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公开(公告)号：US20150087596A1
公开(公告)日：2015-03-26
申请号：US14399088
申请日：2013-03-15
Applicant: JANSSEN BIOTECH, INC.
Inventor： William Eckert , Mack Flinspach , Michael Hunter , Yi Liu , Robert Neff , Alan Wickenden , Alan Gibbs
IPC: C07K14/435
CPC classification number: C07K14/43518 , A61K38/00
Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, methods of making and using the foregoing, and methods of alleviating pain with peptide inhibitors of Nav1.7.
Abstract translation: 本发明涉及Huwoxin-IV变体，编码它们的多核苷酸，制备和使用前述物质的方法以及使用Nav1.7肽抑制剂减轻疼痛的方法。
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公开(公告)号：US09102751B2
公开(公告)日：2015-08-11
申请号：US13833555
申请日：2013-03-15
Applicant: Janssen Biotech, Inc.
Inventor： Mack Flinspach , Michael Hunter , Yi Liu , Robert Neff , Alan Wickenden , Alan Gibbs
IPC: A61K38/00 , A61P3/04 , A61P25/00 , A61P23/00 , C07K14/435
CPC classification number: C07K14/43518 , A61K38/00
Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.
Abstract translation: 本发明涉及Huwentoxin-IV变体，编码它们的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：US20130310324A1
公开(公告)日：2013-11-21
申请号：US13833555
申请日：2013-03-15
Applicant: Janssen Biotech, Inc.
Inventor： Mack Flinspach , Michael Hunter , Yi Liu , Robert Neff , Alan Wickenden , Alan Gibbs
IPC: C07K14/435
CPC classification number: C07K14/43518 , A61K38/00
Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.
Abstract translation: 本发明涉及Huwentoxin-IV变体，编码它们的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：US10414808B2
公开(公告)日：2019-09-17
申请号：US14399088
申请日：2013-03-15
Applicant: JANSSEN BIOTECH, INC.
Inventor： William Eckert , Mack Flinspach , Michael Hunter , Yi Liu , Robert Neff , Alan Wickenden , Alan Gibbs
IPC: A61K38/00 , C07K14/435
Abstract: The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, methods of making and using the foregoing, and methods of alleviating pain with peptide inhibitors of Nav1.7.
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