公开(公告)号：US12104192B2

公开(公告)日：2024-10-01

申请号：US17194222

申请日：2021-03-06

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sang Yup Lee ,  Dong In Kim ,  Tong Un Chae

IPC: C12N9/88 ,  C12N1/21 ,  C12P13/00 ,  C12P13/06 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N9/88 ,  C12P13/001 ,  C12P13/06 ,  C12Y401/01014

Abstract: Disclosed is a method of preparing primary amines. More particularly, disclosed are a mutant microorganism transformed with a gene encoding a valine decarboxylase and a method of preparing primary amines from amino acids using the mutant microorganism. The method has an effect of synthesizing, in an environmentally friendly manner, primary amines as precursors for pharmaceuticals and agricultural chemicals using microorganisms, as an alternative to conventional chemical synthesis methods.