公开(公告)号：US20220413074A1

公开(公告)日：2022-12-29

申请号：US17781135

申请日：2020-12-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay NEHRKE ,  Peter Boernert ,  Jan Hendrik Wuelbern

IPC: G01R33/483 ,  G01R33/56

Abstract: Disclosed herein is a method of training a neural network (214) to perform a SENSE magnetic resonance imaging reconstruction. The method comprises receiving (100) initial training data, wherein the initial training data comprises sets of initial training complex channel images each paired with a predetermined number of initial ground truth images. The method further comprises generating (102) additional training data by performing data augmentation on the initial training data such that the data augmentation comprises adding a distinct phase offset to each of the set of initial training complex channel images during generation of the sets of additional training complex channel images. The method further comprises inputting (104) the sets of additional training complex channel images into the neural network and receiving in response a predetermined number of output training images and performing deep learning using the output training images.

公开(公告)号：US11226389B2

公开(公告)日：2022-01-18

申请号：US16339858

申请日：2017-10-09

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Karsten Sommer ,  Michael Gunter Helle ,  Thomas Erik Amthor ,  Peter Boernert

IPC: G01R33/563 ,  A61B5/00 ,  A61B5/055 ,  A61B5/026 ,  G01R33/56 ,  G06T7/00 ,  G01R33/561

Abstract: The invention provides for a method of operating a magnetic resonance imaging system for imaging a subject. The method comprises acquiring (700) tagged magnetic resonance data (642) and a first portion (644) of fingerprinting magnetic resonance data by controlling the magnetic resonance imaging system with tagging pulse sequence commands (100). The tagging pulse sequence commands comprise a tagging inversion pulse portion (102) for spin labeling a tagging location within the subject. The tagging pulse sequence commands comprise a background suppression portion (104). The background suppression portion comprises MRF pulse sequence commands for acquiring fingerprinting magnetic resonance data according to a magnetic resonance fingerprinting protocol. The tagging pulse sequence commands comprise an image acquisition portion (106). The method comprises acquiring (702) control magnetic resonance data (646) and a second portion (648) of the fingerprinting magnetic resonance data by controlling the magnetic resonance imaging system with control pulse sequence commands. The control pulse sequence commands comprise a control inversion pulse portion (202). The control pulse sequence commands comprise the background suppression portion (104′). The control pulse sequence commands comprise the image acquisition portion (106). The method comprises reconstructing (704) tagged magnitude images (650) using the tagged magnetic resonance data. The method comprises reconstructing (706) a control magnitude images (652) using the control magnetic resonance data. The method comprises constructing (708) an ASL image by subtracting the control magnitude images and the tagged magnitude images from each other. The method comprises reconstructing (710) a series of magnetic resonance fingerprinting images (656) using the first portion of the fingerprinting magnetic resonance data and/or the second portion of the fingerprinting magnetic resonance data. The method comprises generating (712) at least one magnetic resonance parametric map (658) by comparing the series of magnetic resonance fingerprinting images with a magnetic resonance fingerprinting dictionary.

公开(公告)号：US10330757B2

公开(公告)日：2019-06-25

申请号：US15544397

申请日：2016-01-21

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Ulrich Katscher ,  Jan Jakob Meineke ,  Holger Eggers ,  Peter Boernert

IPC: G01R33/44 ,  A61B5/055 ,  G01R33/24 ,  G01R33/48 ,  G01R33/565 ,  G01R33/56 ,  G01R33/54 ,  G01R33/28

Abstract: The invention provides for a magnetic resonance imaging system (100, 300, 100) for acquiring magnetic resonance data (110, 1104) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (136) for storing machine executable instructions (160, 162, 164, 166, 316) and pulse sequence data (140, 1102). The pulse sequence data comprises instructions for controlling the magnetic resonance imaging system to acquire magnetic resonance data according to a magnetic resonance imaging method. The magnetic resonance imaging system further comprises a processor (130) for controlling the magnetic resonance imaging system. Execution of the machine executable instructions causes the processor to: acquire (1200) the magnetic resonance data by controlling the magnetic resonance imaging system with the pulse sequence data; calculate (1202) a B0 inhomogeneity map (148) by analyzing the magnetic resonance data according to the magnetic resonance imaging method, calculate (1204) a B1 phase map (150) and/or a B1 amplitude map (1106) by analyzing the magnetic resonance data according to the magnetic resonance imaging method; and calculate (1206) a second derivative (1110) of the B1 phase map and/or a second derivative of the B1 magnitude map 1 and/or a second derivative of the B0 in homogeneity map in at least one predetermined direction. The second derivative is calculated using a corrected voxel size in the at least one predetermined direction, wherein the corrected voxel size is calculated using a correction factor calculated from the derivative of the B0 inhomogeneity map.

