公开(公告)号：US06317206B1

公开(公告)日：2001-11-13

申请号：US09286718

申请日：1999-04-06

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01N2164

CPC分类号： G01N21/648 ,  G01N21/6452

摘要： The present invention relates to a device for the detection of a fluorescent dye in samples, comprising a device for exciting the fluorescent dye to be detected, said device comprising a surface provided for the application of samples and an excitation light coupling device by means of which excitation light from a predefined direction of impingement can be coupled into the device in such a way that, by means of an evanescent field of the coupled light, the fluorescent dye to be detected can be excited in the samples applied, and further comprising a means for the detection of the fluorescent light emitted by the fluorescent dye to be detected. The present invention is characterized in that the device for exciting the fluorescent dye to be detected is provided in such a way that the surface to which the samples are to be applied is movable relative to the direction of impingement so as to excite the fluorescent dye to be detected in different subsections of said surface.

摘要翻译： 本发明涉及一种用于检测样品中的荧光染料的装置，包括用于激发待检测的荧光染料的装置，所述装置包括用于施加样品的表面和激发光耦合装置，通过该装置 来自预定的冲击方向的激发光可以以这样的方式耦合到装置中：借助于耦合光的消逝场，待检测的荧光染料可以在施加的样品中被激发，并且还包括一种装置 用于检测由待检测的荧光染料发出的荧光。 本发明的特征在于，用于激发要检测的荧光染料的装置被设置成使得要施加样品的表面相对于冲击方向是可移动的，以便将荧光染料激发到 在所述表面的不同子部分中被检测。

公开(公告)号：US5028800A

公开(公告)日：1991-07-02

申请号：US537964

申请日：1990-07-19

申请人： Jurgen Wulf ,  Werner Lahmann

发明人： Jurgen Wulf ,  Werner Lahmann

IPC分类号： G01J3/42 ,  G01J3/08 ,  G01J3/10 ,  G01N21/31 ,  G02B26/04

CPC分类号： G01J3/08 ,  G02B26/04 ,  G01J2003/106

摘要： In a double-beam photometer comprising a light source providing a light beam, detector means, a sample area, optical means for guiding the light beam as a measuring light beam through the sample area onto the detector means, means for guiding the same light beam as a reference light beam onto the detector means while avoiding the sample area, and chopper means disposed in a splitting location for splitting the light beam into the measuring light beam, which are combined into one path of rays in a recombination location, after the measuring light beam has passed through the sample area, with the splitting location and the recombination location being spatially close to each other. The chopper means has a single chopper which simultaneously effects the splitting and the combination of the measuring and reference light beams.

摘要翻译： 在包括提供光束的光源的双光束光度计中，检测器装置，样本区域，用于将通过样本区域的测量光束的光束引导到检测器装置上的光学装置，用于引导相同光束 作为参考光束在检测器装置上同时避开样本区域;以及斩波装置，设置在分离位置，用于将光束分裂成测量光束，该测量光束在测量之后被组合成一条光线路径 光束已经通过样本区域，分割位置和复合位置在空间上彼此接近。 斩波器装置具有同时实现测量和参考光束的分离和组合的单个斩波器。

公开(公告)号：US06632401B1

公开(公告)日：2003-10-14

申请号：US09286849

申请日：1999-04-06

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01N2164

CPC分类号： G01N21/643 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6469 ,  G01N2201/065

摘要： The present invention relates to a device for the detection of a fluorescent dye in a sample, comprising a radiation source with the aid of which light for exciting the fluorescent dye to be detected can be transmitted into the sample applied to a carrier, and a detecting device for detecting fluorescent light which has been emitted by the fluorescent dye to be detected. The present invention is characterized by a hollow space having an internal high-reflectance surface, a first aperture directed towards the sample, and a second aperture located opposite the detecting device.

摘要翻译： 本发明涉及一种用于检测样品中的荧光染料的装置，其包括一个辐射源，借助于该光源可以将用于激发要检测的荧光染料的光透射到施加到载体上的样品中， 用于检测由待检测的荧光染料发射的荧光的装置。 本发明的特征在于具有内部高反射率表面，朝向样品的第一孔和与检测装置相对的第二孔的中空空间。

公开(公告)号：US20050274907A1

公开(公告)日：2005-12-15

申请号：US11193848

申请日：2005-07-28

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01J3/02 ,  G01J3/443 ,  G01N21/64 ,  G01T1/00

CPC分类号： G01N21/643 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6469 ,  G01N2201/065

摘要： The present invention relates to a device for the detection of a fluorescent dye in a sample, comprising a radiation source means with the aid of which light for exciting the fluorescent dye to be detected can be transmitted into the sample applied to a carrier, and a detecting means for detecting fluorescent light which has been emitted by the fluorescent dye to be detected. The present invention is characterized by a hollow space having an internal high-reflectance surface, a first aperture directed towards the sample, and a second aperture located opposite the detecting means.

摘要翻译： 本发明涉及一种用于检测样品中的荧光染料的装置，其包括用于激发要检测的荧光染料的光的辐射源装置可以传输到施加到载体的样品中，并且 用于检测由待检测的荧光染料发射的荧光的检测装置。 本发明的特征在于具有内部高反射率表面，朝向样品的第一孔和与检测装置相对的第二孔的中空空间。

公开(公告)号：US5066124A

公开(公告)日：1991-11-19

申请号：US513395

申请日：1990-04-23

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01N21/31

CPC分类号： G01N21/3103 ,  G01N2021/3114

摘要： In an atomic absorption spectrophotometer for multielement analysis, the light from a plurality of light sources each of which emits the resonance lines of one associated looked-for element is superimposed into a single light beam by means of interconnected light guides. The light is directed onto a polychromator 64 via an optical coupler.

