公开(公告)号：US20210268104A1

公开(公告)日：2021-09-02

申请号：US17323082

申请日：2021-05-18

申请人： Janssen Sciences Ireland Unlimited Company ,  Bavarian Nordic A/S

发明人： Daniel BODEN ,  Helen HORTON ,  Jean-Marc Edmond Fernand Marie NEEFS ,  Soumitra ROY ,  Jerôme Hubertina Henricus Victor CUSTERS ,  Roland Christian ZAHN ,  Markus KALLA

IPC分类号： A61K39/29 ,  C12N15/86 ,  A61K39/12

摘要： Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

公开(公告)号：US20190184011A1

公开(公告)日：2019-06-20

申请号：US16223400

申请日：2018-12-18

申请人： Janssen Sciences Ireland Unlimited Company ,  Bavarian Nordic A/S

发明人： Daniel BODEN ,  Helen HORTON ,  Jean-Marc Edmond Fernand Marie NEEFS ,  Soumitra ROY ,  Jerôme Hubertina Henricus Victor CUSTERS ,  Roland Christian ZAHN ,  Markus KALLA

IPC分类号： A61K39/29 ,  C12N15/86

CPC分类号： A61K39/292 ,  C12N15/86 ,  C12N2710/24143 ,  C12N2730/10134

摘要： Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

公开(公告)号：US20190142933A1

公开(公告)日：2019-05-16

申请号：US16098303

申请日：2017-05-01

申请人： Janssen Vaccines & Prevention B.V. ,  Bavarian Nordic A/S

发明人： Evelien M. BUNNIK ,  Jerôme H.h.v. CUSTERS ,  Gerrit C. SCHEPER ,  Selina KHAN ,  Markus KALLA ,  Katrin WEIDNER

IPC分类号： A61K39/295

摘要： Vectors, vaccines, vaccine compositions and vaccine combinations for use as therapeutics against HPV18 and/or HPV16 are described.