公开(公告)号：US09753111B2

公开(公告)日：2017-09-05

申请号：US14895319

申请日：2014-06-07

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Forthmann ,  Sascha Krueger ,  Tim Nielsen ,  Jurgen Erwin Rahmer ,  Peter Vernickel ,  Peter Boernert ,  Ulrich Katscher

IPC: G06K9/00 ,  G01R33/54 ,  G01B11/24 ,  G01G19/44 ,  G01R33/30 ,  G06T7/00 ,  H04N5/225 ,  G06T7/73 ,  G01R33/28

CPC classification number: G01R33/543 ,  G01B11/24 ,  G01G19/44 ,  G01R33/28 ,  G01R33/307 ,  G06T7/0012 ,  G06T7/73 ,  G06T2200/04 ,  G06T2207/10088 ,  G06T2207/30196 ,  H04N5/225

Abstract: A system and method determines an isocenter for an imaging scan. The method includes receiving, by a control panel, patient data generated by at least one sensor, the patient data corresponding to dimensions of a body of a patient. The method includes generating, by the control panel, model data as a function of the patient data, the model data representing the body of the patient. The method includes receiving, by the control panel, a target location on the model data, the target location corresponding to a desired position on the body of the patient for performing the imaging scan. The method includes determining, by the control panel, an isocenter for the imaging scan as a function of the target location.

公开(公告)号：US11978136B2

公开(公告)日：2024-05-07

申请号：US17299804

申请日：2019-11-26

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Arne Ewald ,  Nick Flaeschner ,  Bernhard Gleich ,  Ingmar Graesslin ,  Peter Boernert ,  Ingo Schmale ,  Johannes Adrianus Overweg

IPC: G06T11/00 ,  G01R33/48 ,  G01R33/56 ,  G01R33/565 ,  G06N3/044 ,  G06N3/045

CPC classification number: G06T11/008 ,  G01R33/4806 ,  G01R33/5608 ,  G01R33/56509 ,  G06N3/044 ,  G06N3/045 ,  G06T2210/41

Abstract: The invention provides for a medical imaging system (100, 400) comprising a memory (110) storing machine executable instructions (120) and a configured artificial neural network (122). The medical imaging system further comprises a processor (104) configured for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to receive (200) magnetic resonance imaging data (124), wherein the magnetic resonance imaging data is BOLD functional magnetic resonance imaging data descriptive of a time dependent BOLD signal (1100) for each of a set of voxels. Execution of the machine executable instructions further causes the processor to construct (202) a set of initial signals (126) by reconstructing the time dependent BOLD signal for each of the set of voxels using the magnetic resonance imaging data. Execution of the machine executable instructions further causes the processor to receive (204) a set of modified signals (128) in response to inputting the set of initial signals into the configured artificial neural network. The configured artificial neural network is configured for removing physiological artifacts from the set of initial signals.

公开(公告)号：US11867784B2

公开(公告)日：2024-01-09

申请号：US17614595

申请日：2020-06-03

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Boernert ,  Karsten Sommer ,  Christophe Michael Jean Schulke ,  Johan Samuel Van Den Brink

IPC: G01R33/48 ,  G01R33/561 ,  G01R33/565

CPC classification number: G01R33/4824 ,  G01R33/5611 ,  G01R33/56563

Abstract: The invention relates to a method of MR imaging of an object (10) positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient and high-quality non-Cartesian MR imaging, even in situations of strong B0 inhomogeneity. In accordance with the invention, the method comprises: —subjecting the object to an imaging sequence comprising at least one RF excitation pulse and modulated magnetic field gradients, —acquiring MR signals along at least one non-Cartesian k-space trajectory, —reconstructing an MR image from the acquired MR signals, and —detecting one or more mal-sampling artefacts caused by B0 inhomogeneity induced insufficient k-space sampling in the MR image using a deep learning network. Moreover, the invention relates to a MR device (1) and to a computer program.

