公开(公告)号：US20090093933A1

公开(公告)日：2009-04-09

申请号：US12287444

申请日：2008-10-08

Applicant: Jong Dae Kim ,  Kwi Han Chae ,  Sang Kil Lee ,  Jae Kwan Lee

Inventor： Jong Dae Kim ,  Kwi Han Chae ,  Sang Kil Lee ,  Jae Kwan Lee

IPC: G06F19/00

CPC classification number: B60W50/00 ,  B60W10/00 ,  B60W10/184 ,  B60W10/20 ,  B60W10/22

Abstract: The present invention relates to an integrated safety control system for vehicles. In particular, the present invention includes a sensor unit, an actuating unit, an actuating control unit, and an integrated control unit. The sensor unit includes a plurality of sensors for outputting sensed signals required for chassis control and Advanced Safety Vehicle (ASV) control of the vehicle. The actuating unit includes a plurality of actuating subunits for performing the chassis control and the ASV control. The actuating control unit includes a plurality of actuating control subunits provided for the respective actuating subunits, and configured to operate the respective actuating subunits. The integrated control unit compares and analyzes the sensed signals and selectively controls the respective actuating subunits so as to perform chassis control and ASV control in an integrated control manner.

Abstract translation: 本发明涉及一种用于车辆的综合安全控制系统。 特别地，本发明包括传感器单元，致动单元，致动控制单元和集成控制单元。 传感器单元包括用于输出车辆控制和车辆的高级安全车辆（ASV）控制所需的感测信号的多个传感器。 致动单元包括用于执行底盘控制和ASV控制的多个致动子单元。 致动控制单元包括为相应的致动子单元提供的多个致动控制子单元，并被配置为操作相应的致动子单元。 集成控制单元比较和分析所感测的信号，并且选择性地控制相应的致动子单元，以便以集成的控制方式执行底盘控制和ASV控制。

公开(公告)号：US20120220468A1

公开(公告)日：2012-08-30

申请号：US13392400

申请日：2010-09-02

Applicant: Jong Yoon Chun ,  In Taek Hwang ,  Sang Kil Lee

Inventor： Jong Yoon Chun ,  In Taek Hwang ,  Sang Kil Lee

IPC: C40B20/04 ,  C07H21/04 ,  C07H1/00 ,  G01N21/64

CPC classification number: C07H21/00 ,  C12Q1/6823 ,  C12Q2565/1015 ,  C12Q2561/101 ,  C12Q2525/161

Abstract: The present invention relates to a target discriminative probe (TD probe) and its uses or applications. The TD probe is hybridized with a target nucleic acid sequence through both of the 5′-second hybridization portion and the 3′-first hybridization portion. When the TD probe is hybridized with a non-target nucleic acid sequence, both the 5′-second hybridization portion and the separation portion are not hybridized with the non-target nucleic acid sequence such that both portions form a single strand due to its low Tm value. As such, the TD probe exhibits distinctly different hybridization patterns for each of the target and the non-target nucleic acid sequence, discriminating the target nucleic acid sequence from the non-target nucleic acid sequence with much higher specificity.

Abstract translation: 本发明涉及目标鉴别探针（TD探针）及其用途或应用。 TD探针通过5'-第二杂交部分和3'-第一杂交部分与靶核酸序列杂交。 当TD探针与非靶核酸序列杂交时，5'-第二杂交部分和分离部分都不与非靶核酸序列杂交，使得两部分由于其低部分形成单链 Tm值。 因此，TD探针对靶和非靶核酸序列中的每一个显示明显不同的杂交模式，以非常高的特异性区分靶核酸序列与非靶核酸序列。

公开(公告)号：US20100102976A1

公开(公告)日：2010-04-29

申请号：US12345542

申请日：2008-12-29

Applicant: Wook Ryun Lee ,  Jun Shin Lee ,  Yong Chae Bae ,  Byong Han Kim ,  Sang Kil Lee

Inventor： Wook Ryun Lee ,  Jun Shin Lee ,  Yong Chae Bae ,  Byong Han Kim ,  Sang Kil Lee

