DOSE-GUIDED DEFORMABLE IMAGE REGISTRATION

    公开(公告)号:US20220323789A1

    公开(公告)日:2022-10-13

    申请号:US17640074

    申请日:2020-08-28

    Abstract: The present invention relates to radiation therapy. In order to improve the accuracy in deformable image registration in radiation therapy planning, a method is provided that comprises a) receiving a dose distribution to be delivered during one or more treatment sessions according to a radiation therapy plan, b) receiving contours delineating at least one region of interest, ROI, of at least one of the medical images, c) receiving one or more treatment objectives associated with the at least one ROI that has delineated contours, d) determining one or more critical regions in at least one of the medical images, where a geometric error of the contours of the at least one ROI and/or an uncertainty in the electron density distribution leads to a violation of one or more treatment objectives with respect to the dose distribution, and e) improving the accuracy of a deformable image registration algorithm in the one or more critical regions for registering the at least two medical images, wherein the deformable image registration algorithm estimates a deformation between the at least two medical images.

    METHODS AND SYSTEMS FOR VALVE REGURGITATION ASSESSMENT

    公开(公告)号:US20220079551A1

    公开(公告)日:2022-03-17

    申请号:US17423892

    申请日:2020-02-04

    Abstract: The invention provides a method for assessing cardiac valve regurgitation. The method includes obtaining 4D ultrasound data of a region of interest, wherein the region of interest comprises a cardiac valve. The 4D ultrasound data comprises a time sequence of 3D ultrasound images comprising B-mode ultrasound data and color Doppler ultrasound data. Image stabilization is performed on the images of the time sequence of 3D ultrasound images and a dynamic jet is then segmented from the time sequence of stabilized 3D ultrasound images. A dynamic surface model is fit to the valve in the time sequence of stabilized 3D ultrasound images based on the segmented jet. The method further includes identifying a dynamic regurgitant orifice based on the applied surface model and the time sequence of stabilized 3D ultrasound images and fitting a flow convergence model to the time sequence of stabilized 3D ultrasound images based on the identified dynamic regurgitant orifice. A regurgitant flow is then estimated based on the identified regurgitant orifice.

Patent Agency Ranking