摘要翻译： 在用于多元素分析的原子吸收分光光度计中，来自多个光源的光通过相互连接的光导被叠加到单个光束中，每个光源发射一个相关联的寻找元件的谐振线。 光通过光耦合器被引导到多色板64上。

公开(公告)号：US20090162939A1

公开(公告)日：2009-06-25

申请号：US12397202

申请日：2009-03-03

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01N21/76

CPC分类号： G01N21/643 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6469 ,  G01N2201/065

摘要： The present invention relates to a device for the detection of a fluorescent dye in a sample, comprising a radiation source means with the aid of which light for exciting the fluorescent dye to be detected can be transmitted into the sample applied to a carrier, and a detecting means for detecting fluorescent light which has been emitted by the fluorescent dye to be detected. The present invention is characterized by a hollow space having an internal high-reflectance surface, a first aperture directed towards the sample, and a second aperture located opposite the detecting means.

摘要翻译： 本发明涉及一种用于检测样品中的荧光染料的装置，其包括用于激发要检测的荧光染料的光的辐射源装置可以传输到施加到载体的样品中，并且 用于检测由待检测的荧光染料发射的荧光的检测装置。 本发明的特征在于具有内部高反射率表面，朝向样品的第一孔和与检测装置相对的第二孔的中空空间。

公开(公告)号：US5495331A

公开(公告)日：1996-02-27

申请号：US391397

申请日：1995-02-27

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01J3/18 ,  G01J3/28

CPC分类号： G01J3/04 ,  G01J3/18 ,  G01J2003/1286

摘要： The present invention refers to a dual-beam polychromator comprising a reflecting dispersion grating, a first entrance slit for a first ray bundle, a second entrance slit for a second ray bundle and first and second detector devices respectively used for simultaneously detecting the spectra of the first and second ray bundles diffracted at the dispersion grating. Dual-beam polychromators which are known according to the prior art and which have their respective entrance slits arranged directly adjacent the detector devices of the other channel cause substantial structural difficulties with regard to the mechanical provision of the respective components. In accordance with the present invention, this problem is solved by a dual-beam polychromator of the above-mentioned type, which is characterized by the features that a concave mirror means provided with an opening is located opposite the dispersion grating, said concave mirror means being adapted to be used for focussing the light, which has been diffracted at the dispersion grating, onto said first and second detector devices, and that each of the ray bundles coming from the first and second entrance slits are adapted to be directed through said opening onto the grating.

摘要翻译： 本发明涉及一种双光束多色分光器，包括反射色散光栅，用于第一光束的第一入射狭缝，用于第二光束的第二入射狭缝，以及分别用于同时检测第二光束的光谱的第一和第二检测器装置 第一和第二束束在分散光栅处衍射。 根据现有技术已知并具有直接与另一通道的检测器装置相邻布置的各自的入口狭缝的双光束多色分色器在相应部件的机械提供方面引起相当大的结构困难。 根据本发明，这个问题是通过上述类型的双光束多色分光器来解决的，其特征在于具有开口的凹面镜装置位于与分散光栅相对的特征，所述凹面镜装置 适于用于将已经在分散光栅处衍射的光聚焦到所述第一和第二检测器装置上，并且来自第一和第二入口狭缝的每个光束束适于被引导通过所述开口 到光栅上。

公开(公告)号：US5157456A

公开(公告)日：1992-10-20

申请号：US625277

申请日：1990-12-10

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01J3/12 ,  G01J3/18

CPC分类号： G01J3/18 ,  G01J2003/1814

摘要： A double monochromator comprises an inlet slit 20, which is imaged in the plane of an intermediate slit 34 through a first grating monochromator 36. The intermediate slit 34 is imaged in the plane of the outlet slit 34 through a second grating monochromator 58 identical with the first grating monochromator 36. Deflecting mirrors 64 and 66 can be moved into the path of rays to enable such a double monochromator to be optionally used as a single monochromator with increased light flux. An additional slit is arranged between the deflecting mirrors 64 and 66. The arrangement is such so that essentially identical beam geometries result at the outlet in both of the operation modes.

摘要翻译： 双单色器包括入口狭缝20，其通过第一光栅单色仪36在中间狭缝34的平面中成像。中间狭缝34通过与第一光栅单色仪58相同的第二光栅单色仪58在出口狭缝34的平面中成像 第一光栅单色仪36.偏转镜64和66可以移动到光线的路径中，以使得这种双单色器可以任选地用作具有增加的光通量的单个单色仪。 在偏转镜64和66之间设置一个附加的狭缝。这种布置使得在两种操作模式下在出口处产生基本上相同的光束几何形状。

公开(公告)号：US5118188A

公开(公告)日：1992-06-02

申请号：US661731

申请日：1991-02-26

申请人： Jurgen Wulf

发明人： Jurgen Wulf

IPC分类号： G01J1/02 ,  G01J1/16 ,  G01J1/44

CPC分类号： G01J1/16 ,  G01J2001/4453

摘要： A photomultiplier (10) with an elongated rectangular, cathode (20) tilted with respect to the inlet opening (14) is alternately illuminated by a measuring light beam (36) and a reference light beam (40). The measuring light beam (36) and the reference light beam (40) extend in a plane parallel to the longitudinal sides of the cathode (20) and impinge upon the cothode (20), such that they illuminate the same areas of the cathode (20).

摘要翻译： 具有相对于入口开口（14）倾斜的细长矩形阴极（20）的光电倍增管（10）由测量光束（36）和参考光束（40）交替照射。 测量光束（36）和参考光束（40）在平行于阴极（20）的纵向侧面的平面中延伸并撞击在阴极（20）上，使得它们照射阴极的相同区域 20）。