IPC: G08B21/18 ,  G01M7/00

CPC classification number: G01H1/003

Abstract: The present invention provides a system and method for monitoring vibration of a power transformer. The system comprises at least one vibration sensor operably mounted to the outer case of a transformer for sensing vibration of the power transformer; a spectrum analyzer for processing the vibration signal from the vibration sensor, the spectrum analyzer generating a frequency spectrum of the vibration signal and calculating a velocity rating from the frequency spectrum; a diagnosing means for evaluating the velocity rating of the vibration signal, the diagnosing means assigning a vibration grade for each velocity rating, the diagnosing means finding the maximum velocity rating; and a means for dispatching a control message to an operator when the maximum velocity rating reaches a threshold value. It can be appreciated that the mechanical health of a large-sized transformer can be managed in a systematic and efficient manner during its operation. This system can prevent accidents due to the mechanical failure of the transformer or diagnosing failure of the transformer itself during its operation. This system also can provide useful information to determine when the transformer has to be replaced and further to predict what the expected lifespan of the transformer will be.

Abstract translation: 本发明提供了一种用于监测电力变压器的振动的系统和方法。 该系统包括至少一个振动传感器，其可操作地安装到变压器的外壳上，用于感测电力变压器的振动; 用于处理来自振动传感器的振动信号的频谱分析器，频谱分析仪产生振动信号的频谱并从频谱计算速度等级; 用于评估振动信号的速度等级的诊断装置，为每个速度等级分配振动等级的诊断装置，找到最大速度等级的诊断装置; 以及当最大速度等级达到阈值时向操作者发送控制消息的装置。 可以理解，在其操作期间，可以以系统和有效的方式管理大型变压器的机械健康。 该系统可以防止变压器机械故障引起的事故或诊断变压器本身在运行过程中的故障。 该系统还可以提供有用的信息来确定何时必须更换变压器，并进一步预测变压器的预期使用寿命。

公开(公告)号：US08685440B2

公开(公告)日：2014-04-01

申请号：US12375739

申请日：2007-08-01

Applicant: Joon Pio Hong ,  Sang Kil Lee ,  Won Chul Kim ,  Chae Ha Yoon ,  Sang Wook Lee ,  Kyeong Sun Shin ,  Seung Kook Park

Inventor： Joon Pio Hong ,  Sang Kil Lee ,  Won Chul Kim ,  Chae Ha Yoon ,  Sang Wook Lee ,  Kyeong Sun Shin ,  Seung Kook Park

IPC: A61K36/00 ,  A61K9/127 ,  A61K8/14 ,  A61K8/55

CPC classification number: A61K9/1271 ,  A61K8/14 ,  A61K8/553 ,  A61K9/1277 ,  A61K2800/413 ,  A61Q19/00 ,  B82Y5/00

Abstract: The present invention relates to a nanoliposome comprising a liposome membrane containing esterified lecithin, and one or more physiologically active ingredients included in inner space of the liposome membrane; a method for preparing the same; and a composition for preventing or treating skin diseases, comprising the same. The nanoliposome according to the present invention has long-term stability and uniformity, and so can be used to prepare a composition for skin having excellent moisturizing and penetrating properties, such as cosmetics, medicament for treating skin diseases, or the like. In particular, the present composition for preventing or treating skin diseases comprises epidermal growth factor included in the nanoliposome, thereby showing an excellent effect of stimulating skin-penetration and good pharmaceutical stability. Also, the esterified lecithin used in preparing liposome can provide effects of softening skin and stimulating skin-penetration, thereby enhancing the penetration of epidermal growth factor and natural extract into skin, as well as additional moisturizing effect which is advantageous in treating skin diseases. Further, since the present composition comprises nanoliposome prepared by containing esterified lecithin in liposome membrane, the conventional problems of heating and dispersing active ingredients at high temperature (70° C. or more), low stability and uniformity, or the like can be solved.

