能。 当满足安全功能的操作条件时，监视单元112检测在使用气体期间将发生的故障，并且根据所设置的安全功能将安全信号输出到控制单元114。 根据来自监视单元112的安全信号，当产生满足设定功能的操作条件的事件时，控制单元114切断气体供应。 当产生满足未设定功能的操作条件的事件时，通信单元124向监视中心200报告与未设置功能相关的故障的发生。

    Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor
    7.
    发明授权
    Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor 失效
    喹啉衍生物和喹唑啉衍生物抑制巨噬细胞集落刺激因子受体的自磷酸化

    公开(公告)号：US07598258B2

    公开(公告)日：2009-10-06

    申请号：US10510961

    申请日：2003-05-01

    申请人： Kazuo Kubo ,  Hiroaki Ohno ,  Toshiyuki Isoe ,  Tuyoshi Nishitoba

    发明人： Kazuo Kubo ,  Hiroaki Ohno ,  Toshiyuki Isoe ,  Tuyoshi Nishitoba

    IPC分类号： C07D215/38 ,  A61K31/44

    CPC分类号： C07D215/233 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/5377 ,  C07D417/12

    摘要： An objective of the present invention is to provide compounds which have inhibitory activity against autophosphorylation of macrophage colony-stimulating factor receptors. The compounds of the present invention are represented by formula (I) and salt and solvate thereof: wherein X represents CH or N; Z represents O or S; R1, R2, and R3 represent H, optionally substituted alkoxy or the like; R4 represents H; R5, R6, R7, and R8 represent H, halogen, alkyl, alkoxy, trifluoromethyl or the like; R9 and R10 represent H, alkyl or the like; and any one of R11 and R12 represents H with the other representing alkyl and R13 represents an optionally substituted carbocyclic or heterocyclic ring or the like, or R11 represents H and R12 and R13 combine together to form a bicyclic carbocyclic ring.

    摘要翻译： 本发明的目的是提供对巨噬细胞集落刺激因子受体的自磷酸化具有抑制活性的化合物。 本发明的化合物由式（I）表示，其盐和溶剂化物：其中X表示CH或N; Z表示O或S; R1，R2和R3表示H，任选取代的烷氧基等; R4表示H; R5，R6，R7和R8表示H，卤素，烷基，烷氧基，三氟甲基等; R9和R10表示H，烷基等; R 11和R 12中的任一个表示H，另一个表示烷基，R 13表示任选取代的碳环或杂环等，或R 11表示H，R 12和R 13结合在一起形成双环碳环。

    Multiple coding method and apparatus, multiple decoding method and apparatus, and information transmission system
    10.
    发明授权
    Multiple coding method and apparatus, multiple decoding method and apparatus, and information transmission system 有权
    多重编码方法和装置，多重解码方法和装置以及信息传输系统

    公开(公告)号：US06658605B1

    公开(公告)日：2003-12-02

    申请号：US09703638

    申请日：2000-11-02

    申请人： Hideo Yoshida ,  Takahiko Nakamura ,  Hachiro Fujita ,  Yoshikuni Miyata ,  Kazuo Kubo

    发明人： Hideo Yoshida ,  Takahiko Nakamura ,  Hachiro Fujita ,  Yoshikuni Miyata ,  Kazuo Kubo

    IPC分类号： G11C2900

    CPC分类号： H03M7/30 ,  H03M13/15 ,  H03M13/1515 ,  H03M13/2707 ,  H03M13/2721 ,  H03M13/29 ,  H03M13/6561

    摘要： A multiple coding apparatus comprises a first encoder for encoding a plurality of input sequences in parallel so as to generate a plurality of output coded sequences in parallel while adding an error-correcting bit sequence to each of the plurality of input sequences. An interleaving circuit interleaves the plurality of output coded sequences applied thereto in parallel from the first encoder without having to use any memory. The interleaving circuit permutes the plurality of input sequences on a bit-by-bit or symbol-by-symbol basis so as to generate a plurality of interleaved coded sequences in parallel. A second encoder then encodes the plurality of interleaved coded sequences applied thereto in parallel from the interleaving circuit so as to generate a plurality of output coded sequences in parallel while adding an error-correcting bit sequence to each of the plurality of interleaved coded sequences.

    摘要翻译： 多重编码装置包括：并行地编码多个输入序列的第一编码器，以便并行地产生多个输出编码序列，同时向多个输入序列中的每个输入序列添加纠错位序列。 交织电路将从第一编码器并行地施加到其上的多个输出编码序列进行交织，而不必使用任何存储器。 交织电路逐位或逐符号地排列多个输入序列，以便并行地生成多个交错编码序列。 然后，第二编码器对从交织电路并行施加到其上的多个交错编码序列进行编码，以便并行地产生多个输出编码序列，同时向多个交错编码序列中的每一个添加纠错位序列。