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公开(公告)号：US08299045B2
公开(公告)日：2012-10-30
申请号：US13217518
申请日：2011-08-25
Applicant: John J. Rossi , Nan-Sook Lee
Inventor： John J. Rossi , Nan-Sook Lee
IPC: C12N15/11
CPC classification number: C07K14/005 , C12N15/111 , C12N15/1132 , C12N15/85 , C12N15/86 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12N2710/10322
Abstract: An adenoviral VA1 Pol III expression system for RNAi expression is provided.
Abstract translation: 提供了用于RNAi表达的腺病毒VA1 Pol III表达系统。
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Patent Agency Ranking
2.发明授权Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules 有权用于在哺乳动物细胞中产生干扰RNA分子的方法和用于这种分子的治疗用途公开(公告)号：US08106181B2
公开(公告)日：2012-01-31
申请号：US12709925
申请日：2010-02-22
Applicant: John J. Rossi , Nan-Sook Lee
Inventor： John J. Rossi , Nan-Sook Lee
CPC classification number: C12Q1/6876 , C12N15/111 , C12N15/113 , C12N15/1132 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12Q2600/178
Abstract: Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided.
Abstract translation: 提供了在哺乳动物细胞中产生干扰RNA分子的方法。 还提供了表达分子的治疗用途，包括抑制HIV的表达。
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公开(公告)号：US08017759B2
公开(公告)日：2011-09-13
申请号：US10629895
申请日：2003-07-30
Applicant: John J. Rossi , Nan-Sook Lee
Inventor： John J. Rossi , Nan-Sook Lee
IPC: C07H21/04
CPC classification number: C07K14/005 , C12N15/111 , C12N15/1132 , C12N15/85 , C12N15/86 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12N2710/10322
Abstract: An adenoviral VA1 Pol III expression system for RNAi expression is provided.
Abstract translation: 提供了用于RNAi表达的腺病毒VA1 Pol III表达系统。
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4.发明授权Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules 有权用于在哺乳动物细胞中产生干扰RNA分子的方法和用于这种分子的治疗用途公开(公告)号：US07820632B2
公开(公告)日：2010-10-26
申请号：US10365643
申请日：2003-02-13
Applicant: John J. Rossi , Nan-Sook Lee
Inventor： John J. Rossi , Nan-Sook Lee
CPC classification number: C12Q1/6876 , C12N15/111 , C12N15/113 , C12N15/1132 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12Q2600/178
Abstract: Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided.
Abstract translation: 提供了在哺乳动物细胞中产生干扰RNA分子的方法。 还提供了表达分子的治疗用途，包括抑制HIV的表达。
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5.发明授权Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules 有权用于在哺乳动物细胞中产生干扰RNA分子的方法和用于这种分子的治疗用途公开(公告)号：US08076071B2
公开(公告)日：2011-12-13
申请号：US12881509
申请日：2010-09-14
Applicant: John J. Rossi , Nan-Sook Lee
Inventor： John J. Rossi , Nan-Sook Lee
CPC classification number: C12Q1/6876 , C12N15/111 , C12N15/113 , C12N15/1132 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12Q2600/178
Abstract: Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided.
Abstract translation: 提供了在哺乳动物细胞中产生干扰RNA分子的方法。 还提供了表达分子的治疗用途，包括抑制HIV的表达。
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公开(公告)号：US20050074887A1
公开(公告)日：2005-04-07
申请号：US10629895
申请日：2003-07-30
Applicant: John Rossi , Nan-Sook Lee
Inventor： John Rossi , Nan-Sook Lee
IPC: C07K14/075 , C12N15/11 , C12N15/113 , C12N15/861 , A61K48/00
CPC classification number: C07K14/005 , C12N15/111 , C12N15/1132 , C12N15/85 , C12N15/86 , C12N2310/111 , C12N2310/14 , C12N2310/53 , C12N2330/30 , C12N2710/10322
Abstract: An adenoviral VA1 Pol III expression system for RNAi expression is provided.
Abstract translation: 提供了用于RNAi表达的腺病毒VA1 Pol III表达系统。
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