Abstract translation: 本发明涉及包含含有酯化卵磷脂的脂质体膜和包含在脂质体膜的内部空间中的一种或多种生理活性成分的纳米脂质体， 其制备方法; 以及用于预防或治疗皮肤病的组合物。 根据本发明的纳米脂质体具有长期的稳定性和均匀性，因此可以用于制备具有优异的保湿和渗透性的皮肤组合物，例如化妆品，用于治疗皮肤病的药物等。 特别地，本发明的皮肤病预防或治疗组合物包括纳米脂质体中所含的表皮生长因子，因此显示刺激皮肤渗透和良好药物稳定性的优异效果。 此外，用于制备脂质体的酯化卵磷脂可以提供软化皮肤和刺激皮肤渗透的作用，从而增强表皮生长因子和天然提取物对皮肤的渗透性，以及有利于治疗皮肤疾病的额外的保湿效果。 此外，由于本发明的组合物包含通过在脂质体膜中含有酯化的卵磷脂而制备的纳米脂质体，因此可以解决在高温（70℃以上）下加热分散有效成分的常规问题，稳定性和均匀性低等。

公开(公告)号：US20090263473A1

公开(公告)日：2009-10-22

申请号：US12375739

申请日：2007-08-01

Applicant: Joon Pio Hong ,  Sang Kil Lee ,  Won Chul Kim ,  Chae Ha Yoon ,  Sang Wook Lee ,  Kyeong Sun Shin ,  Seung Kook Park

Inventor： Joon Pio Hong ,  Sang Kil Lee ,  Won Chul Kim ,  Chae Ha Yoon ,  Sang Wook Lee ,  Kyeong Sun Shin ,  Seung Kook Park

IPC: A61K9/127 ,  A61K38/43 ,  A61K36/00

CPC classification number: A61K9/1271 ,  A61K8/14 ,  A61K8/553 ,  A61K9/1277 ,  A61K2800/413 ,  A61Q19/00 ,  B82Y5/00

Abstract: The present invention relates to a nanoliposome comprising a liposome membrane containing esterified lecithin, and one or more physiologically active ingredients included in inner space of the liposome membrane; a method for preparing the same; and a composition for preventing or treating skin diseases, comprising the same. The nanoliposome according to the present invention has long-term stability and uniformity, and so can be used to prepare a composition for skin having excellent moisturizing and penetrating properties, such as cosmetics, medicament for treating skin diseases, or the like. In particular, the present composition for preventing or treating skin diseases comprises epidermal growth factor included in the nanoliposome, thereby showing an excellent effect of stimulating skin-penetration and good pharmaceutical stability. Also, the esterified lecithin used in preparing liposome can provide effects of softening skin and stimulating skin-penetration, thereby enhancing the penetration of epidermal growth factor and natural extract into skin, as well as additional moisturizing effect which is advantageous in treating skin diseases. Further, since the present composition comprises nanoliposome prepared by containing esterified lecithin in liposome membrane, the conventional problems of heating and dispersing active ingredients at high temperature (70° C. or more), low stability and uniformity, or the like can be solved.

Abstract translation: 本发明涉及包含含有酯化卵磷脂的脂质体膜和包含在脂质体膜的内部空间中的一种或多种生理活性成分的纳米脂质体， 其制备方法; 以及用于预防或治疗皮肤病的组合物。 根据本发明的纳米脂质体具有长期的稳定性和均匀性，因此可以用于制备具有优异的保湿和渗透性的皮肤组合物，例如化妆品，用于治疗皮肤病的药物等。 特别地，本发明的皮肤病预防或治疗组合物包括纳米脂质体中所含的表皮生长因子，因此显示刺激皮肤渗透和良好药物稳定性的优异效果。 此外，用于制备脂质体的酯化卵磷脂可以提供软化皮肤和刺激皮肤渗透的作用，从而增强表皮生长因子和天然提取物对皮肤的渗透性，以及有利于治疗皮肤疾病的额外的保湿作用。 此外，由于本发明的组合物包含通过在脂质体膜中含有酯化的卵磷脂而制备的纳米脂质体，因此可以解决在高温（70℃以上）下加热分散有效成分的常规问题，稳定性和均匀性低等。

公开(公告)号：US20090047331A1

公开(公告)日：2009-02-19

申请号：US12093551

申请日：2006-10-27

Applicant: Sun Hee Kim ,  Sang Kil Lee ,  Min Suk Lee ,  Joon Pio Hong

Inventor： Sun Hee Kim ,  Sang Kil Lee ,  Min Suk Lee ,  Joon Pio Hong

IPC: A61K9/70 ,  A61L15/00 ,  A61P17/02

CPC classification number: A61L26/0066 ,  A61L15/28 ,  A61L26/0023 ,  A61L26/0095 ,  C08L5/08