公开(公告)号：US20230122915A1

公开(公告)日：2023-04-20

申请号：US17914435

申请日：2021-03-24

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Boernert

IPC: G01R33/565 ,  G01R33/48 ,  G01R33/56 ,  G06N3/08

Abstract: Abstract: Disclosed herein is a medical system comprising a memory (110) storing machine executable instructions (120) and a trained neural network (122). The trained neural network is configured to output corrected magnetic resonance image data (130) in response to receiving as input a set of magnetic resonance images (126) each having a different spatially constant frequency off-resonance factor. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) k-space data (124) acquired according to a magnetic resonance imaging protocol; reconstruct (202) a set of magnetic resonance images (126) according to the magnetic resonance imaging protocol, wherein each of the set of magnetic resonance images is reconstructed assuming a different spatially constant frequency off-resonance factor chosen from a list of frequency off-resonance factors (128); and receive (204) the corrected magnetic resonance image data in response to inputting the set of magnetic resonance images into the trained neural network.

公开(公告)号：US11241162B2

公开(公告)日：2022-02-08

申请号：US15303535

申请日：2015-03-31

Applicant: KONINKLIJKE PHILIPS N.V. ,  UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

Inventor： Nadine Gdaniec ,  Peter Boernert ,  Mariya Ivanova Doneva ,  Ivan Pedrosa

IPC: A61B5/055 ,  A61B5/00 ,  G01R33/565 ,  G06T7/00 ,  G01R33/563 ,  G01R33/56 ,  G01R33/48

Abstract: A method of operating a magnetic resonance imaging system (10) with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring (48) a first set of magnetic resonance image data (xpre) prior to administering a contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (52) a first image of the spatial distribution of fat (Ipre) of at least the portion of the subject of interest (20), acquiring (50) at least a second set of magnetic resonance image data (x2) of at least the portion of the subject of interest (20) after administering the contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (54) at least a second image of the spatial distribution of fat (I2ph) of at least the portion of the subject of interest (20), applying (56) an image registration method to the second image of the spatial distribution of fat (I2ph) with reference to the first image of the spatial distribution of fat (Ipre) for correcting a potential motion of the subject of interest (20); and a magnetic resonance imaging system (10) having a control unit (26) that is configured to carry out steps (56-64) of such a method; and a software module (44) for carrying out such a method, wherein the method steps (56-64) to be conducted are converted into a program code that is implementable in a memory unit (30) and is executable by a processor unit (32) of the magnetic resonance imaging system (10).

公开(公告)号：US10830856B2

公开(公告)日：2020-11-10

申请号：US16340492

申请日：2017-09-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Boernert ,  Miha Fuderer ,  Kay Nehrke ,  Klaas Pruessmann ,  Jurgen Edwin Rahmer ,  Bertram Wilm ,  Christian Stehning

IPC: G01V3/00 ,  G01R33/565 ,  G01R33/385 ,  G01R33/561 ,  G01R33/24

Abstract: A magnetic resonance imaging system includes a gradient system and a processor for controlling the magnetic resonance imaging system. Execution of machine executable instructions causes the magnetic resonance imaging system to: acquire by coil elements first magnetic resonance data simultaneously from a group of passive local probes, wherein the first group of passive local probes includes a plurality of passive local probes located spaced apart from each other; disentangle contributions to the first magnetic resonance data from the individual local probes, calculate for the magnetic resonance imaging system a gradient impulse response function of the gradient system using the first magnetic resonance data from the local probes; and determine correction factors using the gradient impulse response function

公开(公告)号：US10788556B2

公开(公告)日：2020-09-29

申请号：US16072940

申请日：2017-02-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Thomas Erik Amthor ,  Peter Koken ,  Karsten Sommer ,  Mariya Ivanova Doneva ,  Peter Boernert

IPC: G01R33/56 ,  G01R33/46 ,  G01R33/48 ,  G01R33/54 ,  G01R33/561

Abstract: A magnetic resonance imaging system (100) acquires magnetic resonance data (142) from a subject (118) within a measurement zone (108). Pulse sequence commands (140) control the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting protocol. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to repeatedly generate an RF pulse train (300) and acquire the magnetic resonance data as multiple k-space traces. The machine executable instructions causes the processor to: sequentially acquire (200) the multiple k-space traces of magnetic resonance data by controlling the magnetic resonance imaging system with pulse sequence commands and calculate (202) the abundance of each of a set of predetermined substances for k-space traces that are acquired after a predetermined number of k-space traces of the multiple k-space traces has been acquired and the acquired magnetization has reached a steady state. The abundance of each of a set of predetermined substances is determined by comparing the magnetic resonance data with a steady state magnetic resonance fingerprinting dictionary (144) which contains a listing of calculated magnetic resonance signals in response to the RF pulse train for a set of predetermined substances.