Abstract: The present invention relates to a sustained release film formulation for healing wound comprising epidermal growth factor, chitosan, viscosity modifiers, plasticizers, and stabilizers. Specifically, the present invention relates to a sustained release film formulation for healing wound comprising epidermal growth factor as an effective ingredient and chitosan as a main base, and additionally comprising one or more antioxidants selected from the group consisting of EDTA and vitamin C; one or more viscosity modifiers selected from the group consisting of hydroxypropylmethylcellulose, gellan gum and pullulan; and one or more plasticizers selected from the group consisting of glycerin, propylene glycol, polyethylene glycol, polyvinyl alcohol and polyvinylpyrrolidone thereto. When the present film is attached to wound site, it absorbs exudation from wound site, and so is changed to hydrogel to keep wound site humid, which is good for wound-healing. And, the present film has superior attachment property to human body, and antifungal activity. Thus, the present film has more merits than simple ointment/cream formulation.

Abstract translation: 本发明涉及用于治疗伤口的持续释放膜制剂，其包括表皮生长因子，壳聚糖，粘度调节剂，增塑剂和稳定剂。 具体地，本发明涉及一种用于治疗伤口的持续释放膜制剂，其包含表皮生长因子作为有效成分和壳聚糖作为主要基质，并且还包含一种或多种选自EDTA和维生素C的抗氧化剂; 选自羟丙基甲基纤维素，结冷胶和支链淀粉的一种或多种粘度调节剂; 和一种或多种选自甘油，丙二醇，聚乙二醇，聚乙烯醇和聚乙烯吡咯烷酮的增塑剂。 当本膜附着于伤口部位时，吸收伤口部位的渗出物，因此变为水凝胶，保持伤口部位湿润，有利于伤口愈合。 而且，本发明的膜具有优异的人体附着性和抗真菌活性。 因此，本发明的薄膜比简单的软膏/霜剂具有更多的优点。

公开(公告)号：US09333438B2

公开(公告)日：2016-05-10

申请号：US14702105

申请日：2015-05-01

Applicant: Sang Kil Lee ,  Young Soon Kim

Inventor： Sang Kil Lee ,  Young Soon Kim

IPC: A63H33/08 ,  A63H33/06

CPC classification number: A63H33/065 ,  A63H33/086

Abstract: A block studying tool for an infant, includes: a block body having a hexahedral shape, a lower portion of which is opened; and a plurality of unit assembling portions disposed to protrude from an upper portion of the block body upward and disposed to be spaced a predetermined distance apart from each other, wherein a divider is disposed at an inside of the lower portion of the block body and forms an assembling space in which the plurality of unit assembling portions of the adjacent block body are to be assembled according to positions.

Abstract translation: 一种用于婴儿的块学习工具，包括：具有六面体形状的块体，其下部打开; 以及多个单元组装部，其设置成从所述块体的上部向上突出并设置成彼此隔开预定距离，其中分隔件设置在所述块体的下部的内侧，并形成 根据位置组装相邻块体的多个单元组装部的组装空间。

公开(公告)号：US06780607B2

公开(公告)日：2004-08-24

申请号：US09792647

申请日：2001-02-23

Applicant: Cha Yong Choi ,  Sang Hyeon Kang ,  Taek Jin Kang ,  Ji Hyoung Woo ,  Sang Kil Lee ,  Seung Woo Cho

Inventor： Cha Yong Choi ,  Sang Hyeon Kang ,  Taek Jin Kang ,  Ji Hyoung Woo ,  Sang Kil Lee ,  Seung Woo Cho

IPC: C12P2106

CPC classification number: C12P21/005 ,  C07K14/505

Abstract: The present invention relates to methods of production of the completely post-translationally modified protein by combination of cell-free protein synthesis and cell-free co- and post-translational modification. Previous cell-free protein synthesis system has only been capable of producing partially post-translationally modified protein but the present invention employs a co- and post-translational modification machinery that produces completely post-translationally modified protein.

Abstract translation: 本发明涉及通过无细胞蛋白质合成和无细胞共转移和翻译后修饰的组合生产完全翻译后修饰的蛋白质的方法。 以前的无细胞蛋白质合成系统仅能够产生部分翻译后修饰的蛋白质，但是本发明使用产生完全翻译后修饰的蛋白质的共翻译和翻译后修饰机制。